DK433685A - Fremgangsmaade til regenerering af 6-flour-4-chromanon fra (r)-6-fluor-4-ureidochrom-4-carboxylsyre eller en blanding af denne og (rs)-forbindelsen - Google Patents
Fremgangsmaade til regenerering af 6-flour-4-chromanon fra (r)-6-fluor-4-ureidochrom-4-carboxylsyre eller en blanding af denne og (rs)-forbindelsen Download PDFInfo
- Publication number
- DK433685A DK433685A DK433685A DK433685A DK433685A DK 433685 A DK433685 A DK 433685A DK 433685 A DK433685 A DK 433685A DK 433685 A DK433685 A DK 433685A DK 433685 A DK433685 A DK 433685A
- Authority
- DK
- Denmark
- Prior art keywords
- carboxylic acid
- fluoro
- ureidochrome
- chromanon
- fluor
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
- PLFOGGJHQOVQAF-LLVKDONJSA-N (4r)-4-(carbamoylamino)-6-fluoro-2,3-dihydrochromene-4-carboxylic acid Chemical compound C1=C(F)C=C2[C@@](NC(=O)N)(C(O)=O)CCOC2=C1 PLFOGGJHQOVQAF-LLVKDONJSA-N 0.000 abstract 3
- SWBBIJZMIGAZHW-UHFFFAOYSA-N 6-fluoro-2,3-dihydrochromen-4-one Chemical compound O1CCC(=O)C2=CC(F)=CC=C21 SWBBIJZMIGAZHW-UHFFFAOYSA-N 0.000 abstract 3
- 230000004048 modification Effects 0.000 abstract 2
- 238000012986 modification Methods 0.000 abstract 2
- LXANPKRCLVQAOG-NSHDSACASA-N sorbinil Chemical compound C12=CC(F)=CC=C2OCC[C@@]21NC(=O)NC2=O LXANPKRCLVQAOG-NSHDSACASA-N 0.000 abstract 2
- 229950004311 sorbinil Drugs 0.000 abstract 2
- 229940118148 Aldose reductase inhibitor Drugs 0.000 abstract 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000012286 potassium permanganate Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/54—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 substituted in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Jellies, Jams, And Syrups (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Manufacture, Treatment Of Glass Fibers (AREA)
- Control And Safety Of Cranes (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/655,006 US4551542A (en) | 1984-09-26 | 1984-09-26 | Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid |
| CN85106603.8A CN1004000B (zh) | 1984-09-26 | 1985-08-31 | 由6-氟代-4-脲基苯并二氢吡喃-4-羧酸再生为6-氟代苯并二氢吡喃-4-酮的方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK433685D0 DK433685D0 (da) | 1985-09-25 |
| DK433685A true DK433685A (da) | 1986-03-27 |
Family
ID=76224744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK433685A DK433685A (da) | 1984-09-26 | 1985-09-25 | Fremgangsmaade til regenerering af 6-flour-4-chromanon fra (r)-6-fluor-4-ureidochrom-4-carboxylsyre eller en blanding af denne og (rs)-forbindelsen |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4551542A (da) |
| EP (1) | EP0179570B1 (da) |
| JP (1) | JPS6185376A (da) |
| KR (1) | KR870000584B1 (da) |
| CN (1) | CN1004000B (da) |
| AT (1) | ATE36158T1 (da) |
| AU (1) | AU554303B2 (da) |
| CA (1) | CA1215378A (da) |
| DD (1) | DD239594A5 (da) |
| DE (1) | DE3564111D1 (da) |
| DK (1) | DK433685A (da) |
| ES (1) | ES8604848A1 (da) |
| FI (1) | FI853684A7 (da) |
| GR (1) | GR852286B (da) |
| HU (1) | HU196387B (da) |
| IL (1) | IL76488A (da) |
| NO (1) | NO853769L (da) |
| PH (1) | PH20691A (da) |
| PL (1) | PL147214B1 (da) |
| PT (1) | PT81184B (da) |
| SU (1) | SU1340586A3 (da) |
| YU (1) | YU43885B (da) |
| ZA (1) | ZA857379B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11498018B2 (en) * | 2017-11-27 | 2022-11-15 | Vasilios (Bill) Panagiotakopoulos | Extraction and purification of cannabinoid compounds |
| CN112939793B (zh) * | 2021-02-03 | 2022-07-08 | 浙江普洛康裕制药有限公司 | 麻黄碱和伪麻黄碱工业生产过程中母液中活性成分的回收利用方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4210663A (en) * | 1978-11-08 | 1980-07-01 | Pfizer Inc. | Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids |
| US4348526A (en) * | 1980-03-28 | 1982-09-07 | Pfizer Inc. | Intermediates in the preparation of chiral hydantoins |
| US4286098A (en) * | 1980-03-28 | 1981-08-25 | Pfizer Inc. | Process for the preparation of chiral hydantoins |
| DE3262294D1 (en) * | 1981-05-13 | 1985-03-28 | Ici Plc | Pharmaceutical compositions containing spiro succinimide derivatives |
| US4431828A (en) * | 1982-11-10 | 1984-02-14 | Pfizer Inc. | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil |
| US4435578A (en) * | 1982-11-10 | 1984-03-06 | Pfizer Inc. | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
-
1984
- 1984-09-26 US US06/655,006 patent/US4551542A/en not_active Expired - Lifetime
-
1985
- 1985-06-27 CA CA000485501A patent/CA1215378A/en not_active Expired
- 1985-08-31 CN CN85106603.8A patent/CN1004000B/zh not_active Expired
- 1985-09-19 GR GR852286A patent/GR852286B/el unknown
- 1985-09-23 EP EP85306741A patent/EP0179570B1/en not_active Expired
- 1985-09-23 AT AT85306741T patent/ATE36158T1/de not_active IP Right Cessation
- 1985-09-23 DE DE8585306741T patent/DE3564111D1/de not_active Expired
- 1985-09-24 ES ES547256A patent/ES8604848A1/es not_active Expired
- 1985-09-24 IL IL76488A patent/IL76488A/xx unknown
- 1985-09-24 PT PT81184A patent/PT81184B/pt unknown
- 1985-09-24 DD DD85280951A patent/DD239594A5/de not_active IP Right Cessation
- 1985-09-24 PL PL1985255500A patent/PL147214B1/pl unknown
- 1985-09-25 FI FI853684A patent/FI853684A7/fi not_active IP Right Cessation
- 1985-09-25 DK DK433685A patent/DK433685A/da not_active Application Discontinuation
- 1985-09-25 KR KR1019850007042A patent/KR870000584B1/ko not_active Expired
- 1985-09-25 AU AU47884/85A patent/AU554303B2/en not_active Ceased
- 1985-09-25 PH PH32850A patent/PH20691A/en unknown
- 1985-09-25 SU SU853952444A patent/SU1340586A3/ru active
- 1985-09-25 HU HU853644A patent/HU196387B/hu not_active IP Right Cessation
- 1985-09-25 ZA ZA857379A patent/ZA857379B/xx unknown
- 1985-09-25 NO NO853769A patent/NO853769L/no unknown
- 1985-09-25 YU YU1531/85A patent/YU43885B/xx unknown
- 1985-09-26 JP JP60213619A patent/JPS6185376A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |