DK445986A - Fremgangsmaade og reagens til specifik bestemmelse af hdl-kolesterol i serum - Google Patents

Fremgangsmaade og reagens til specifik bestemmelse af hdl-kolesterol i serum Download PDF

Info

Publication number: DK445986A
Authority: DK; Denmark
Prior art keywords: cholesterol; measurement; bile acid; serum; specific determination
Prior art date: 1985-09-18

Application number

DK445986A

Other languages

English (en)

Other versions

DK445986D0 (da

Inventor

Lorenz Kerscher

Joachim Siedel

Joachim Ziegenhorn

Brigitte Pautz

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-18

Filing date

1986-09-17

Publication date

1987-03-19

1986-09-17 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1986-09-17 Publication of DK445986D0 publication Critical patent/DK445986D0/da

1987-03-19 Publication of DK445986A publication Critical patent/DK445986A/da

Links

HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 10
235000012000 cholesterol Nutrition 0.000 title abstract 5
210000002966 serum Anatomy 0.000 title abstract 3
239000003153 chemical reaction reagent Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 4
108010089254 Cholesterol oxidase Proteins 0.000 abstract 4
238000005259 measurement Methods 0.000 abstract 4
108010055297 Sterol Esterase Proteins 0.000 abstract 3
102000000019 Sterol Esterase Human genes 0.000 abstract 3
CTTJWXVQRJUJQW-UHFFFAOYSA-N 2,2-dioctyl-3-sulfobutanedioic acid Chemical compound CCCCCCCCC(C(O)=O)(C(C(O)=O)S(O)(=O)=O)CCCCCCCC CTTJWXVQRJUJQW-UHFFFAOYSA-N 0.000 abstract 2
229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 2
150000001335 aliphatic alkanes Chemical group 0.000 abstract 2
JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 2
239000003613 bile acid Substances 0.000 abstract 2
239000003599 detergent Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
239000012928 buffer substance Substances 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
238000011534 incubation Methods 0.000 abstract 1
238000006395 oxidase reaction Methods 0.000 abstract 1
230000036284 oxygen consumption Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Endocrinology (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

DK445986A 1985-09-18 1986-09-17 Fremgangsmaade og reagens til specifik bestemmelse af hdl-kolesterol i serum DK445986A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19853533288 DE3533288A1 (de)	1985-09-18	1985-09-18	Verfahren und reagenz zur spezifischen bestimmung von hdl-cholesterin im serum

Publications (2)

Publication Number	Publication Date
DK445986D0 DK445986D0 (da)	1986-09-17
DK445986A true DK445986A (da)	1987-03-19

Family

ID=6281297

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK445986A DK445986A (da)	1985-09-18	1986-09-17	Fremgangsmaade og reagens til specifik bestemmelse af hdl-kolesterol i serum

Country Status (10)

Country	Link
US (1)	US4851335A (da)
EP (1)	EP0218127B1 (da)
JP (1)	JPH0616720B2 (da)
KR (1)	KR890003948B1 (da)
AT (1)	ATE48649T1 (da)
AU (1)	AU574931B2 (da)
DE (2)	DE3533288A1 (da)
DK (1)	DK445986A (da)
ES (1)	ES2001417A6 (da)
FI (1)	FI83975C (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE448324B (sv) *	1985-09-27	1987-02-09	Pharmacia Ab	Sett vid immunkemisk bestemning av lipoproteiner och apolipoproteiner
US5221623A (en) *	1986-07-22	1993-06-22	Boyce Thompson Institute For Plant Research, Inc.	Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
DE3636851A1 (de) *	1986-10-29	1988-05-11	Boehringer Mannheim Gmbh	Verfahren und reagenz zur spezifischen bestimmung des cholesterins der hdl-fraktion
EP0378395B1 (en) *	1989-01-13	1996-08-14	Robert Q. Maines	Method of measuring cholesterol, diagnosing vascular disease, and raising HDL cholesterol levels
US5135716A (en) *	1989-07-12	1992-08-04	Kingston Diagnostics, L.P.	Direct measurement of HDL cholesterol via dry chemistry strips
FI901703A7 (fi) *	1990-04-04	1991-10-05	Elomit Oy	Menetelmä kliinisesti tärkeiden metaboliittien määräämiseksi
US5344571A (en) *	1992-02-18	1994-09-06	University Of Texas System Board Of Regents	Method for separating isoanalytes and measuring analytes in fluids
JP2600065B2 (ja) *	1994-03-08	1997-04-16	協和メデックス株式会社	高密度リポ蛋白中のコレステロールの定量法
JP2653755B2 (ja) *	1994-03-08	1997-09-17	協和メデックス株式会社	高密度リポ蛋白中のコレステロールの定量法
WO1996029599A1 (en) *	1995-03-20	1996-09-26	Kyowa Medex Co., Ltd.	Method of quantifying cholesterol in low-density or very-low-density lipoprotein
US6040151A (en) *	1998-03-10	2000-03-21	Mercury Diagnostics, Inc.	Diagnostic compositions and devices utilizing same
US5776719A (en) *	1997-07-07	1998-07-07	Mercury Diagnostics, Inc.	Diagnostic compositions and devices utilizing same
US5989845A (en)	1996-04-05	1999-11-23	Mercury Diagnostics, Inc.	Diagnostic compositions and devices utilizing same
WO1997040376A1 (fr) *	1996-04-22	1997-10-30	Iatron Laboratories, Inc.	Procede specifique de dosage du cholesterol des lphd et composition utilisee pour le dosage.
JP3193634B2 (ja) *	1996-05-29	2001-07-30	第一化学薬品株式会社	Ｌｄｌコレステロールの定量方法
EP0887422B1 (en) *	1996-12-09	2005-09-14	DENKA SEIKEN Co., Ltd.	Method of determining cholesterol content of high-density lipoproteins
JPH1156395A (ja) *	1997-08-27	1999-03-02	Dai Ichi Pure Chem Co Ltd	コレステロールの定量法
CN100577812C (zh) *	2002-10-16	2010-01-06	协和梅迪克斯株式会社	高密度脂蛋白中的胆固醇的测定方法以及试剂
CN1694964A (zh) *	2002-10-16	2005-11-09	协和梅迪克斯株式会社	高密度脂蛋白中的胆固醇的检测方法及试剂
TWI372783B (en) *	2005-04-27	2012-09-21	Kyowa Medex Co Ltd	A process for measuring the cholesterol in high density lipoprotein
CN100365409C (zh) *	2005-06-01	2008-01-30	王贤理	一种测定低密度脂蛋白胆固醇的试剂及制备方法
GB0609493D0 (en) *	2006-05-12	2006-06-21	Oxford Biosensors Ltd	Cholesterol sensor
GB0609494D0 (en) *	2006-05-12	2006-06-21	Oxford Biosensors Ltd	HDL cholesterol sensor using specific surfactant
JP5332611B2 (ja) *	2007-01-15	2013-11-06	東洋紡株式会社	高密度リポ蛋白中コレステロールの測定方法およびその試薬
JP2014030393A (ja) *	2012-08-03	2014-02-20	Denka Seiken Co Ltd	高密度リポ蛋白（ｈｄｌ）中のコレステロールの定量方法
EP2891718B1 (en)	2012-08-31	2019-01-30	Kyowa Medex Co., Ltd.	Method for measuring cholesterol in high-density lipoprotein
KR102856310B1 (ko) *	2020-12-23	2025-09-05	중앙대학교 산학협력단	다중 효소 나노 입자 기반 콜레스테롤 센서
CN115247161B (zh) *	2021-09-14	2024-06-25	武汉瀚海新酶生物科技有限公司	Genapol X-080用于提高胆固醇酯酶活性的应用和方法
CN114216871B (zh) *	2021-12-15	2024-02-02	青岛汉唐生物科技有限公司	用于胆固醇试剂盒中替代胆酸钠的复合稳定剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4164448A (en) *	1973-12-07	1979-08-14	Boehringer Mannheim Gmbh	Activation of cholesterol oxidase for cholesterol assay
US4184921A (en) *	1976-03-25	1980-01-22	Boehringer Mannheim Gmbh	Process and reagent for determining cholesterol
US4275152A (en) *	1977-02-03	1981-06-23	Eastman Kodak Company	Hydrolysis of protein-bound cholesterol esters
US4205521A (en) *	1977-03-21	1980-06-03	Victoria Torres	Decorative clock
US4105521A (en) *	1977-09-21	1978-08-08	Helena Laboratories Corporation	Clinical procedure for measuring lipoprotein cholesterols
US4226713A (en) *	1978-04-24	1980-10-07	Goldberg Jack M	Diagnostic agents
US4414326A (en) *	1978-04-24	1983-11-08	Goldberg Jack M	Diagnostic agents
DE2963844D1 (en) *	1978-07-04	1982-11-18	Goella Lab	Method and reagents for measuring the cholesterol content in serum
EP0180720B1 (de) *	1981-09-10	1990-06-13	B. Braun-SSC AG	Vorrichtung zur selektiven extrakorporalen Präzipation von Low Density Lipoprotenen aus Vollserum oder Plasma
FR2513766B1 (fr) *	1981-09-28	1985-09-13	Biomerieux Sa	Procedes et reactifs de separation selective des lipoproteines de faible densite ldl et de quantification de leurs composants
DE3208253A1 (de) *	1982-03-08	1983-09-15	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur spezifischen bestimmung des cholesterins der ldl-fraktion im serum
DE3369792D1 (en) *	1982-04-02	1987-03-19	Ivan Endre Modrovich	Improved time-stable liquid cholesterol assay compositions

1985
- 1985-09-18 DE DE19853533288 patent/DE3533288A1/de not_active Withdrawn
1986
- 1986-08-14 AU AU61163/86A patent/AU574931B2/en not_active Ceased
- 1986-09-05 ES ES8601650A patent/ES2001417A6/es not_active Expired
- 1986-09-16 US US06/908,031 patent/US4851335A/en not_active Expired - Lifetime
- 1986-09-17 FI FI863752A patent/FI83975C/fi not_active IP Right Cessation
- 1986-09-17 DK DK445986A patent/DK445986A/da unknown
- 1986-09-17 KR KR1019860007833A patent/KR890003948B1/ko not_active Expired
- 1986-09-18 EP EP86112875A patent/EP0218127B1/de not_active Expired
- 1986-09-18 DE DE8686112875T patent/DE3667492D1/de not_active Expired - Lifetime
- 1986-09-18 JP JP61218274A patent/JPH0616720B2/ja not_active Expired - Lifetime
- 1986-09-18 AT AT86112875T patent/ATE48649T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4851335A (en)	1989-07-25
DE3667492D1 (de)	1990-01-18
FI863752L (fi)	1987-03-19
KR890003948B1 (ko)	1989-10-13
EP0218127B1 (de)	1989-12-13
ATE48649T1 (de)	1989-12-15
JPS6269999A (ja)	1987-03-31
AU574931B2 (en)	1988-07-14
ES2001417A6 (es)	1988-05-16
FI83975C (fi)	1991-09-25
JPH0616720B2 (ja)	1994-03-09
DE3533288A1 (de)	1987-03-26
FI863752A0 (fi)	1986-09-17
DK445986D0 (da)	1986-09-17
KR870003205A (ko)	1987-04-15
FI83975B (fi)	1991-06-14
AU6116386A (en)	1987-03-19
EP0218127A1 (de)	1987-04-15

Publication	Publication Date	Title
DK445986D0 (da)	1986-09-17	Fremgangsmaade og reagens til specifik bestemmelse af hdl-kolesterol i serum
US20090226945A1 (en)	2009-09-10	Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
Noma et al.	1976	Polarographic method for rapid microdetermination of cholesterol with cholesterol esterase and cholesterol oxidase.
US5332678A (en)	1994-07-26	Process for liberating an analyte from its binding protein
EP0636247B1 (en)	1998-09-02	Method and composition for reducing the effects of endogenous alkaline phosphatase
JPH063447B2 (ja)	1994-01-12	化学的触媒の調節剤によるイムノアッセイの信号強化法
US5780239A (en)	1998-07-14	Method for the determination of cast in urine
US5559003A (en)	1996-09-24	Assay method for biological components
US5439799A (en)	1995-08-08	Agent and process for treating body fluids in the determination of neopterin
DE3165392D1 (en)	1984-09-13	Stabilized enzymatic solutions and method for determining total cholesterol in human serum
Björkhem et al.	1982	A simple, fully enzymic bioluminescent assay for triglycerides in serum.
EP0598620A2 (en)	1994-05-25	An analytical system or kit for phosphatase
Xu et al.	1996	Polarographic enzyme-immunoassay for trace hepatitis B surface antigen
EP0398920A1 (en)	1990-11-28	Enzyme labelled biochemical assay for two analytes
EP0399127A1 (en)	1990-11-28	Homogeneous immunochemical method for determining haptens by means of ion selective electrodes
TABATA et al.	1986	Use of phospholipase D and choline oxidase for the enzymatic determination of calcium ion in serum
AU2015202990B2 (en)	2017-11-02	Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
JPH06303996A (ja)	1994-11-01	アルカリホスフォターゼ測定法と測定試薬
Hanson et al.	1983	Enzyme inactivation in serum before determination of total bile acids.
JP2980811B2 (ja)	1999-11-22	アンモニウムイオンの定量方法
Bais et al.	1985	The measurement of oxalate and glycolate with immobilized enzyme systems
Roder et al.	0	STABILIZED ENZYMATIC SOLUTIONS AND METHOD FOR DETERMINING TOTAL CHOLESTEROL IN HUMAN SERUM
GB2095400A (en)	1982-09-29	Detection of enzyme using supported enzyme binder
AU2005202380A1 (en)	2005-06-23	Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
JPH06141893A (ja)	1994-05-24	酵素的測定法