DK444281A - Nyt laegemiddel paa basis af 2-amino-6-trifluormethoxybenzothiazol - Google Patents

Nyt laegemiddel paa basis af 2-amino-6-trifluormethoxybenzothiazol

Info

Publication number
DK444281A
DK444281A DK444281A DK444281A DK444281A DK 444281 A DK444281 A DK 444281A DK 444281 A DK444281 A DK 444281A DK 444281 A DK444281 A DK 444281A DK 444281 A DK444281 A DK 444281A
Authority
DK
Denmark
Prior art keywords
trifluormethoxybenzothiazol
amino
new medicine
medicine based
new
Prior art date
Application number
DK444281A
Other languages
Danish (da)
English (en)
Inventor
J Mizoule
Original Assignee
Pharmindustrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmindustrie filed Critical Pharmindustrie
Publication of DK444281A publication Critical patent/DK444281A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)
DK444281A 1980-10-17 1981-10-07 Nyt laegemiddel paa basis af 2-amino-6-trifluormethoxybenzothiazol DK444281A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8022218A FR2492258A1 (fr) 1980-10-17 1980-10-17 Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole

Publications (1)

Publication Number Publication Date
DK444281A true DK444281A (da) 1982-04-18

Family

ID=9247013

Family Applications (1)

Application Number Title Priority Date Filing Date
DK444281A DK444281A (da) 1980-10-17 1981-10-07 Nyt laegemiddel paa basis af 2-amino-6-trifluormethoxybenzothiazol

Country Status (16)

Country Link
US (1) US4370338A (lt)
EP (1) EP0050551B1 (lt)
JP (1) JPS5795910A (lt)
AR (1) AR227069A1 (lt)
AU (1) AU545437B2 (lt)
CA (1) CA1166159A (lt)
DE (1) DE3163230D1 (lt)
DK (1) DK444281A (lt)
FR (1) FR2492258A1 (lt)
GR (1) GR75804B (lt)
HU (1) HU184893B (lt)
IL (1) IL63880A0 (lt)
MA (1) MA19364A1 (lt)
NO (1) NO813492L (lt)
PT (1) PT73828B (lt)
ZA (1) ZA817187B (lt)

Families Citing this family (70)

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US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FR2619713B1 (fr) * 1987-08-25 1990-08-31 Rhone Poulenc Sante Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement des troubles du sommeil et de la depression
FR2619712B1 (fr) * 1987-08-25 1990-08-31 Rhone Poulenc Sante Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la schizophrenie
FR2649705B2 (fr) * 1989-07-13 1994-09-23 Rhone Poulenc Sante Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
FR2649703B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procedes de preparation et les medicaments les contenant
FR2640623B1 (fr) * 1988-12-15 1991-03-22 Rhone Poulenc Sante Derives de la benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR2649701B2 (fr) * 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
ES2043070T3 (es) * 1988-12-15 1993-12-16 Rhone Poulenc Sante Procedimiento para la preparacion de derivados de la benzotiazolamina-2.
US5236940A (en) * 1988-12-15 1993-08-17 Rhone-Poulenc Sante Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation
FR2640622B1 (fr) * 1988-12-15 1991-03-22 Rhone Poulenc Sante Derives de l'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR2640624B1 (fr) * 1988-12-15 1994-08-12 Rhone Poulenc Sante Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
EP0375510B1 (fr) * 1988-12-15 1992-11-11 Rhone-Poulenc Sante Dérivés d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procédés de préparation et les médicaments les contenant
FR2649702B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
EP0409692B1 (fr) * 1989-07-13 1994-03-09 Rhone-Poulenc Sante Dérivés d'imino-2 hétérocyclylalkyl-3 benzothiazoline, leur préparation et les médicaments les contenant
FR2661910B1 (fr) * 1990-05-11 1992-08-21 Rhone Poulenc Sante Derives d'imino-2 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.
FR2649704B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 ethyl-3 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
FR2662160B1 (fr) * 1990-05-18 1992-07-24 Rhone Poulenc Sante Derives d'alkylthio-3 propyl-3 benzothiazoline leur preparation et les medicaments les contenant.
FR2663030A1 (fr) * 1990-06-05 1991-12-13 Rhone Poulenc Sante Derives selenies de benzothiazoline leur preparation et les medicaments les contenant.
FR2662695A1 (fr) * 1990-06-05 1991-12-06 Rhone Poulenc Sante Amino-2 polyfluoroalcoxy-6 benzoselenazoles, leur preparation et les medicaments les contenant.
FR2662694A1 (fr) * 1990-06-05 1991-12-06 Rhone Poulenc Sante Derives du benzoselenazole, leur preparation et les medicaments les contenant.
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
FR2700116B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application d'anticonvulsivants comme radioprotecteurs.
FR2700117B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
FR2702148B1 (fr) * 1993-03-05 1995-04-07 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement du neuro-sida.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2786101B1 (fr) 1998-11-24 2002-07-05 Aventis Laboratoire Utilisation de la nicergoline dans le traitement de la spasticite
FR2787028B1 (fr) 1998-12-15 2002-10-18 Aventis Pharma Sa Utilisation du riluzole dans le traitement des traumatismes acoustiques
CA2361924A1 (en) * 1999-01-12 2000-07-20 Izumi Kamo Compositions for treating frequent urination and urinary incontinence
HRP20030419A2 (en) 2000-11-30 2004-08-31 Pfizer Prod Inc Combination of gaba agonists and aldose reductase inhibitors
IL155704A0 (en) * 2000-11-30 2003-11-23 Pfizer Prod Inc Combination of gaba agonists and sorbitol dehydrogenase inhibitors
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
EP1633400A2 (en) * 2003-05-16 2006-03-15 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
WO2005060968A1 (en) 2003-12-11 2005-07-07 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CA2553291A1 (en) * 2004-01-29 2005-09-09 Pfizer Products Inc. Combination of .gamma.-aminobutyric acid modulators and 5-ht1b receptor antagonists
EP2201963B1 (en) * 2005-04-05 2016-01-27 Yale University Glutamate modulating agents in the treatment of mental disorders
CA2661448A1 (en) 2005-08-25 2007-03-01 Steven Michael Weiss Reducing myocardial damage and the incidence of arrhythmia arising from loss, reduction or interruption in coronary blood flow
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
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US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
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EP2066355A2 (en) * 2006-09-19 2009-06-10 Braincells, Inc. Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080108827A1 (en) * 2006-10-25 2008-05-08 Padi Pratap R Process for preparing riluzole
PL2083811T3 (pl) 2006-11-22 2017-05-31 Clinical Research Associates, Llc Sposoby leczenia zespołu downa, zespołu łamliwego chromosomu x oraz autyzmu
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EP2284161A1 (en) 2009-07-21 2011-02-16 Edmond Pharma S.R.L. Process for the preparation of riluzole
HUE046869T2 (hu) 2014-11-21 2020-04-28 Biohaven Therapeutics Ltd Riluzol szublingvális formulációja
BR112017010440A2 (pt) * 2014-11-21 2017-12-26 Biohaven Pharm Holding Co Ltd administração sublingual de riluzol
KR102279993B1 (ko) 2015-09-23 2021-07-21 엑스더블유파마 리미티드 감마-하이드록시부티르산의 전구체 및 이의 조성물 및 용도
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TW202547822A (zh) 2019-12-20 2025-12-16 香港商凱瑞康寧有限公司 ４－纈胺醯氧基丁酸的合成方法
EP4167966A1 (en) 2020-06-18 2023-04-26 XWPharma Ltd. Pharmaceutical granulations of water-soluble active pharmaceutical ingredients
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CN119970650A (zh) 2020-10-05 2025-05-13 凯瑞康宁生物工程有限公司 γ-羟基丁酸衍生物的修饰释放组合物
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US3879531A (en) * 1972-07-17 1975-04-22 Uniroyal Inc 2-aminothiazoles compositions and methods for using them as psychotherapeutic agents
US3876653A (en) * 1973-03-26 1975-04-08 Kyowa Hakko Kogyo Kk Benzothiazole derivatives

Also Published As

Publication number Publication date
FR2492258A1 (fr) 1982-04-23
JPS5795910A (en) 1982-06-15
CA1166159A (fr) 1984-04-24
US4370338A (en) 1983-01-25
FR2492258B1 (lt) 1982-11-26
DE3163230D1 (en) 1984-05-24
EP0050551A1 (fr) 1982-04-28
IL63880A0 (en) 1981-12-31
HU184893B (en) 1984-10-29
PT73828A (fr) 1981-11-01
AU545437B2 (en) 1985-07-11
NO813492L (no) 1982-04-19
AU7654581A (en) 1982-04-22
GR75804B (lt) 1984-08-02
JPH0148884B2 (lt) 1989-10-20
PT73828B (fr) 1983-01-17
ZA817187B (en) 1982-09-29
AR227069A1 (es) 1982-09-15
MA19364A1 (fr) 1982-07-01
EP0050551B1 (fr) 1984-04-18

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Legal Events

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AHS Application shelved for other reasons than non-payment