DK447287D0 - Gaerpromotor, vektor indeholdende en saadan promotor, gaer transformeret med en saadan vektor og fremgangsmaade til fremstilling af et peptid eller protein ved hjaelp af en saadan gaer - Google Patents
Gaerpromotor, vektor indeholdende en saadan promotor, gaer transformeret med en saadan vektor og fremgangsmaade til fremstilling af et peptid eller protein ved hjaelp af en saadan gaerInfo
- Publication number
- DK447287D0 DK447287D0 DK447287A DK447287A DK447287D0 DK 447287 D0 DK447287 D0 DK 447287D0 DK 447287 A DK447287 A DK 447287A DK 447287 A DK447287 A DK 447287A DK 447287 D0 DK447287 D0 DK 447287D0
- Authority
- DK
- Denmark
- Prior art keywords
- promotor
- vector
- activation sequence
- upstream activation
- peptide
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 230000004913 activation Effects 0.000 abstract 5
- 238000011144 upstream manufacturing Methods 0.000 abstract 5
- 101150038242 GAL10 gene Proteins 0.000 abstract 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 2
- 102100024637 Galectin-10 Human genes 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868620926A GB8620926D0 (en) | 1986-08-29 | 1986-08-29 | Yeast promoter |
| GB8620926 | 1986-08-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK447287D0 true DK447287D0 (da) | 1987-08-27 |
| DK447287A DK447287A (da) | 1988-05-20 |
| DK173186B1 DK173186B1 (da) | 2000-03-06 |
Family
ID=10603398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198704472A DK173186B1 (da) | 1986-08-29 | 1987-08-27 | Gærpromotor, vektor indeholdende en sådan promotor, gær transformeret med en sådan vektor og fremgangsmåde til fremstilling |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5739007A (da) |
| EP (1) | EP0258067B1 (da) |
| JP (1) | JP2641457B2 (da) |
| AT (1) | ATE87331T1 (da) |
| AU (1) | AU604257B2 (da) |
| CA (1) | CA1291428C (da) |
| DE (1) | DE3784986T2 (da) |
| DK (1) | DK173186B1 (da) |
| ES (1) | ES2054682T3 (da) |
| FI (1) | FI96620C (da) |
| GB (2) | GB8620926D0 (da) |
| IE (1) | IE59986B1 (da) |
| ZA (1) | ZA876447B (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0245479B1 (en) * | 1985-11-13 | 1993-02-17 | Xoma Corporation | Shortened phosphoglycerate kinase promoter |
| GB8725529D0 (en) * | 1987-10-30 | 1987-12-02 | Delta Biotechnology Ltd | Polypeptides |
| IL89992A0 (en) * | 1988-04-25 | 1989-12-15 | Phillips Petroleum Co | Expression of human serum albumin in methylotrophic yeasts |
| FR2634495B1 (fr) * | 1988-07-01 | 1990-10-26 | Chambon Pierre | Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes |
| FR2649991B2 (fr) * | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| FR2686899B1 (fr) * | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| GB9526733D0 (en) | 1995-12-30 | 1996-02-28 | Delta Biotechnology Ltd | Fusion proteins |
| GB9712370D0 (en) | 1997-06-14 | 1997-08-13 | Aepact Ltd | Therapeutic systems |
| US6926898B2 (en) | 2000-04-12 | 2005-08-09 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20050100991A1 (en) * | 2001-04-12 | 2005-05-12 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20050054051A1 (en) * | 2001-04-12 | 2005-03-10 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US7507413B2 (en) * | 2001-04-12 | 2009-03-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US7176278B2 (en) | 2001-08-30 | 2007-02-13 | Biorexis Technology, Inc. | Modified transferrin fusion proteins |
| WO2003059934A2 (en) | 2001-12-21 | 2003-07-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| WO2005003296A2 (en) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| CA2841097A1 (en) | 2001-12-21 | 2003-07-24 | Human Genome Sciences, Inc. | Albumin and g-csf fusion proteins |
| US20060122374A1 (en) | 2002-02-07 | 2006-06-08 | Peter Mertins | Albumin-fused anti-angiogenesis peptides |
| GB0217033D0 (en) | 2002-07-23 | 2002-08-28 | Delta Biotechnology Ltd | Gene and polypeptide sequences |
| GB0329681D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Gene expression technique |
| US9057061B2 (en) | 2003-12-23 | 2015-06-16 | Novozymes Biopharma Dk A/S | Gene expression technique |
| GB0329722D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Modified plasmid and use thereof |
| CA2552590A1 (en) | 2004-01-05 | 2005-07-21 | Emd Lexigen Research Center Corp. | Interleukin-12 targeted to oncofoetal fibronectin |
| EP2330200B1 (en) | 2004-12-23 | 2017-04-05 | Albumedix A/S | Gene expression technique |
| WO2006138167A1 (en) | 2005-06-14 | 2006-12-28 | Merck & Co., Inc. | Synthetic gene control region |
| DK2046826T3 (da) | 2006-07-24 | 2011-10-24 | Biorexis Pharmaceutical Corp | Exendin-fusionsproteiner |
| WO2008019368A2 (en) | 2006-08-07 | 2008-02-14 | Teva Biopharmaceuticals Usa, Inc. | Albumin-insulin fusion proteins |
| DK2109457T3 (da) | 2007-02-12 | 2016-04-11 | Csl Behring Gmbh | Terapeutisk anvendelse af serinprotease-hæmmere af kazal-type |
| EP2594583A1 (en) | 2007-08-08 | 2013-05-22 | Novozymes Biopharma DK A/S | Transferrin variants and conugates |
| JP2011517410A (ja) * | 2008-04-08 | 2011-06-09 | アミリス バイオテクノロジーズ, インコーポレイテッド | 異種配列の発現 |
| US20110294988A1 (en) | 2009-02-06 | 2011-12-01 | Novozymes Bio Pharma DK A/S | Purification Process |
| SG172789A1 (en) | 2009-02-11 | 2011-08-29 | Novozymes Biopharma Dk As | Albumin variants and conjugates |
| EP2371857A1 (en) | 2010-04-01 | 2011-10-05 | CSL Behring GmbH | Factor XII inhibitors for treating interstitial lung disease |
| AU2012222833B2 (en) | 2011-03-03 | 2017-03-16 | Zymeworks Inc. | Multivalent heteromultimer scaffold design and constructs |
| IN2015DN01115A (da) | 2012-07-13 | 2015-06-26 | Zymeworks Inc | |
| US10239951B2 (en) | 2013-05-08 | 2019-03-26 | Zymeworks Inc. | Bispecific HER2 and HER3 antigen binding constructs |
| CA2874083C (en) | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| EP3394265A1 (en) | 2015-12-23 | 2018-10-31 | Biogen MA Inc. | Dkk2 cysteine rich domain 2 containing proteins and uses thereof |
| MA54070A (fr) | 2018-10-29 | 2021-09-08 | Biogen Ma Inc | Variants fc5 humanisés et stabilisés pour l'amélioration du transport à travers la barrière hémato-encéphalique |
| US12629445B2 (en) | 2020-03-20 | 2026-05-19 | Bard Peripheral Vascular, Inc. | Reactive hydrogel forming formulations and related methods, including methods of preparation |
| CN113462686B (zh) * | 2020-03-30 | 2023-06-02 | 中国科学院深圳先进技术研究院 | 制备具有梯度活性的半乳糖诱导合成启动子的方法、及其制备的启动子、应用 |
| US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
| US12161777B2 (en) | 2020-07-02 | 2024-12-10 | Davol Inc. | Flowable hemostatic suspension |
| WO2022146917A1 (en) | 2020-12-28 | 2022-07-07 | Davol Inc. | Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK368882A (da) * | 1981-08-25 | 1983-02-26 | Alan John Kingsman | Expessions vektorer |
| US4803164A (en) * | 1981-08-31 | 1989-02-07 | Genentech, Inc. | Preparation of hepatitis b surface antigen in yeast |
| US4876197A (en) * | 1983-02-22 | 1989-10-24 | Chiron Corporation | Eukaryotic regulatable transcription |
| GB8314961D0 (en) * | 1983-05-31 | 1983-07-06 | Kingsman A J | Dna sequence |
| EP0480480A3 (en) * | 1984-05-11 | 1992-06-10 | Chiron Corporation | Enhanced yeast transcription employing hybrid promoter region constructs |
| EP0225887B1 (en) * | 1985-04-08 | 1994-06-08 | Amgen Inc. | A method and a hybrid promoter for controlling exogenous gene transcription |
| GB8510219D0 (en) * | 1985-04-22 | 1985-05-30 | Bass Plc | Isolation of fermentation products |
| GB8521496D0 (en) * | 1985-08-29 | 1985-10-02 | Ciba Geigy Ag | Repressible yeast promoters |
| MY101203A (en) * | 1985-12-12 | 1991-08-17 | Ucp Gen Pharma Ag | Production of thrombin iinhibitors. |
-
1986
- 1986-08-29 GB GB868620926A patent/GB8620926D0/en active Pending
-
1987
- 1987-08-27 DK DK198704472A patent/DK173186B1/da not_active IP Right Cessation
- 1987-08-27 FI FI873729A patent/FI96620C/fi not_active IP Right Cessation
- 1987-08-28 IE IE230887A patent/IE59986B1/en not_active IP Right Cessation
- 1987-08-28 GB GB8720396A patent/GB2196635B/en not_active Expired - Lifetime
- 1987-08-28 AT AT87307668T patent/ATE87331T1/de not_active IP Right Cessation
- 1987-08-28 JP JP62214939A patent/JP2641457B2/ja not_active Expired - Lifetime
- 1987-08-28 AU AU77657/87A patent/AU604257B2/en not_active Expired
- 1987-08-28 ZA ZA876447A patent/ZA876447B/xx unknown
- 1987-08-28 DE DE8787307668T patent/DE3784986T2/de not_active Expired - Lifetime
- 1987-08-28 ES ES87307668T patent/ES2054682T3/es not_active Expired - Lifetime
- 1987-08-28 EP EP87307668A patent/EP0258067B1/en not_active Expired - Lifetime
- 1987-08-28 CA CA000545645A patent/CA1291428C/en not_active Expired - Lifetime
-
1993
- 1993-09-10 US US08/119,926 patent/US5739007A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA876447B (en) | 1988-05-25 |
| ATE87331T1 (de) | 1993-04-15 |
| DK447287A (da) | 1988-05-20 |
| DE3784986T2 (de) | 1993-07-01 |
| FI873729L (fi) | 1988-03-01 |
| US5739007A (en) | 1998-04-14 |
| FI96620C (fi) | 1996-07-25 |
| FI873729A0 (fi) | 1987-08-27 |
| JP2641457B2 (ja) | 1997-08-13 |
| AU7765787A (en) | 1988-05-19 |
| GB2196635A (en) | 1988-05-05 |
| DK173186B1 (da) | 2000-03-06 |
| JPS63112988A (ja) | 1988-05-18 |
| IE59986B1 (en) | 1994-05-04 |
| EP0258067A2 (en) | 1988-03-02 |
| AU604257B2 (en) | 1990-12-13 |
| GB2196635B (en) | 1990-12-05 |
| GB8620926D0 (en) | 1986-10-08 |
| FI96620B (fi) | 1996-04-15 |
| CA1291428C (en) | 1991-10-29 |
| GB8720396D0 (en) | 1987-10-07 |
| EP0258067A3 (en) | 1989-05-10 |
| EP0258067B1 (en) | 1993-03-24 |
| DE3784986D1 (en) | 1993-04-29 |
| ES2054682T3 (es) | 1994-08-16 |
| IE872308L (en) | 1988-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |