DK4267144T3 - Topisk braf inhibitorsammensætninger til behandling af egfrnedstrøms effektor-inducerede reaktioner - Google Patents

Topisk braf inhibitorsammensætninger til behandling af egfrnedstrøms effektor-inducerede reaktioner

Info

Publication number
DK4267144T3
DK4267144T3 DK21909623.7T DK21909623T DK4267144T3 DK 4267144 T3 DK4267144 T3 DK 4267144T3 DK 21909623 T DK21909623 T DK 21909623T DK 4267144 T3 DK4267144 T3 DK 4267144T3
Authority
DK
Denmark
Prior art keywords
braf inhibitor
downstream effector
inhibitor compositions
induced reactions
treating egfr
Prior art date
Application number
DK21909623.7T
Other languages
English (en)
Inventor
Noa Shelach
Galit Zelinger
Original Assignee
Lutris Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lutris Pharma Ltd filed Critical Lutris Pharma Ltd
Application granted granted Critical
Publication of DK4267144T3 publication Critical patent/DK4267144T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
DK21909623.7T 2020-12-24 2021-11-19 Topisk braf inhibitorsammensætninger til behandling af egfrnedstrøms effektor-inducerede reaktioner DK4267144T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063130483P 2020-12-24 2020-12-24
PCT/IB2021/000799 WO2022136912A1 (en) 2020-12-24 2021-11-19 Topical braf inhibitor compositions for treatment of egfr downstream effectors - induced reactions

Publications (1)

Publication Number Publication Date
DK4267144T3 true DK4267144T3 (da) 2026-03-30

Family

ID=82157434

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21909623.7T DK4267144T3 (da) 2020-12-24 2021-11-19 Topisk braf inhibitorsammensætninger til behandling af egfrnedstrøms effektor-inducerede reaktioner

Country Status (9)

Country Link
US (1) US20230321106A1 (da)
EP (1) EP4267144B1 (da)
CN (1) CN116669739A (da)
CA (1) CA3203021A1 (da)
DK (1) DK4267144T3 (da)
ES (1) ES3060285T3 (da)
IL (1) IL303804A (da)
MX (1) MX2023007547A (da)
WO (1) WO2022136912A1 (da)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5833007B2 (ja) * 2009-08-31 2015-12-16 ドクター・レディーズ・ラボラトリーズ・リミテッド ステロイドを含む局所製剤
ES2947237T3 (es) * 2016-03-10 2023-08-03 Lutris Pharma Ltd Uso de inhibidores de BRaf para el tratamiento de reacciones cutáneas
WO2017223245A1 (en) * 2016-06-21 2017-12-28 The Regents Of The University Of California Wound healing using braf inhibitors
WO2019026065A2 (en) * 2017-07-29 2019-02-07 Lutris Pharma Ltd. NOVEL BRAF INHIBITORS AND THEIR USE FOR THE TREATMENT OF SKIN REACTIONS
WO2019070920A1 (en) * 2017-10-03 2019-04-11 Collidion, Inc. COMPOSITIONS, METHODS AND USES FOR ENHANCING A ZONE OF SKIN OR HAIR
IL285560B2 (en) * 2019-02-12 2024-04-01 Lutris Pharma Ltd Topical preparations containing a BRAF inhibitor for the treatment of dermatitis as a result of radiation

Also Published As

Publication number Publication date
ES3060285T3 (en) 2026-03-25
MX2023007547A (es) 2023-08-10
EP4267144A4 (en) 2024-10-23
WO2022136912A1 (en) 2022-06-30
CN116669739A (zh) 2023-08-29
EP4267144B1 (en) 2025-12-31
CA3203021A1 (en) 2022-06-30
IL303804A (en) 2023-08-01
US20230321106A1 (en) 2023-10-12
EP4267144A1 (en) 2023-11-01

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