DK421488D0 - Pyridiniumderivater og deres anvendelse - Google Patents

Pyridiniumderivater og deres anvendelse

Info

Publication number: DK421488D0
Authority: DK; Denmark
Prior art keywords: pyridinium derivatives; pyridinium; derivatives
Prior art date: 1987-07-31

Application number

DK421488A

Other languages

English (en)

Other versions

DK421488A (da

Inventor

Susumu Tsushima

Muneo Takatani

Kohei Nishikawa

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-31

Filing date

1988-07-28

Publication date

1988-07-28

1988-07-28 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1988-07-28 Publication of DK421488D0 publication Critical patent/DK421488D0/da

1989-02-01 Publication of DK421488A publication Critical patent/DK421488A/da

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/18—Salts thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Quinoline Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK421488A 1987-07-31 1988-07-28 Pyridiniumderivater og deres anvendelse DK421488A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP19347987		1987-07-31
JP13890888		1988-06-06

Publications (2)

Publication Number	Publication Date
DK421488D0 true DK421488D0 (da)	1988-07-28
DK421488A DK421488A (da)	1989-02-01

Family

ID=26471848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK421488A DK421488A (da)	1987-07-31	1988-07-28	Pyridiniumderivater og deres anvendelse

Country Status (11)

Country	Link
US (1)	US4962113A (da)
EP (1)	EP0301751B1 (da)
JP (1)	JP2756975B2 (da)
KR (1)	KR0125929B1 (da)
AU (1)	AU613653B2 (da)
CA (1)	CA1339645C (da)
DE (1)	DE3879024T2 (da)
DK (1)	DK421488A (da)
HU (1)	HU211704A9 (da)
IE (1)	IE69971B1 (da)
IL (1)	IL87189A (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2824536B2 (ja)	1989-01-30	1998-11-11	武田薬品工業株式会社	ピリジニウム誘導体
US4981860A (en) *	1989-01-30	1991-01-01	Takeda Chemical Industries, Ltd.	Pyridinium nitrate, composition containing same and their use for inhibiting platelet activating factor
FR2676053B1 (fr) *	1991-05-03	1993-08-27	Sanofi Elf	Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5208247A (en) *	1991-08-01	1993-05-04	American Cyanamid Company	Pyridinium compounds which are useful as antagonists of platelet activating factor
US5314902A (en) *	1993-01-27	1994-05-24	Monsanto Company	Urea derivatives useful as platelet aggregation inhibitors
ES2068742B1 (es) *	1993-02-11	1995-11-16	Uriach & Cia Sa J	Nuevos derivados de piridinio.
ES2062943B1 (es) *	1993-03-23	1995-11-16	Uriach & Cia Sa J	Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.
EP0709375B1 (en) *	1994-10-25	2005-05-18	AstraZeneca AB	Therapeutic heterocycles
US5998444A (en) *	1995-10-24	1999-12-07	Zeneca Ltd.	Piperidinyl compounds as NK1 or NK2 antagonists
TW370459B (en) *	1996-06-03	1999-09-21	Shiseido Co Ltd	Hair revitalizing tonic composition containing a lipid derivative and use thereof
WO1998004547A1 (en) *	1996-07-25	1998-02-05	Takeda Chemical Industries, Ltd.	Crystalline pyridinium derivatives as paf-antagonists
US6177067B1 (en)	1996-08-09	2001-01-23	Shiseido Company, Ltd.	Hair revitalizing tonic composition containing a 2,2-dimethylpropanediol compound and use thereof
US20110140056A1 (en) *	2003-07-01	2011-06-16	Transitions Optical, Inc.	Indeno-fused ring compounds
US8518546B2 (en) *	2003-07-01	2013-08-27	Transitions Optical, Inc.	Photochromic compounds and compositions
US8545984B2 (en) *	2003-07-01	2013-10-01	Transitions Optical, Inc.	Photochromic compounds and compositions
DE202009000591U1 (de)	2009-01-19	2010-06-17	Ets Energie Transfersysteme Ag	Aqua-Ofenbox
TW201534586A (zh)	2013-06-11	2015-09-16	Orion Corp	新穎ｃｙｐ１７抑制劑／抗雄激素劑
MX2020003242A (es)	2017-09-22	2020-09-18	Jubilant Epipad LLC	Compuestos heterociclicos como inhibidores de pad.
AU2018352142B2 (en)	2017-10-18	2022-08-25	Jubilant Epipad LLC	Imidazo-pyridine compounds as PAD inhibitors
KR20200085836A (ko)	2017-11-06	2020-07-15	주빌런트 프로델 엘엘씨	Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
BR112020010322A2 (pt)	2017-11-24	2020-11-17	Jubilant Episcribe Llc	composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer
SG11202008950PA (en)	2018-03-13	2020-10-29	Jubilant Prodel LLC	Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2270878B1 (da) *	1974-05-15	1978-02-03	Fabre Sa Pierre
US4657917A (en)	1982-02-08	1987-04-14	Research Corporation	Platelet aggregation inhibitory agents
DK160818C (da) *	1983-12-30	1991-10-07	Hoffmann La Roche	N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse
EP0157609B1 (en) *	1984-04-03	1992-10-14	Takeda Chemical Industries, Ltd.	Lipid derivatives their production and use
AU4635885A (en) *	1984-07-19	1986-02-25	University Of Florida	Compounds for site-enhanced delivery of radionuclides and uses thereof
US4698093A (en) *	1984-11-06	1987-10-06	Monsanto Company	Herbicidal (2 or 6)-fluoroalkyl-4-amino pyridine derivatives
DK161702C (da) *	1985-04-04	1992-01-13	Hoffmann La Roche	N-(2-phenoxyethyl)nicotinamid-derivater, deres fremstilling, fungicide midler indeholdende derivaterne, samt anvendelse af derivaterne og midlerne
JP2556849B2 (ja) *	1986-02-13	1996-11-27	三共株式会社	グリセリン誘導体

1988
- 1988-07-20 DE DE88306622T patent/DE3879024T2/de not_active Expired - Fee Related
- 1988-07-20 EP EP88306622A patent/EP0301751B1/en not_active Expired - Lifetime
- 1988-07-22 IL IL8718988A patent/IL87189A/en not_active IP Right Cessation
- 1988-07-25 JP JP63186494A patent/JP2756975B2/ja not_active Expired - Fee Related
- 1988-07-26 US US07/224,352 patent/US4962113A/en not_active Expired - Fee Related
- 1988-07-27 AU AU20101/88A patent/AU613653B2/en not_active Ceased
- 1988-07-28 DK DK421488A patent/DK421488A/da not_active Application Discontinuation
- 1988-07-29 IE IE233588A patent/IE69971B1/en not_active IP Right Cessation
- 1988-07-29 CA CA000573439A patent/CA1339645C/en not_active Expired - Fee Related
- 1988-07-30 KR KR1019880009705A patent/KR0125929B1/ko not_active Expired - Fee Related
1995
- 1995-06-30 HU HU95P/P00610P patent/HU211704A9/hu unknown

Also Published As

Publication number	Publication date
DK421488A (da)	1989-02-01
IL87189A0 (en)	1988-12-30
IE69971B1 (en)	1996-10-16
EP0301751A1 (en)	1989-02-01
KR890002009A (ko)	1989-04-07
JPH0276854A (ja)	1990-03-16
DE3879024T2 (de)	1993-10-07
HU211704A9 (en)	1995-12-28
US4962113A (en)	1990-10-09
AU613653B2 (en)	1991-08-08
AU2010188A (en)	1989-02-09
IE882335L (en)	1989-01-31
JP2756975B2 (ja)	1998-05-25
EP0301751B1 (en)	1993-03-10
IL87189A (en)	1996-07-23
DE3879024D1 (de)	1993-04-15
KR0125929B1 (ko)	1997-12-26
CA1339645C (en)	1998-01-27

Legal Events

Date	Code	Title	Description
2001-02-26	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK421488A (da)	1989-02-01	Pyridiniumderivater og deres anvendelse
DK543189A (da)	1990-05-02	Lysyloxidaseinhibitorer og deres anvendelse
DK41484D0 (da)	1984-01-30	Beta-phenethanolaminer og deres anvendelse
DK317588A (da)	1988-12-12	2-anilino-pyrimidin-derivat samt deres fremstilling og anvendelse
DK714688D0 (da)	1988-12-21	Flokkuleringsstabile pigmenter og deres anvendelse
DK349088D0 (da)	1988-06-24	Haerdelige blandinger og deres anvendelse
DK595388A (da)	1989-04-28	Benzopyranderivater, deres fremstilling og anvendelse
DK45188D0 (da)	1988-01-29	Substituerede aminderivater og deres anvendelse
DK193088D0 (da)	1988-04-08	2-acylpyrrolidin-derivater, deres fremstilling og anvendelse
DK293888A (da)	1988-12-10	Fenolderivater og deres fremstilling og anvendelse
DK614084D0 (da)	1984-12-20	Milbemycim-derivater samt deres fremstilling og anvendelse
DK294684D0 (da)	1984-06-15	N-alkylerede 3-phenyl-4-cyanopyrrol-derivater samt deres fremstilling og anvendelse
DK278188D0 (da)	1988-05-20	Thiazolidin-4-on-derivater, deres fremstilling og anvendelse
DK558484A (da)	1985-05-26	Milbemycinderivater samt deres fremstilling og anvendelse
DK189488D0 (da)	1988-04-07	Imidazothiadiazinderivater, deres fremstilling og anvendelse
DK634089A (da)	1990-06-16	Polyhydroxybenzyloxypropanolaminer og deres anvendelse
DK223288A (da)	1988-10-25	Benzensulfornamid-derivater, deres fremstilling og anvendelse
DK412188A (da)	1989-01-24	Benzothiazinon-derivater, deres fremstilling og anvendelse
DK361388A (da)	1989-01-02	Cephemderivater, deres fremstilling og anvendelse
DK613888D0 (da)	1988-11-03	Acyllabdan-derivater, deres fremstilling og anvendelse
DK668888D0 (da)	1988-11-30	Labdan-derivater, deres fremstilling og anvendelse
DK668788D0 (da)	1988-11-30	Labdanderivater, deres fremstilling og anvendelse
DK619589A (da)	1990-06-10	Sphingenin og derivater heraf
DK133687D0 (da)	1987-03-16	Pyridinderivater samt deres fremstilling og anvendelse
DK727388D0 (da)	1988-12-29	2-aminotetrahydroisoquinolinderivater, deres fremstilling og anvendelse