DK407384A - Corticoidderivater - Google Patents
Corticoidderivater Download PDFInfo
- Publication number
- DK407384A DK407384A DK407384A DK407384A DK407384A DK 407384 A DK407384 A DK 407384A DK 407384 A DK407384 A DK 407384A DK 407384 A DK407384 A DK 407384A DK 407384 A DK407384 A DK 407384A
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- eczema
- disorder
- corticoid
- corticoid derivatives
- Prior art date
Links
- RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical class C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 title abstract 2
- 201000004624 Dermatitis Diseases 0.000 abstract 2
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 206010012442 Dermatitis contact Diseases 0.000 abstract 1
- 208000032041 Hearing impaired Diseases 0.000 abstract 1
- 208000022873 Ocular disease Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 208000010247 contact dermatitis Diseases 0.000 abstract 1
- 208000014617 hemorrhoid Diseases 0.000 abstract 1
- 208000003265 stomatitis Diseases 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 208000001319 vasomotor rhinitis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58164772A JPS6056997A (ja) | 1983-09-07 | 1983-09-07 | 新規な６−酸素化コルチコイド／７α−カ−ボネ−ト誘導体およびその製法 |
| JP16477283 | 1983-09-07 | ||
| JP12043984 | 1984-06-12 | ||
| JP59120439A JPS611698A (ja) | 1984-06-12 | 1984-06-12 | 新規なコルチコイド誘導体およびその製法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK407384D0 DK407384D0 (da) | 1984-08-24 |
| DK407384A true DK407384A (da) | 1985-03-08 |
| DK168631B1 DK168631B1 (da) | 1994-05-09 |
Family
ID=26458022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK407384A DK168631B1 (da) | 1983-09-07 | 1984-08-24 | Corticoidderivater, fremgangsmåde til fremstilling af corticoidderivaterne, farmaceutisk præparat indeholdende corticoidderivaterne samt mellemprodukter |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0136586B1 (da) |
| AT (1) | ATE41013T1 (da) |
| AU (1) | AU558725B2 (da) |
| DD (3) | DD232497A5 (da) |
| DE (1) | DE3476885D1 (da) |
| DK (1) | DK168631B1 (da) |
| HU (2) | HUT44040A (da) |
| NO (1) | NO843548L (da) |
| SU (2) | SU1561827A3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4025342A1 (de) * | 1990-08-10 | 1992-02-13 | Hoechst Ag | In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| PT900234E (pt) | 1996-05-01 | 2000-12-29 | Us Gov Health & Human Serv | Derivados de progesterona substituidos em 21 que podem ser utilizados como novos agentes antiprogestativos |
| US6900193B1 (en) | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1518179B1 (de) * | 1964-10-07 | 1970-01-02 | Warner Lambert Pharmaceutical | Verfahren zur Herstellung von 17alpha-Acyloxy-20-keto-21-desoxy-steroiden |
| US3558675A (en) * | 1969-06-30 | 1971-01-26 | Merck & Co Inc | Steroid carbonates and process |
| GB1440063A (en) * | 1972-08-11 | 1976-06-23 | Glaxo Lab Ltd | 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids |
| DE2735110A1 (de) * | 1977-08-04 | 1979-02-15 | Hoechst Ag | Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung |
| DE2817988A1 (de) * | 1978-04-25 | 1979-11-08 | Hoechst Ag | Corticoid 17-alkylcarbonate und verfahren zu deren herstellung |
| DE3133082A1 (de) * | 1981-08-18 | 1983-03-10 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue hydrocortison-derivate, ihre herstellung und verwendung |
-
1984
- 1984-08-23 AU AU32311/84A patent/AU558725B2/en not_active Ceased
- 1984-08-24 DK DK407384A patent/DK168631B1/da not_active IP Right Cessation
- 1984-09-04 HU HU852282A patent/HUT44040A/hu unknown
- 1984-09-04 HU HU843321A patent/HU201092B/hu not_active IP Right Cessation
- 1984-09-05 AT AT84110572T patent/ATE41013T1/de not_active IP Right Cessation
- 1984-09-05 DE DE8484110572T patent/DE3476885D1/de not_active Expired
- 1984-09-05 EP EP84110572A patent/EP0136586B1/en not_active Expired
- 1984-09-06 DD DD84267066A patent/DD232497A5/de not_active IP Right Cessation
- 1984-09-06 NO NO843548A patent/NO843548L/no unknown
- 1984-09-06 DD DD84274493A patent/DD229135A5/de not_active IP Right Cessation
- 1984-09-06 DD DD84275355A patent/DD229702A5/de not_active IP Right Cessation
- 1984-09-06 SU SU843792254A patent/SU1561827A3/ru active
-
1987
- 1987-11-17 SU SU874203674A patent/SU1551250A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE41013T1 (de) | 1989-03-15 |
| SU1561827A3 (ru) | 1990-04-30 |
| AU3231184A (en) | 1985-03-14 |
| HUT37944A (en) | 1986-03-28 |
| SU1551250A3 (ru) | 1990-03-15 |
| DK168631B1 (da) | 1994-05-09 |
| HU201092B (en) | 1990-09-28 |
| DD229702A5 (de) | 1985-11-13 |
| AU558725B2 (en) | 1987-02-05 |
| DD232497A5 (de) | 1986-01-29 |
| NO843548L (no) | 1985-03-08 |
| DK407384D0 (da) | 1984-08-24 |
| EP0136586B1 (en) | 1989-03-01 |
| EP0136586A2 (en) | 1985-04-10 |
| EP0136586A3 (en) | 1986-01-29 |
| HUT44040A (en) | 1988-01-28 |
| DD229135A5 (de) | 1985-10-30 |
| DE3476885D1 (en) | 1989-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |