DK446982A - Cyanosteroider og fremgangsmaade til deres fremstilling - Google Patents

Cyanosteroider og fremgangsmaade til deres fremstilling Download PDF

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Publication number
DK446982A
DK446982A DK446982A DK446982A DK446982A DK 446982 A DK446982 A DK 446982A DK 446982 A DK446982 A DK 446982A DK 446982 A DK446982 A DK 446982A DK 446982 A DK446982 A DK 446982A
Authority
DK
Denmark
Prior art keywords
cyanosteroids
procedures
preparation
Prior art date
Application number
DK446982A
Other languages
English (en)
Inventor
George Richard Lenz
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK446982A publication Critical patent/DK446982A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK446982A 1981-10-09 1982-10-08 Cyanosteroider og fremgangsmaade til deres fremstilling DK446982A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/310,204 US4389345A (en) 1981-10-09 1981-10-09 3-Oxoestra-17-acetonitrile and unsaturated analogs

Publications (1)

Publication Number Publication Date
DK446982A true DK446982A (da) 1983-04-10

Family

ID=23201436

Family Applications (1)

Application Number Title Priority Date Filing Date
DK446982A DK446982A (da) 1981-10-09 1982-10-08 Cyanosteroider og fremgangsmaade til deres fremstilling

Country Status (9)

Country Link
US (1) US4389345A (da)
EP (1) EP0077040A1 (da)
JP (1) JPS5872600A (da)
AU (1) AU8923282A (da)
DK (1) DK446982A (da)
ES (1) ES516372A0 (da)
NO (1) NO823374L (da)
PT (1) PT75664B (da)
ZA (1) ZA827381B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724174B1 (fr) * 1994-09-06 1997-01-17 Roussel Uclaf Procede de preparation d'un derive steroide 17beta-carboxy et nouveaux intermediaires
DE10043846A1 (de) * 2000-09-04 2002-04-04 Jenapharm Gmbh 17-Methylensteroide, Verfahren zu deren Herstellung und diese Verbindung enthaltende pharmazeutische Zusammensetzungen
US9388210B2 (en) * 2011-02-25 2016-07-12 Washington University Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
EP4717314A2 (en) 2011-10-14 2026-04-01 Sage Therapeutics, LLC 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
DK2935307T3 (da) 2012-12-18 2018-07-30 Univ Washington Neuroaktive 19-alkoxy-17-substituerede steroider, anvendelige i metoder til behandling
US9512170B2 (en) 2013-03-01 2016-12-06 Washington University Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en) 2013-03-11 2016-06-14 Washington University Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en) 2013-03-14 2017-02-07 Washington University Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SMT202100509T1 (it) 2013-04-17 2021-11-12 Sage Therapeutics Inc Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia
CN117304245A (zh) 2013-04-17 2023-12-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
CA2918735C (en) 2013-07-19 2023-08-01 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN105579043B (zh) 2013-08-23 2021-09-14 萨奇治疗股份有限公司 神经活性类固醇、组合物和其用途
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MY190408A (en) 2014-10-16 2022-04-21 Sage Therapeutics Inc Compositions and methods for treating cns disorders
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
LT3250210T (lt) 2015-01-26 2021-04-12 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti gydyti cns sutrikimus
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
CA3030420C (en) 2016-07-11 2025-11-18 Sage Therapeutics, Inc. C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE
WO2018013613A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
JP7670626B2 (ja) 2019-05-31 2025-04-30 セージ セラピューティクス, インコーポレイテッド 神経刺激性ステロイド及びその組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2336438C2 (de) * 1973-07-14 1983-07-07 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17 β- Oxalylsteroiden

Also Published As

Publication number Publication date
ES8401496A1 (es) 1983-12-16
AU8923282A (en) 1983-04-14
ZA827381B (en) 1983-11-30
NO823374L (no) 1983-04-11
US4389345A (en) 1983-06-21
ES516372A0 (es) 1983-12-16
PT75664B (en) 1985-01-11
EP0077040A1 (en) 1983-04-20
JPS5872600A (ja) 1983-04-30
PT75664A (en) 1982-11-01

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