DK431784A - Oxopyrimidin-derivater og farmaceutiske praeparater som indeholder dem - Google Patents

Oxopyrimidin-derivater og farmaceutiske praeparater som indeholder dem Download PDF

Info

Publication number: DK431784A
Authority: DK; Denmark
Prior art keywords: sub; pharmaceutical preparations; preparations containing; hydrogen; compounds
Prior art date: 1983-09-14

Application number

DK431784A

Other languages

English (en)

Other versions

DK167615B1 (da

DK431784D0 (da

Inventor

Barrie Levitt

Morris Stolar

Original Assignee

Taro Pharma Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-14

Filing date

1984-09-11

Publication date

1985-03-15

1984-09-11 Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind

1984-09-11 Publication of DK431784D0 publication Critical patent/DK431784D0/da

1985-03-15 Publication of DK431784A publication Critical patent/DK431784A/da

1993-11-29 Application granted granted Critical

1993-11-29 Publication of DK167615B1 publication Critical patent/DK167615B1/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000000049 anti-anxiety effect Effects 0.000 abstract 1
230000001773 anti-convulsant effect Effects 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
229960003965 antiepileptics Drugs 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
239000003158 myorelaxant agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK431784A 1983-09-14 1984-09-11 Barbitursyrederivater og farmaceutiske praeparater indeholdende saadanne DK167615B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL69722A IL69722A (en)	1983-09-14	1983-09-14	Oxopyrimidine derivatives and pharmaceutical compositions containing them
IL6972283		1983-09-14

Publications (3)

Publication Number	Publication Date
DK431784D0 DK431784D0 (da)	1984-09-11
DK431784A true DK431784A (da)	1985-03-15
DK167615B1 DK167615B1 (da)	1993-11-29

Family

ID=11054532

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK431784A DK167615B1 (da)	1983-09-14	1984-09-11	Barbitursyrederivater og farmaceutiske praeparater indeholdende saadanne

Country Status (10)

Country	Link
US (1)	US4628056A (da)
EP (1)	EP0137343B1 (da)
JP (1)	JPH0730044B2 (da)
AT (1)	ATE70056T1 (da)
AU (1)	AU571265B2 (da)
DE (1)	DE3485318D1 (da)
DK (1)	DK167615B1 (da)
IE (1)	IE58038B1 (da)
IL (1)	IL69722A (da)
ZA (1)	ZA847274B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0223037A1 (de) *	1985-10-24	1987-05-27	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Phenylbarbitursäuren und deren Herstellung
US6093820A (en) *	1997-10-02	2000-07-25	Taro Pharmaceutical Industries Ltd.	Method and reagents for N-alkylating ureides
CA2306170A1 (en) *	2000-04-18	2001-10-18	Kenneth Curry	Novel amino, carboxy derivatives of barbituric acid
US6756379B2 (en) *	2001-07-26	2004-06-29	Taro Pharmaceutical Industries Ltd.	Non-sedating barbiturate compounds as neuroprotective agents
EP1905441A3 (en) *	2000-07-26	2008-04-23	Taro Pharmaceutical Industries Limited	Non-sedating barbiturate compounds as neuroprotective agents
DE60132337T2 (de) *	2000-07-26	2009-02-12	Taro Pharmaceutical Industries Ltd.	Nicht-sedierende barbituratverbindungen als neuroprotektive wirkstoffe
AU2007200460B2 (en) *	2000-07-26	2009-10-08	Taro Pharmaceutical Industries Ltd.	Non-sedating barbiturate compounds as neuroprotective agents
US6939873B2 (en) *	2000-07-26	2005-09-06	Taro Pharmaceuticals Industries Limited	Non-sedating barbituric acid derivatives
US7683071B2 (en) *	2000-07-26	2010-03-23	Taro Pharmaceuticals Industries Ltd.	Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
RU2196579C2 (ru) *	2001-02-08	2003-01-20	Амурская государственная медицинская академия	Способ снижения уровня тревожности у лабораторных животных в эксперименте
EP1485101A4 (en) *	2002-01-30	2006-04-12	Taro Pharma Ind	NON-SURFACTANT BARBITIC ACID DERIVATIVES
US6810318B2 (en) *	2002-09-13	2004-10-26	General Motors Corporation	Drive torque transfer scheme
ES2315569T3 (es) *	2002-12-11	2009-04-01	Taro Pharmaceutical Industries Ltd.	Procedimiento de tratamiento de trastornos del movimiento usando derivados de acido barbiturico.
CA2572797A1 (en) *	2004-07-02	2006-01-12	Daniella Gutman	A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid
EP1625848A1 (en) *	2004-08-10	2006-02-15	Taro Pharmaceuticals North America, Inc.	Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid
EP2081576A4 (en) *	2006-11-14	2010-06-30	Taro Pharmaceuticals North Ame	METHOD FOR IMPROVING BIOAVAILABILITY FOR NON-EDMING BARBITURATES
US9056817B2 (en) *	2011-09-12	2015-06-16	Council Of Scientific And Industrial Research	Arylated β-dicarbonyl compounds and process for the preparation thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1960170A (en) *		1934-05-22		Cc - phenylethyl - n -
US3930006A (en) *	1963-04-30	1975-12-30	Aspro Nicholas Ltd	Antiparkinsonism compositions and method
US4046894A (en) *	1968-08-05	1977-09-06	Bristol-Myers Company	Certain barbituric acid derivatives used as anticonvulsant agents
US3919427A (en) *	1972-06-02	1975-11-11	Kendall & Co	Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds
US3948896A (en) *	1973-02-28	1976-04-06	The Kendall Company	N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same

1983
- 1983-09-14 IL IL69722A patent/IL69722A/xx not_active IP Right Cessation
1984
- 1984-09-05 US US06/647,680 patent/US4628056A/en not_active Expired - Lifetime
- 1984-09-10 AU AU32875/84A patent/AU571265B2/en not_active Ceased
- 1984-09-11 DK DK431784A patent/DK167615B1/da not_active IP Right Cessation
- 1984-09-13 EP EP84110959A patent/EP0137343B1/en not_active Expired - Lifetime
- 1984-09-13 JP JP19241384A patent/JPH0730044B2/ja not_active Expired - Lifetime
- 1984-09-13 DE DE8484110959T patent/DE3485318D1/de not_active Expired - Lifetime
- 1984-09-13 IE IE233284A patent/IE58038B1/en not_active IP Right Cessation
- 1984-09-13 AT AT84110959T patent/ATE70056T1/de not_active IP Right Cessation
- 1984-09-14 ZA ZA847274A patent/ZA847274B/xx unknown

Also Published As

Publication number	Publication date
AU571265B2 (en)	1988-04-14
IE58038B1 (en)	1993-06-16
DE3485318D1 (de)	1992-01-16
ZA847274B (en)	1986-04-30
DK167615B1 (da)	1993-11-29
IL69722A (en)	1986-09-30
DK431784D0 (da)	1984-09-11
ATE70056T1 (de)	1991-12-15
EP0137343A3 (en)	1986-06-11
JPS6084272A (ja)	1985-05-13
JPH0730044B2 (ja)	1995-04-05
EP0137343A2 (en)	1985-04-17
EP0137343B1 (en)	1991-12-04
US4628056A (en)	1986-12-09
IL69722A0 (en)	1983-12-30
IE842332L (en)	1985-03-14
AU3287584A (en)	1985-03-21

Legal Events

Date	Code	Title	Description
1993-11-29	B1	Patent granted (law 1993)
2004-09-27	PUP	Patent expired

Publication	Publication Date	Title
DK431784D0 (da)	1984-09-11	Oxopyrimidin-derivater og farmaceutiske praeparater som indeholder dem
AU543054B2 (en)	1985-03-28	Heterocyclic amine derivatives
DK1093819T3 (da)	2006-09-11	Forbindelse og præparat til tilförsel af aktive midler
DK0530087T3 (da)	1995-10-02	Hidtil ukendte naphthylethylurinstof- og naphthylethylthiourinstofforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
NO180538C (no)	1997-05-07	N-sulfonyl-2-oksoindol-derivater som har affinitet for vasopressin- og/eller ocytocin-reseptorer, farmasöytiske blandinger som inneholder dem og mellomprodukter ved fremstilling av derivatene
ID27124A (id)	2001-03-01	Penghambat kinase bisiklik
TR200001603T2 (tr)	2000-10-23	Yeni bileşikler
PT758248E (pt)	2003-11-28	Formulacoes para o factor ix
MX9700557A (es)	1997-12-31	Dihidrobenzofuranos.
NO20006323D0 (no)	2000-12-12	Glykopeptidderivater og farmasöytiske sammensetninger som inneholder disse
NO904595D0 (no)	1990-10-24	Fremgangsmaate for potensiering av den analgetiske effekt av curcuminoid.
DE69811062D1 (de)	2003-03-06	Polyaromatische antivirale zusammensetzungen
ATE180781T1 (de)	1999-06-15	Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
ES2001106A6 (es)	1988-04-16	Procedimiento para la obtencion de 1-aril-pirazoles
ES8505927A1 (es)	1985-06-16	Procedimiento para la preparacion de derivados de 1-(fenil)-1-hidroxi-2-amino-3-fluoro-propano
IS4367A (is)	1996-09-30	CCK eða gastrín temprandi 5-heterósýklísk-1,5-bensódíazepín
DK1056771T3 (da)	2006-04-03	Streptograminderivater, deres fremstilling og præparater, der indeholder dem
DK0490816T3 (da)	1997-09-22	Fluorforbindelser som aromatase-inhibitorer.
MX9702203A (es)	1997-06-28	Derivados de pirazolil-pirazol substituidos, procedimientos para su preparacion y su uso como agentes con accion herbicida.
DK415789A (da)	1990-02-27	Tetracykliske antidepressive midler
SE8302751L (sv)	1983-11-19	2(1h)-pyridinonderivat, deras framstellning och farmaceutiska beredningar som innehaller dem
DK259589D0 (da)	1989-05-26	Joderede, ikke-ioniske trijodbenzenforbindelser og kontrastmiddel indeholdende dem
DE59303446D1 (de)	1996-09-19	Neue bis-phenyl-hexene
ATE204847T1 (de)	2001-09-15	Tetracyclische aromatische retinoide verbindungen,ihre herstellung und verwendung
AU590200B2 (en)	1989-11-02	Aroyl substituted dihydro-1,4-thiazines