DK4288547T3 - Aptamerer til brug i behandlingen af coronaviridae-infektioner - Google Patents

Aptamerer til brug i behandlingen af coronaviridae-infektioner Download PDF

Info

Publication number
DK4288547T3
DK4288547T3 DK22716269.0T DK22716269T DK4288547T3 DK 4288547 T3 DK4288547 T3 DK 4288547T3 DK 22716269 T DK22716269 T DK 22716269T DK 4288547 T3 DK4288547 T3 DK 4288547T3
Authority
DK
Denmark
Prior art keywords
aptamers
treatment
coronaviridae infections
coronaviridae
infections
Prior art date
Application number
DK22716269.0T
Other languages
English (en)
Inventor
Annekathrin Haberland
JOHANNES MüLLER
Gerd Wallukat
Peter Göttel
Original Assignee
Berlin Cures GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2021/059328 external-priority patent/WO2021205012A1/en
Application filed by Berlin Cures GmbH filed Critical Berlin Cures GmbH
Application granted granted Critical
Publication of DK4288547T3 publication Critical patent/DK4288547T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/16Aptamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK22716269.0T 2021-04-09 2022-04-08 Aptamerer til brug i behandlingen af coronaviridae-infektioner DK4288547T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2021/059328 WO2021205012A1 (en) 2020-04-09 2021-04-09 Aptamers for use in the treatment of coronaviridae infections
PCT/EP2022/059466 WO2022214670A1 (en) 2021-04-09 2022-04-08 Aptamers for use in the treatment of coronaviridae infections

Publications (1)

Publication Number Publication Date
DK4288547T3 true DK4288547T3 (da) 2025-01-13

Family

ID=81307234

Family Applications (1)

Application Number Title Priority Date Filing Date
DK22716269.0T DK4288547T3 (da) 2021-04-09 2022-04-08 Aptamerer til brug i behandlingen af coronaviridae-infektioner

Country Status (15)

Country Link
US (1) US20240191241A1 (da)
EP (1) EP4288547B1 (da)
JP (2) JP2024509645A (da)
KR (2) KR20260019033A (da)
CN (1) CN117500927A (da)
AU (2) AU2022255586B2 (da)
BR (1) BR112023020893A2 (da)
CA (1) CA3214646C (da)
DK (1) DK4288547T3 (da)
ES (1) ES3007984T3 (da)
IL (1) IL307360B2 (da)
MX (1) MX2023011974A (da)
PL (1) PL4288547T3 (da)
WO (1) WO2022214670A1 (da)
ZA (1) ZA202309185B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116144665B (zh) * 2022-12-30 2024-12-17 中国人民解放军军事科学院军事医学研究院 核酸适配体在特异性识别冠状病毒中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2497828A1 (en) * 2011-03-07 2012-09-12 Charité - Universitätsmedizin Berlin Use of aptamers in therapy and/or diagnosis of autoimmune diseases
IL234246A0 (en) * 2014-08-21 2014-11-30 Omrix Biopharmaceuticals Ltd Stabilized thrombin
CA3044484A1 (en) * 2016-11-23 2018-05-31 Berlin Cures GmbH Aptamers for use in inhibition and/or suppression of tlr9 activation
AU2021252151A1 (en) * 2020-04-09 2022-12-08 Berlin Cures GmbH Aptamers for use in the treatment of coronaviridae infections

Also Published As

Publication number Publication date
JP2024509645A (ja) 2024-03-04
ZA202309185B (en) 2025-01-29
AU2022255586A9 (en) 2023-10-26
PL4288547T3 (pl) 2025-05-12
IL307360B2 (en) 2025-01-01
ES3007984T3 (en) 2025-03-21
IL307360A (en) 2023-11-01
CN117500927A (zh) 2024-02-02
AU2022255586B2 (en) 2024-04-04
KR20230170931A (ko) 2023-12-19
CA3214646C (en) 2024-11-12
KR20260019033A (ko) 2026-02-09
MX2023011974A (es) 2023-10-23
IL307360B1 (en) 2024-09-01
AU2024204344A1 (en) 2024-07-18
CA3214646A1 (en) 2022-10-13
AU2022255586A1 (en) 2023-10-12
WO2022214670A1 (en) 2022-10-13
EP4288547A1 (en) 2023-12-13
US20240191241A1 (en) 2024-06-13
JP2026021387A (ja) 2026-02-10
EP4288547B1 (en) 2024-10-09
BR112023020893A2 (pt) 2024-02-27

Similar Documents

Publication Publication Date Title
DK3641819T3 (da) Anvendelse af cannabidiol i behandling af tuberøst sklerosekompleks
PL3556377T3 (pl) Dalargin do stosowania w leczeniu ostrych infekcji wirusowych dróg oddechowych
PT4327866T (pt) Mirikizumab no tratamento da colite ulcerosa
DK3285809T3 (da) Inhibitorer af immunkontrolpunktsmodulatorer til anvendelse i behandling af kræft og infektioner.
MA42819A (fr) Procédés pour le traitement d'infections virales à arenaviridae et coronaviridae
EP4318286A4 (en) MULTI-PARTY SECURE COMPUTATION
IL271863B (en) Compounds and use thereof for the treatment of microbial infections
PL4356969T3 (pl) Skondensowane trójpierścieniowe związki pirydazynonowe przydatne w leczeniu zakażenia ortomyksowirusami
DK3570940T3 (da) Pridopidin til anvendelse i behandling af fragilt x-syndrom
EP3858943A4 (en) Surface treatment agent
LT3820856T (lt) C-manozido junginiai, naudingi šlapimo takų infekcijoms gydyti
PL4005570T3 (pl) Pridopidyna do zastosowania w leczeniu zespołu retta
DK3388427T3 (da) Derivater af dolastatin 10 og auristatiner
PL3592355T3 (pl) Kx2-391/kx-01 do zastosowania w leczeniu rogowacenia słonecznego
DK4076461T3 (da) Lumateperon til brug ved behandling af skizofreni
PL3478719T3 (pl) Stosowanie przeciwciał przeciw sklerostynie w leczeniu wrodzonej łamliwości kości
DK3576738T3 (da) Gaboxadolmonohydrat i behandling af tinnitus
IL289371A (en) Methylthioninium for use in the treatment of synaptopathies
DK3519411T3 (da) Heterocykliske forbindelser og deres anvendelse inden for forebyggelsen eller behandlingen af bakterieinfektioner
IL281569A (en) Use of tradipitant in motion sickness
IL281775A (en) Methods of treatment of infections using bacteria
PL3850113T3 (pl) Markery przydatne w strategiach wzbogacania przy leczeniu choroby zwyrodnieniowej stawów
LT3405197T (lt) Delgocitinibo panaudojimas lėtinės rankų egzemos gydymui
DK4218788T3 (da) Peptider til anvendelse ved behandling af ikke-alkoholisk steatohepatitis
EP4269468A4 (en) SURFACE TREATMENT AGENT