DK4228676T3 - Sammensætninger egnet til anvendelse hos nyfødte - Google Patents

Sammensætninger egnet til anvendelse hos nyfødte Download PDF

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Publication number
DK4228676T3
DK4228676T3 DK21807381.5T DK21807381T DK4228676T3 DK 4228676 T3 DK4228676 T3 DK 4228676T3 DK 21807381 T DK21807381 T DK 21807381T DK 4228676 T3 DK4228676 T3 DK 4228676T3
Authority
DK
Denmark
Prior art keywords
newborns
compositions suitable
compositions
Prior art date
Application number
DK21807381.5T
Other languages
English (en)
Inventor
Nazila Salamat-Miller
Katherine Taylor
Bing He
Indranil Bhattacharya
Linda Han
Benita Amsden
James Kranz
Original Assignee
Oak Hill Bio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oak Hill Bio Ltd filed Critical Oak Hill Bio Ltd
Application granted granted Critical
Publication of DK4228676T3 publication Critical patent/DK4228676T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754Insulin-like growth factor binding proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK21807381.5T 2020-10-19 2021-10-19 Sammensætninger egnet til anvendelse hos nyfødte DK4228676T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063093696P 2020-10-19 2020-10-19
PCT/US2021/055598 WO2022086953A1 (en) 2020-10-19 2021-10-19 Compositions suitable for use in neonates

Publications (1)

Publication Number Publication Date
DK4228676T3 true DK4228676T3 (da) 2025-01-20

Family

ID=78622033

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21807381.5T DK4228676T3 (da) 2020-10-19 2021-10-19 Sammensætninger egnet til anvendelse hos nyfødte

Country Status (24)

Country Link
US (1) US20230381285A1 (da)
EP (2) EP4228676B1 (da)
JP (1) JP7827315B2 (da)
KR (1) KR20230113287A (da)
CN (1) CN117098547A (da)
AU (1) AU2021364523A1 (da)
CA (1) CA3194764A1 (da)
DK (1) DK4228676T3 (da)
ES (1) ES3005966T3 (da)
FI (1) FI4228676T3 (da)
HR (1) HRP20250193T1 (da)
HU (1) HUE070409T2 (da)
IL (1) IL301688A (da)
LT (1) LT4228676T (da)
MX (1) MX2023004426A (da)
PL (1) PL4228676T3 (da)
PT (1) PT4228676T (da)
RS (1) RS66493B1 (da)
SA (1) SA523440271B1 (da)
SI (1) SI4228676T1 (da)
SM (1) SMT202500093T1 (da)
TW (1) TWI912393B (da)
WO (1) WO2022086953A1 (da)
ZA (1) ZA202303162B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023210427A1 (en) 2022-01-19 2024-08-22 Oak Hill Bio Limited Compositions and methods for reducing oxidation of igf‐1/igfbp
WO2023213908A1 (en) 2022-05-04 2023-11-09 Oak Hill Bio Limited Combination therapy for preterm infants
WO2023242439A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
JP2025533683A (ja) * 2022-10-04 2025-10-08 オーク ヒル バイオ リミテッド Igf-1複合体で新生児を処置する方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
ATE90690T1 (de) 1987-04-06 1993-07-15 Celtrix Pharma Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
ATE132164T1 (de) 1988-04-12 1996-01-15 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
GB8826451D0 (en) 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
WO1993023067A1 (en) 1992-05-08 1993-11-25 Thomas Jefferson University Igf-1 analogs
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
WO1998011913A1 (en) * 1996-09-16 1998-03-26 Dalhousie University Use of igf-i for the treatment of polycystic kidney disease and related indications
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6436897B2 (en) * 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US20020028764A1 (en) * 2000-09-04 2002-03-07 Aarhus Amt. Treatment of acute and chronic liver disease
BRPI0611901A2 (pt) * 2005-06-14 2012-08-28 Amgen, Inc composição, liofilizado, kit, e, processo para preparar uma composição
EP2501367B1 (en) * 2009-11-17 2015-01-21 Ipsen Pharma S.A.S. Formulation for HGH and RHIGF-1 combination
MX2015008944A (es) * 2013-01-15 2016-06-21 Teva Pharma Proceso de liofilizacion.
KR20140119396A (ko) * 2013-03-29 2014-10-10 삼성전자주식회사 단백질 약물의 액상 제형
CA3075482A1 (en) * 2017-09-11 2019-03-14 Shire Human Genetic Therapies, Inc. Methods and compositions for treating chronic lung diseases
AU2023210427A1 (en) * 2022-01-19 2024-08-22 Oak Hill Bio Limited Compositions and methods for reducing oxidation of igf‐1/igfbp
EP4469806A1 (en) * 2022-01-24 2024-12-04 Oak Hill Bio Limited Lot release assays for igf?1/igfbp complexes

Also Published As

Publication number Publication date
FI4228676T3 (fi) 2025-02-26
WO2022086953A9 (en) 2022-07-07
HRP20250193T1 (hr) 2025-04-11
PL4228676T3 (pl) 2025-04-07
IL301688A (en) 2023-05-01
ZA202303162B (en) 2024-08-28
EP4228676B1 (en) 2025-01-08
JP7827315B2 (ja) 2026-03-10
SI4228676T1 (sl) 2025-03-31
TWI912393B (zh) 2026-01-21
WO2022086953A1 (en) 2022-04-28
RS66493B1 (sr) 2025-03-31
CN117098547A (zh) 2023-11-21
ES3005966T3 (en) 2025-03-17
KR20230113287A (ko) 2023-07-28
US20230381285A1 (en) 2023-11-30
EP4228676A1 (en) 2023-08-23
CA3194764A1 (en) 2022-04-28
SA523440271B1 (ar) 2025-04-10
SMT202500093T1 (it) 2025-03-12
PT4228676T (pt) 2025-01-24
EP4534073A2 (en) 2025-04-09
EP4534073A3 (en) 2025-05-14
TW202233228A (zh) 2022-09-01
LT4228676T (lt) 2025-02-10
AU2021364523A1 (en) 2023-04-06
MX2023004426A (es) 2023-08-04
JP2023550203A (ja) 2023-11-30
HUE070409T2 (hu) 2025-06-28

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