DK433484A - Medikamentholdigt lipidvesikelpraeparat - Google Patents

Medikamentholdigt lipidvesikelpraeparat Download PDF

Info

Publication number
DK433484A
DK433484A DK433484A DK433484A DK433484A DK 433484 A DK433484 A DK 433484A DK 433484 A DK433484 A DK 433484A DK 433484 A DK433484 A DK 433484A DK 433484 A DK433484 A DK 433484A
Authority
DK
Denmark
Prior art keywords
vesical
preparation
lipid
medicinal
medicinal lipid
Prior art date
Application number
DK433484A
Other languages
English (en)
Other versions
DK165219B (da
DK433484D0 (da
DK165219C (da
Inventor
Hiromitsu Yoshida
Jiro Fujisaki
Seiji Sawai
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK433484D0 publication Critical patent/DK433484D0/da
Publication of DK433484A publication Critical patent/DK433484A/da
Publication of DK165219B publication Critical patent/DK165219B/da
Application granted granted Critical
Publication of DK165219C publication Critical patent/DK165219C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK433484A 1983-09-12 1984-09-11 Medikamentholdigt lipidvesikelpraeparat og fremgangsmaade til fremstilling deraf DK165219C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58168824A JPS6058915A (ja) 1983-09-12 1983-09-12 薬物含有脂質小胞体製剤
JP16882483 1983-09-12

Publications (4)

Publication Number Publication Date
DK433484D0 DK433484D0 (da) 1984-09-11
DK433484A true DK433484A (da) 1985-03-13
DK165219B DK165219B (da) 1992-10-26
DK165219C DK165219C (da) 1993-03-22

Family

ID=15875191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK433484A DK165219C (da) 1983-09-12 1984-09-11 Medikamentholdigt lipidvesikelpraeparat og fremgangsmaade til fremstilling deraf

Country Status (6)

Country Link
US (1) US4743449A (da)
EP (1) EP0140085B1 (da)
JP (1) JPS6058915A (da)
AT (1) ATE52411T1 (da)
DE (1) DE3482161D1 (da)
DK (1) DK165219C (da)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897308A (en) * 1975-06-30 1990-01-30 L'oreal Compositions comprising aqueous dispersions of lipid spheres
GB8522963D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Microcapsules
JPS6295134A (ja) * 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk リポソ−ムの製造法
US4849227A (en) * 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
DE3750369T2 (de) * 1986-03-21 1995-05-24 Eurasiam Lab Arzneimittelzusammensetzungen.
AU598002B2 (en) * 1986-07-15 1990-06-14 Cilag Ltd. Method of preparing single bilayered liposomes
NZ221411A (en) * 1986-08-11 1989-10-27 Innovata Biomed Ltd Pharmaceutical compositions containing microcapsules and a surfactant
CA1321351C (en) * 1987-02-23 1993-08-17 Helmut Otmar Hauser Method of dehydrating vesicle preparations for long-term storage
US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
DK86988A (da) * 1987-02-25 1988-08-26 Takeda Chemical Industries Ltd Liposompraeparat og anvendelse deraf
US5219538A (en) * 1987-03-13 1993-06-15 Micro-Pak, Inc. Gas and oxygen carrying lipid vesicles
JP2550352B2 (ja) * 1987-06-26 1996-11-06 第一製薬株式会社 リポソ−ム製剤
MX9203804A (es) * 1987-10-19 1992-07-01 Liposome Co Inc Sistemas farmaceuticos a base de tocoferol.
JP2643217B2 (ja) * 1988-01-22 1997-08-20 エーザイ株式会社 脂溶性物質水性液
JPH0720857B2 (ja) * 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
US6132763A (en) * 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
US5165994A (en) * 1990-06-05 1992-11-24 University Of Delaware Spontaneous equilbrium surfactant vesicles
EP0577751B1 (en) * 1991-03-28 1998-11-11 Micro-Pak, Inc. Lipid vesicle containing water-in-oil emulsions
US5256422A (en) * 1991-03-28 1993-10-26 Micro Vesicular Systems, Inc. Lipid vesicle containing water-in-oil emulsions
DE4121945C2 (de) * 1991-07-03 1993-11-04 Merz & Co Gmbh & Co Verfahren zur herstellung von stabilen, hydrophilen oder ambiphilen creme-zubereitungen, enthaltend vesikulaere bestandteile, stabile creme-zubereitungen mit vesikulaeren bestandteilen und deren verwendung
US5439967A (en) * 1991-09-17 1995-08-08 Micro Vesicular Systems, Inc. Propylene glycol stearate vesicles
ES2041597B1 (es) * 1992-05-05 1994-06-01 Bazaco Joan Freixas Nuevo procedimiento para la preparacion de liposomas que encapsulan productos farmaceuticos y cosmeticos.
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
US5514670A (en) * 1993-08-13 1996-05-07 Pharmos Corporation Submicron emulsions for delivery of peptides
GB9323588D0 (en) * 1993-11-16 1994-01-05 Cortecs Ltd Hydrophobic preparation
DE4343833A1 (de) * 1993-12-22 1995-06-29 Beiersdorf Ag W/O/W-Emulsionen
US5858398A (en) * 1994-11-03 1999-01-12 Isomed Inc. Microparticular pharmaceutical compositions
US5902604A (en) 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
US6231900B1 (en) 1995-08-19 2001-05-15 The Procter & Gamble Company Confectionery product and preparation thereof
US6132789A (en) * 1995-12-15 2000-10-17 National Research Council Of Canada Archaeosomes, archaeosomes containing coenzyme Q10, and other types of liposomes containing coenzyme Q10 as adjuvants and as delivery vehicles
DE19647352C2 (de) * 1996-11-15 2000-06-29 Aqua Nova Getraenketechnologie Nicht alkoholisches Getränk mit einem Gehalt an Q 10
DE69819145T2 (de) * 1997-04-17 2004-08-19 Amgen Inc., Thousand Oaks Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung
GB9707979D0 (en) 1997-04-21 1997-06-11 Procter & Gamble Confectionery compositions
GB9707977D0 (en) 1997-04-21 1997-06-11 Procter & Gamble Centre filled confectionery
GB9707978D0 (en) 1997-04-21 1997-06-11 Procter & Gamble Throat soothing compositions
US20020103165A1 (en) * 2000-02-29 2002-08-01 Alliance Pharmaceutical Corp., Engineered spray-dried lipid-based microparticles for cellular targeting
DE10117043A1 (de) * 2001-04-05 2002-11-07 Gerhard Puetz Verfahren zur Eliminierung von potentiell toxischen und/oder schädlichen Stoffen
KR100439068B1 (ko) * 2001-09-07 2004-07-05 주식회사 코리아나화장품 레티놀을 3중으로 안정화한 화장료
US20040018237A1 (en) 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
JP2007261984A (ja) * 2006-03-28 2007-10-11 Konica Minolta Medical & Graphic Inc 脂肪酸エステルを有するリポソ−ムおよびその製剤
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
HUE031951T2 (en) * 2006-10-10 2017-08-28 Jina Pharmaceuticals Inc Aqueous systems for lipid-based drug compounds; preparations, processes and their use
WO2008133908A2 (en) 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
TWI492759B (zh) 2008-03-05 2015-07-21 Otsuka Pharma Co Ltd 膽甾烷醇衍生物之併用用途
PT2404608E (pt) 2009-03-04 2015-07-21 Otsuka Pharma Co Ltd Derivado de colestanol para utilização combinada
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
CN103547258B (zh) 2011-03-17 2017-10-20 特兰斯德梅尔生物工艺股份有限公司 局部一氧化氮系统及其使用方法
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru) 2015-06-03 2020-08-26 Интарсия Терапьютикс, Инк. Системы установки и извлечения имплантата
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
JP7286542B2 (ja) 2017-01-03 2023-06-05 インターシア セラピューティクス，インコーポレイティド Ｇｌｐ－１受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
EP4188552A2 (en) 2020-07-28 2023-06-07 Jazz Pharmaceuticals Ireland Limited Fused bicyclic raf inhibitors and methods for use thereof
IL300110A (en) 2020-07-28 2023-03-01 Jazz Pharmaceuticals Ireland Ltd Chiral synthesis of fused bicyclic raf inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356167A (en) * 1978-01-27 1982-10-26 Sandoz, Inc. Liposome drug delivery systems
US4201767A (en) * 1978-11-08 1980-05-06 Merck & Co., Inc. Viral liposome particle
US4235877A (en) * 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
EP0102324A3 (de) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤
JPS607932A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes

Also Published As

Publication number Publication date
DK165219B (da) 1992-10-26
DK433484D0 (da) 1984-09-11
EP0140085B1 (en) 1990-05-09
EP0140085A2 (en) 1985-05-08
DK165219C (da) 1993-03-22
DE3482161D1 (de) 1990-06-13
JPH0559087B2 (da) 1993-08-30
JPS6058915A (ja) 1985-04-05
EP0140085A3 (en) 1986-08-06
ATE52411T1 (de) 1990-05-15
US4743449A (en) 1988-05-10

Similar Documents

Publication Publication Date Title
DK433484A (da) Medikamentholdigt lipidvesikelpraeparat
NO172729C (no) Fremgangsmaate for fremstilling av en suspensjon av fosfolipidvesikler.
DE3867637D1 (de) Paucilamellare lipidvesikel.
GB8501015D0 (en) Drug
ATE141166T1 (de) Guanidinaminoglycosid enthaltende liposome
RU95101387A (ru) Концентрированный водный раствор аргатробана
ES534598A0 (es) Un procedimiento para preparar una solucion acuosa que contiene una sustancia farmaceutica soluble en lipidos
SE8206168D0 (sv) Preparations and process for preparation thereof
ES508174A0 (es) "un procedimiento para obtener vesiculas".
FI940993A0 (fi) Salisyylihapon kosmeettinen jakelujärjestelmä ja menetelmä tämän valmistamiseksi
AU7285987A (en) For facilitating the formation of lipid spherules dispersed in an aqueous phase and for improving their stability and their degree of encapsulation, and corresponding dispersions
ES8704755A1 (es) Un metodo para cargar liposomas con un agente bioactivo ionizable
ES2152324T3 (es) Vesiculas lipidicas multilaminares bifasicas.
ES2054053T3 (es) Procedimiento de preparacion de sistemas coloidales dispersables de lipidos amfifilos en forma de liposomas submicronicos.
EP0728476A4 (en) LIPOSOME COMPOSITION
DE3586095D1 (de) Herstellung von lipid-vesikeln.
MX5837E (es) Procedimiento para la preparacion de una emulsion insecticida de aceite en agua
KR920002165A (ko) 리포좀 생성물
DE3361768D1 (en) Phospholipid solutions
HUT62457A (en) Process for producing aqueous liposomal suspensions comprising an active ingredient
ATE101512T1 (de) Oeliges ketoprofen enthaltende kapsel.
IT1164363B (it) Procedimento terapeutico facente uso di liposomi imcorporati fruttosio 1,6 difosfato e procedimento per la preparazione degli stessi
MX9203411A (es) Microcristales que comprenden una substancia activa que tiene una afinidad por los fosfolipidos y por lo menos un fosfolipido, proceso de preparacion
ATE99168T1 (de) Rekonstituierungsverfahren.

Legal Events

Date Code Title Description
PBP Patent lapsed