RS67818B1 - Degradantno jedinjenje u leku - Google Patents

Degradantno jedinjenje u leku

Info

Publication number
RS67818B1
RS67818B1 RS20260189A RSP20260189A RS67818B1 RS 67818 B1 RS67818 B1 RS 67818B1 RS 20260189 A RS20260189 A RS 20260189A RS P20260189 A RSP20260189 A RS P20260189A RS 67818 B1 RS67818 B1 RS 67818B1
Authority
RS
Serbia
Prior art keywords
medicament
degradant
compound
degradant compound
Prior art date
Application number
RS20260189A
Other languages
English (en)
Inventor
Rhett Mead Schiffman
Bruce Alan Firestone
Original Assignee
Visus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visus Therapeutics Inc filed Critical Visus Therapeutics Inc
Publication of RS67818B1 publication Critical patent/RS67818B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
RS20260189A 2020-11-02 2021-11-02 Degradantno jedinjenje u leku RS67818B1 (sr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063108720P 2020-11-02 2020-11-02
US202163162367P 2021-03-17 2021-03-17
US202163257024P 2021-10-18 2021-10-18
EP21887770.2A EP4236932B1 (en) 2020-11-02 2021-11-02 Degradant compound in a medicament
PCT/US2021/057720 WO2022094462A1 (en) 2020-11-02 2021-11-02 Degradant compound in a medicament

Publications (1)

Publication Number Publication Date
RS67818B1 true RS67818B1 (sr) 2026-03-31

Family

ID=81383327

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20260189A RS67818B1 (sr) 2020-11-02 2021-11-02 Degradantno jedinjenje u leku

Country Status (21)

Country Link
US (2) US20230390284A1 (sr)
EP (2) EP4236932B1 (sr)
JP (1) JP2023548336A (sr)
KR (1) KR20230104645A (sr)
AU (1) AU2021369566A1 (sr)
CA (1) CA3195784A1 (sr)
CL (1) CL2023001258A1 (sr)
CO (1) CO2023007133A2 (sr)
CR (1) CR20230190A (sr)
DK (1) DK4236932T3 (sr)
ES (1) ES3061413T3 (sr)
FI (1) FI4236932T3 (sr)
HR (1) HRP20260130T1 (sr)
LT (1) LT4236932T (sr)
MA (1) MA62049B1 (sr)
MX (1) MX2023005031A (sr)
PT (1) PT4236932T (sr)
RS (1) RS67818B1 (sr)
SI (1) SI4236932T1 (sr)
TW (1) TW202233170A (sr)
WO (1) WO2022094462A1 (sr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117571883B (zh) * 2024-01-15 2024-03-19 四川智强医药科技开发有限公司 一种酒石酸溴莫尼定滴眼液的质量检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10980818B2 (en) * 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US8299079B2 (en) * 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
US9889088B2 (en) * 2010-01-21 2018-02-13 Allergan, Inc. Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
KR20180014825A (ko) * 2015-06-18 2018-02-09 프레스바이오피아 세라피스, 엘엘씨 눈의 굴절 이상 치료 및 원거리 시력 개선용 조성물 및 방법
CN108883102A (zh) * 2016-03-17 2018-11-23 远视眼治疗有限责任公司 用于治疗远视眼的组合物和方法
US20200345542A1 (en) * 2017-11-21 2020-11-05 Sydnexis, Inc. Ophthalmic composition and delivery device thereof
CN114502155A (zh) * 2019-06-10 2022-05-13 视觉治疗股份有限公司 增强抗老视作用的卡巴胆碱-溴莫尼定制剂

Also Published As

Publication number Publication date
EP4236932B1 (en) 2026-01-07
CO2023007133A2 (es) 2023-06-20
DK4236932T3 (da) 2026-02-09
TW202233170A (zh) 2022-09-01
CR20230190A (es) 2023-09-06
FI4236932T3 (fi) 2026-02-12
MX2023005031A (es) 2023-06-29
MA62049B1 (fr) 2026-02-27
AU2021369566A1 (en) 2023-06-22
EP4236932A4 (en) 2024-10-09
SI4236932T1 (sl) 2026-04-30
LT4236932T (lt) 2026-03-25
CL2023001258A1 (es) 2023-12-22
JP2023548336A (ja) 2023-11-16
WO2022094462A1 (en) 2022-05-05
EP4236932A1 (en) 2023-09-06
PT4236932T (pt) 2026-02-23
US20240100046A1 (en) 2024-03-28
US20230390284A1 (en) 2023-12-07
AU2021369566A9 (en) 2025-04-10
KR20230104645A (ko) 2023-07-10
ES3061413T3 (en) 2026-04-01
HRP20260130T1 (hr) 2026-03-27
EP4736853A2 (en) 2026-05-06
CA3195784A1 (en) 2022-05-05

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