DK448981A - Fremgangsmaade til fremstilling af 4-chinolinmethanderivater - Google Patents

Fremgangsmaade til fremstilling af 4-chinolinmethanderivater

Info

Publication number
DK448981A
DK448981A DK448981A DK448981A DK448981A DK 448981 A DK448981 A DK 448981A DK 448981 A DK448981 A DK 448981A DK 448981 A DK448981 A DK 448981A DK 448981 A DK448981 A DK 448981A
Authority
DK
Denmark
Prior art keywords
methether
chinoline
derivatives
procedure
preparation
Prior art date
Application number
DK448981A
Other languages
English (en)
Other versions
DK169435B1 (da
Inventor
E Hickmann
H G Oeser
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of DK448981A publication Critical patent/DK448981A/da
Application granted granted Critical
Publication of DK169435B1 publication Critical patent/DK169435B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK448981A 1980-10-11 1981-10-09 2-Pyridyl-4-chinolylmethanderivater og fremgangsmåde til fremstilling af 2-pyridyl-4-chinolylketoner DK169435B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3038504 1980-10-11
DE19803038504 DE3038504A1 (de) 1980-10-11 1980-10-11 Neue 4-chinolinmethanderivate, ihre herstellung und verwendung zur darstellung von substanzen mit arzneimittelwirkung

Publications (2)

Publication Number Publication Date
DK448981A true DK448981A (da) 1982-04-12
DK169435B1 DK169435B1 (da) 1994-10-31

Family

ID=6114192

Family Applications (1)

Application Number Title Priority Date Filing Date
DK448981A DK169435B1 (da) 1980-10-11 1981-10-09 2-Pyridyl-4-chinolylmethanderivater og fremgangsmåde til fremstilling af 2-pyridyl-4-chinolylketoner

Country Status (7)

Country Link
US (1) US4429130A (da)
EP (1) EP0049776B1 (da)
JP (1) JPS5793961A (da)
DE (2) DE3038504A1 (da)
DK (1) DK169435B1 (da)
GR (1) GR74977B (da)
HU (1) HU183612B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191508B (en) * 1982-12-02 1987-02-27 Alkaloida Vegyeszeti Gyar,Hu Process for preparing new chloromethyl-quinoline derivatives
HU188235B (en) * 1982-12-11 1986-03-28 Alkaloida Vegyeszeti Gyar,Hu Process for producing fluoro-methyl-quinoline derivatives
DE3482926D1 (de) * 1983-10-07 1990-09-13 Hoffmann La Roche Mefloquin-hydrochlorid.
CH667267A5 (de) * 1986-05-26 1988-09-30 Mepha Ag Verfahren zur herstellung von (2,8-bis-(trifluormethyl)-4-chinolyl)-2-pyridinyl-methanon.
HUT54363A (en) * 1989-07-25 1991-02-28 Alkaloida Vegyeszeti Gyar Process for producing pyridyl-methyl-quinolin derivatives
GB9819382D0 (en) * 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I
US6500955B1 (en) 2001-02-02 2002-12-31 National Institute Of Pharmaceutical Education And Research One pot synthesis of [2,8-Bis (trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone, a mefloquine intermediate
DE112016007146B4 (de) 2016-09-20 2019-12-24 Mitsubishi Electric Corporation Störungsidentifizierungsvorrichtung und Störungsidentifizierungsverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2568778A (en) 1948-05-28 1951-09-25 Sterling Drug Inc Tertiary-aminoalkyl-alpha-arylalpha-(4-quinolyl) acetates and amides and their preparation
US2570286A (en) 1948-05-28 1951-10-09 Sterling Drug Inc Tertiary-amino-2-aryl-2-(4-quinolyl) alkane-nitriles and their preparation
FR2381044A1 (fr) 1977-02-17 1978-09-15 Hoffmann La Roche Procede pour la preparation de mefloquine

Also Published As

Publication number Publication date
GR74977B (da) 1984-07-12
EP0049776A2 (de) 1982-04-21
DK169435B1 (da) 1994-10-31
EP0049776A3 (en) 1982-05-19
JPH0261473B2 (da) 1990-12-20
JPS5793961A (en) 1982-06-11
DE3038504A1 (de) 1982-06-03
DE3171591D1 (en) 1985-09-05
HU183612B (en) 1984-05-28
US4429130A (en) 1984-01-31
EP0049776B1 (de) 1985-07-31

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired