DK423184A - 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin d og farmaceutisk acceptable salte deraf samt forbindelser til anvendelse som mellemprodukter ved fremstilling deraf - Google Patents

9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin d og farmaceutisk acceptable salte deraf samt forbindelser til anvendelse som mellemprodukter ved fremstilling deraf Download PDF

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Publication number
DK423184A
DK423184A DK423184A DK423184A DK423184A DK 423184 A DK423184 A DK 423184A DK 423184 A DK423184 A DK 423184A DK 423184 A DK423184 A DK 423184A DK 423184 A DK423184 A DK 423184A
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Prior art keywords
homoerythromycin
deoxo
aza
intermediates
relationships
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DK423184A
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English (en)
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DK423184D0 (da
DK157877C (da
DK157877B (da
Inventor
Gene Michael Bright
James Robert Hauske
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Pfizer
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Publication of DK423184D0 publication Critical patent/DK423184D0/da
Publication of DK423184A publication Critical patent/DK423184A/da
Publication of DK157877B publication Critical patent/DK157877B/da
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Publication of DK157877C publication Critical patent/DK157877C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK423184A 1983-09-06 1984-09-05 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin d og farmaceutisk acceptable syreadditionssalte deraf samt 9-deoxo-9a-aza-9a-homoerythromycin d til anvendelse som udgangsmateriale ved fremstilling deraf DK157877C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52982883 1983-09-06
US06/529,828 US4465674A (en) 1983-09-06 1983-09-06 Azahomoerythromycin D derivative and intermediates therefor

Publications (4)

Publication Number Publication Date
DK423184D0 DK423184D0 (da) 1984-09-05
DK423184A true DK423184A (da) 1985-03-07
DK157877B DK157877B (da) 1990-02-26
DK157877C DK157877C (da) 1990-07-23

Family

ID=24111406

Family Applications (1)

Application Number Title Priority Date Filing Date
DK423184A DK157877C (da) 1983-09-06 1984-09-05 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin d og farmaceutisk acceptable syreadditionssalte deraf samt 9-deoxo-9a-aza-9a-homoerythromycin d til anvendelse som udgangsmateriale ved fremstilling deraf

Country Status (7)

Country Link
US (1) US4465674A (da)
EP (1) EP0136830A3 (da)
JP (1) JPS6072897A (da)
CA (1) CA1240320A (da)
DK (1) DK157877C (da)
ES (1) ES8604256A1 (da)
GR (1) GR80278B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
WO1989004167A1 (en) * 1987-11-10 1989-05-18 Pfizer Inc. Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza-9a-homoerythromycin a derivatives
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
AU2001280000A1 (en) * 2000-08-23 2002-03-04 Jaweed Mukarram, Siddiqui Mohammed Process for preparation of anhydrous azithromycin
US20040067898A1 (en) * 2001-11-27 2004-04-08 John Somberg Synthesis and separation of optically active isomers of erythromycin and their biological actions
DE60209704T2 (de) * 2001-05-22 2006-11-16 Pfizer Products Inc., Groton Neue kristallforme von azithromycin
US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
JP4762648B2 (ja) * 2005-08-30 2011-08-31 三和シヤッター工業株式会社 窓装置のロック装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3736313A (en) * 1971-02-26 1973-05-29 Abbott Lab Erythromycin derivatives
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4496546A (en) * 1982-04-12 1985-01-29 Pfizer Inc. Erythromycin D and esters thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof

Also Published As

Publication number Publication date
ES535625A0 (es) 1986-01-16
JPS6072897A (ja) 1985-04-24
EP0136830A2 (en) 1985-04-10
GR80278B (en) 1985-01-04
DK423184D0 (da) 1984-09-05
ES8604256A1 (es) 1986-01-16
DK157877C (da) 1990-07-23
US4465674A (en) 1984-08-14
CA1240320A (en) 1988-08-09
DK157877B (da) 1990-02-26
EP0136830A3 (en) 1986-03-19

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