DK4236932T3 - Degraderende forbindelse i et lægemiddel - Google Patents

Degraderende forbindelse i et lægemiddel

Info

Publication number
DK4236932T3
DK4236932T3 DK21887770.2T DK21887770T DK4236932T3 DK 4236932 T3 DK4236932 T3 DK 4236932T3 DK 21887770 T DK21887770 T DK 21887770T DK 4236932 T3 DK4236932 T3 DK 4236932T3
Authority
DK
Denmark
Prior art keywords
medicine
degrading compound
degrading
compound
Prior art date
Application number
DK21887770.2T
Other languages
English (en)
Inventor
Rhett Mead Schiffman
Bruce Alan Firestone
Original Assignee
Visus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visus Therapeutics Inc filed Critical Visus Therapeutics Inc
Application granted granted Critical
Publication of DK4236932T3 publication Critical patent/DK4236932T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DK21887770.2T 2020-11-02 2021-11-02 Degraderende forbindelse i et lægemiddel DK4236932T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063108720P 2020-11-02 2020-11-02
US202163162367P 2021-03-17 2021-03-17
US202163257024P 2021-10-18 2021-10-18
PCT/US2021/057720 WO2022094462A1 (en) 2020-11-02 2021-11-02 Degradant compound in a medicament

Publications (1)

Publication Number Publication Date
DK4236932T3 true DK4236932T3 (da) 2026-02-09

Family

ID=81383327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21887770.2T DK4236932T3 (da) 2020-11-02 2021-11-02 Degraderende forbindelse i et lægemiddel

Country Status (20)

Country Link
US (2) US20230390284A1 (da)
EP (1) EP4236932B1 (da)
JP (1) JP2023548336A (da)
KR (1) KR20230104645A (da)
AU (1) AU2021369566A1 (da)
CA (1) CA3195784A1 (da)
CL (1) CL2023001258A1 (da)
CO (1) CO2023007133A2 (da)
CR (1) CR20230190A (da)
DK (1) DK4236932T3 (da)
ES (1) ES3061413T3 (da)
FI (1) FI4236932T3 (da)
HR (1) HRP20260130T1 (da)
LT (1) LT4236932T (da)
MA (1) MA62049B1 (da)
MX (1) MX2023005031A (da)
PT (1) PT4236932T (da)
RS (1) RS67818B1 (da)
TW (1) TW202233170A (da)
WO (1) WO2022094462A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117571883B (zh) * 2024-01-15 2024-03-19 四川智强医药科技开发有限公司 一种酒石酸溴莫尼定滴眼液的质量检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10980818B2 (en) * 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US8299079B2 (en) * 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
BR112012018154A2 (pt) * 2010-01-21 2016-04-05 Allergan Inc agonista alfa-2 adrenérgico tendo longa duração do efeito de redução da pressão intraocular
KR102667598B1 (ko) * 2015-06-18 2024-05-20 렌즈 테라퓨틱스 인코포레이티드 눈의 굴절 이상 치료 및 원거리 시력 개선용 조성물 및 방법
CN108883102A (zh) * 2016-03-17 2018-11-23 远视眼治疗有限责任公司 用于治疗远视眼的组合物和方法
AU2018371787A1 (en) * 2017-11-21 2020-11-05 Sydnexis, Inc. Ophthalmic composition and delivery device thereof
EP3980005A4 (en) 2019-06-10 2023-09-20 Visus Therapeutics, Inc. CARABACHOL BROMONIDINE FORMULATION TO IMPROVE ANTI-PREBSYOPIA EFFECT

Also Published As

Publication number Publication date
WO2022094462A1 (en) 2022-05-05
EP4236932A4 (en) 2024-10-09
FI4236932T3 (fi) 2026-02-12
ES3061413T3 (en) 2026-04-01
CL2023001258A1 (es) 2023-12-22
EP4236932B1 (en) 2026-01-07
CA3195784A1 (en) 2022-05-05
CO2023007133A2 (es) 2023-06-20
HRP20260130T1 (hr) 2026-03-27
EP4236932A1 (en) 2023-09-06
US20230390284A1 (en) 2023-12-07
JP2023548336A (ja) 2023-11-16
MA62049B1 (fr) 2026-02-27
TW202233170A (zh) 2022-09-01
KR20230104645A (ko) 2023-07-10
PT4236932T (pt) 2026-02-23
AU2021369566A9 (en) 2025-04-10
MX2023005031A (es) 2023-06-29
US20240100046A1 (en) 2024-03-28
LT4236932T (lt) 2026-03-25
AU2021369566A1 (en) 2023-06-22
CR20230190A (es) 2023-09-06
RS67818B1 (sr) 2026-03-31

Similar Documents

Publication Publication Date Title
IL288466A (en) Devices and methods for precision dose delivery
JP1704655S (ja) 医療用注入器
JP1705350S (ja) 医療用注入器
EP4221690A4 (en) PHARMACEUTICAL COMPOSITIONS
EP4135699A4 (en) Pharmaceutical compositions
EP4003293C0 (en) PHARMACEUTICAL DEVELOPMENT
PL4208227T3 (pl) Urządzenia do podawania leku z głowicą do wielokrotnego dawkowania
DK4236932T3 (da) Degraderende forbindelse i et lægemiddel
EP4434969A4 (en) ANTI-SARS-CoV-2 MEDICATION
JP1738571S (ja) 薬用パッケージ
EP4157297A4 (en) Airway medicaments
EP4087442C0 (de) Interdental-reiniger
EP4431151A4 (en) ANTI-SARS-COV-2 MEDICINES
EP4413332A4 (en) INTEGRATED DOSE COUNTER
EP4331642A4 (en) INJECTION
EP4349366A4 (en) PHARMACEUTICAL COMPOSITION
EP4268830A4 (en) PHARMACEUTICAL COMPOSITION
EP4265253A4 (en) PHARMACEUTICAL COMPOSITION
EP4265252A4 (en) Pharmaceutical composition
EP4144391A4 (en) INJECTION
EP4489751A4 (en) MEDICINE
PL4558202T3 (pl) Licznik dawek
KR102687712B9 (ko) 의약품 주입기
IT202300013965A1 (it) Siringa a doppia iniezione
CL2022002441S1 (es) Jeringa