DK453285A - Syntetisk signalsekvens og dens anvendelse, bl.a. til transportekspressioner af proteiner - Google Patents

Syntetisk signalsekvens og dens anvendelse, bl.a. til transportekspressioner af proteiner Download PDF

Info

Publication number: DK453285A
Authority: DK; Denmark
Prior art keywords: transport; signal sequence; expressions; proteins; application
Prior art date: 1984-10-06

Application number

DK453285A

Other languages

English (en)

Other versions

DK453285D0 (da

DK175511B1 (da

Inventor

Joachim Engels

Michael Leineweber

Eugen Uhlmann

Waldemar Wetekam

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-06

Filing date

1985-10-04

Publication date

1986-04-07

1985-10-04 Application filed by Hoechst Ag filed Critical Hoechst Ag

1985-10-04 Publication of DK453285D0 publication Critical patent/DK453285D0/da

1986-04-07 Publication of DK453285A publication Critical patent/DK453285A/da

2004-11-15 Application granted granted Critical

2004-11-15 Publication of DK175511B1 publication Critical patent/DK175511B1/da

Links

108010076504 Protein Sorting Signals Proteins 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
238000010348 incorporation Methods 0.000 abstract 2
239000013598 vector Substances 0.000 abstract 2
102000004533 Endonucleases Human genes 0.000 abstract 1
108010042407 Endonucleases Proteins 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
210000000805 cytoplasm Anatomy 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Plant Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

DK198504532A 1984-10-06 1985-10-04 DNA-sekvens, fremgangsmåde til transportekspression af proteiner ved anvendelse af DNA-sekvensen, hybridvektor og hybridplasmid indeholdende DNA-sekvensen samt værtsorganisme indeholdende hybridvektoren eller hybridplasmidet DK175511B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3436818		1984-10-06
DE19843436818 DE3436818A1 (de)	1984-10-06	1984-10-06	Synthetische signalsequenz zum transport von proteinen in expressionssystemen

Publications (3)

Publication Number	Publication Date
DK453285D0 DK453285D0 (da)	1985-10-04
DK453285A true DK453285A (da)	1986-04-07
DK175511B1 DK175511B1 (da)	2004-11-15

Family

ID=6247347

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198504532A DK175511B1 (da)	1984-10-06	1985-10-04	DNA-sekvens, fremgangsmåde til transportekspression af proteiner ved anvendelse af DNA-sekvensen, hybridvektor og hybridplasmid indeholdende DNA-sekvensen samt værtsorganisme indeholdende hybridvektoren eller hybridplasmidet

Country Status (15)

Country	Link
EP (1)	EP0177827B1 (da)
JP (1)	JPS6188883A (da)
AT (1)	ATE97445T1 (da)
AU (1)	AU595486B2 (da)
CA (1)	CA1340280C (da)
DE (2)	DE3436818A1 (da)
DK (1)	DK175511B1 (da)
ES (1)	ES8605579A1 (da)
GR (1)	GR852405B (da)
HU (1)	HU197355B (da)
IE (1)	IE63262B1 (da)
IL (1)	IL76573A (da)
NZ (1)	NZ213717A (da)
PH (1)	PH30819A (da)
PT (1)	PT81253B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0196864A3 (en) *	1985-03-25	1988-03-23	Cetus Corporation	Alkaline phosphatase-mediated processing and secretion of recombinant proteins, dna sequences for use therein and cells transformed using such sequences
IT1196484B (it) *	1986-07-11	1988-11-16	Sclavo Spa	Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
US5426036A (en) *	1987-05-05	1995-06-20	Hoechst Aktiengesellschaft	Processes for the preparation of foreign proteins in streptomycetes
DE68917759T2 (de) *	1988-03-18	1995-04-27	Wang Laboratories	Verteilte Referenz- und Änderungstabelle für ein virtuelles Speichersystem.
US20070020630A1 (en)	2003-03-27	2007-01-25	Trotta Christopher R	Methods of identifying compounds that target trna splicing endonuclease and uses of said compounds as anti-proliferative agents
WO2004087070A2 (en)	2003-03-27	2004-10-14	Ptc Therapeutics, Inc.	METHODS OF IDENTIFYING COMPOUNDS THAT TARGET tRNA SPLICING ENDONUCLEASE AND USES OF SAID COMPOUNDS AS ANTI-FUNGAL AGENTS
JP4990621B2 (ja)	2003-07-02	2012-08-01	ピーティーシーセラピューティクス，インコーポレーテッド	Ｒｎａプロセシングタンパク質複合体及びその使用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5939899A (ja) *	1982-08-27	1984-03-05	Gakuzo Tamura	新規ベクタ−
US4711844A (en) *	1983-03-09	1987-12-08	Cetus Corporation	Modified signal peptides
NZ207925A (en) *	1983-04-25	1988-05-30	Genentech Inc	Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture
US4663280A (en) *	1983-05-19	1987-05-05	Public Health Research Institute Of The City Of New York	Expression and secretion vectors and method of constructing vectors
AU3011684A (en) *	1983-05-19	1984-12-04	Public Health Research Institute Of The City Of New York, Inc., The	Expression and secretion vectors & method of constructing vectors
JPS6030687A (ja) *	1983-08-01	1985-02-16	Wakunaga Seiyaku Kk	Ｄνａ遺伝子，その製造法およびそれを含むプラスミド
DE3587205T2 (de) *	1984-07-30	1993-08-26	Wakunaga Seiyaku Kk	Verfahren zur herstellung eines proteins und dafuer zu verwendender vektor, rekombinante dns und transformierte zelle.

1984
- 1984-10-06 DE DE19843436818 patent/DE3436818A1/de not_active Withdrawn
1985
- 1985-09-23 AT AT85112043T patent/ATE97445T1/de not_active IP Right Cessation
- 1985-09-23 DE DE85112043T patent/DE3587660D1/de not_active Expired - Lifetime
- 1985-09-23 EP EP85112043A patent/EP0177827B1/de not_active Expired - Lifetime
- 1985-09-30 HU HU853761A patent/HU197355B/hu unknown
- 1985-10-03 JP JP60221120A patent/JPS6188883A/ja active Pending
- 1985-10-04 AU AU48333/85A patent/AU595486B2/en not_active Expired
- 1985-10-04 IE IE244085A patent/IE63262B1/en not_active IP Right Cessation
- 1985-10-04 ES ES547600A patent/ES8605579A1/es not_active Expired
- 1985-10-04 DK DK198504532A patent/DK175511B1/da not_active IP Right Cessation
- 1985-10-04 IL IL76573A patent/IL76573A/xx not_active IP Right Cessation
- 1985-10-04 NZ NZ213717A patent/NZ213717A/xx unknown
- 1985-10-04 PT PT81253A patent/PT81253B/pt unknown
- 1985-10-04 CA CA000492345A patent/CA1340280C/en not_active Expired - Fee Related
- 1985-10-04 GR GR852405A patent/GR852405B/el unknown
- 1985-10-14 PH PH32879A patent/PH30819A/en unknown

Also Published As

Publication number	Publication date
DE3587660D1 (de)	1993-12-23
IE852440L (en)	1986-04-06
EP0177827B1 (de)	1993-11-18
AU4833385A (en)	1986-04-10
DE3436818A1 (de)	1986-04-10
ATE97445T1 (de)	1993-12-15
JPS6188883A (ja)	1986-05-07
EP0177827A2 (de)	1986-04-16
CA1340280C (en)	1998-12-22
ES547600A0 (es)	1986-03-16
IL76573A (en)	1992-06-21
HU197355B (en)	1989-03-28
HUT40164A (en)	1986-11-28
EP0177827A3 (en)	1987-12-02
DK453285D0 (da)	1985-10-04
NZ213717A (en)	1989-01-06
AU595486B2 (en)	1990-04-05
IE63262B1 (en)	1995-04-05
PH30819A (en)	1997-10-17
DK175511B1 (da)	2004-11-15
GR852405B (da)	1986-02-04
ES8605579A1 (es)	1986-03-16
PT81253B (pt)	1987-11-30
PT81253A (de)	1985-11-01
IL76573A0 (en)	1986-02-28

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Legal Events

Date	Code	Title	Description
2005-10-24	PUP	Patent expired