IT1196484B - Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe - Google Patents

Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Info

Publication number
IT1196484B
IT1196484B IT21106/86A IT2110686A IT1196484B IT 1196484 B IT1196484 B IT 1196484B IT 21106/86 A IT21106/86 A IT 21106/86A IT 2110686 A IT2110686 A IT 2110686A IT 1196484 B IT1196484 B IT 1196484B
Authority
IT
Italy
Prior art keywords
useful
preparation
yeast expression
secretion vector
heterological
Prior art date
Application number
IT21106/86A
Other languages
English (en)
Other versions
IT8621106A0 (it
IT8621106A1 (it
Inventor
Cesira Galeotti
Emanuela Palla
Giovanni Raugei
Giuliano Bensi
Maria Luisa Melli
Original Assignee
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo Spa filed Critical Sclavo Spa
Priority to IT21106/86A priority Critical patent/IT1196484B/it
Publication of IT8621106A0 publication Critical patent/IT8621106A0/it
Priority to EP87201264A priority patent/EP0252561A3/en
Priority to JP62171295A priority patent/JPS6387983A/ja
Priority to CA000541825A priority patent/CA1324967C/en
Publication of IT8621106A1 publication Critical patent/IT8621106A1/it
Application granted granted Critical
Publication of IT1196484B publication Critical patent/IT1196484B/it
Priority to US08/069,455 priority patent/US5432082A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT21106/86A 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe IT1196484B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
EP87201264A EP0252561A3 (en) 1986-07-11 1987-07-03 Expression and secretion vector in yeasts, useful for preparing heterologous proteins
JP62171295A JPS6387983A (ja) 1986-07-11 1987-07-10 酵母の発現及び分泌クロ−ニングベクタ−
CA000541825A CA1324967C (en) 1986-07-11 1987-07-10 Expression and secretion vector in yeasts, useful for preparing heterologous proteins
US08/069,455 US5432082A (en) 1986-07-11 1993-06-01 Expression and secretion vector in yeasts, useful for preparing heterologous proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Publications (3)

Publication Number Publication Date
IT8621106A0 IT8621106A0 (it) 1986-07-11
IT8621106A1 IT8621106A1 (it) 1988-01-11
IT1196484B true IT1196484B (it) 1988-11-16

Family

ID=11176829

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Country Status (5)

Country Link
US (1) US5432082A (it)
EP (1) EP0252561A3 (it)
JP (1) JPS6387983A (it)
CA (1) CA1324967C (it)
IT (1) IT1196484B (it)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633020B2 (en) * 1988-07-23 1993-01-21 Novozymes Delta Limited New secretory leader sequences
FR2636231A1 (fr) * 1988-09-09 1990-03-16 Sanofi Sa Cellules eucaryotes recombinees productrices d'interleukine-1 (beta) mature n-glycosylee, procede et vecteurs necessaires pour leur obtention et procede d'obtention d'interleukine-1 (beta) mature n-glycosylee
IT1231156B (it) * 1989-07-19 1991-11-19 Eniricerche Spa Espressione e secrezione di interleuchina 1 beta umana matura in bacillus subtilis e mezzi e metodi per il suo ottenimento.
IT1251435B (it) * 1991-09-04 1995-05-09 Sclavo Spa Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono.
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP0662515B1 (en) * 1993-12-10 2000-11-15 Korea Institute Of Science And Technology Signal sequences for secretion of heterologous proteins from yeast
RU2143113C1 (ru) * 1996-08-01 1999-12-20 Андрей Александрович Елов Способ диагностики инфекций путем обнаружения генетического материала возбудителя в исследуемой пробе
CA2283789C (en) 1997-03-12 2005-07-05 Applied Biosystems, Llc Dna polymerases having improved labeled nucleotide incorporation properties
WO1999013093A1 (en) * 1997-09-05 1999-03-18 Pentapharm Ag Expression vector for improved production of polypeptides in yeast
EP1274720A4 (en) 2000-04-12 2004-08-18 Human Genome Sciences Inc FUSION PROTEINS CONTAINING ALBUMIN
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
US20050042629A1 (en) 2002-09-13 2005-02-24 Applera Corporation Thermus scotoductus nucleic acid polymerases
AU2002346498A1 (en) 2001-11-30 2003-06-17 Applera Corporation Thermus brockianus nucleic acid polymerases
PT1463751E (pt) 2001-12-21 2013-08-26 Human Genome Sciences Inc Proteínas de fusão de albumina
EP1463752A4 (en) 2001-12-21 2005-07-13 Human Genome Sciences Inc ALBUM INFUSION PROTEINS
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
DE10342794A1 (de) * 2003-09-16 2005-04-21 Basf Ag Sekretion von Proteinen aus Hefen
US7892788B2 (en) 2005-02-07 2011-02-22 Basf Se Hydrophobin fusion products, production and use thereof
BRPI0607594A2 (pt) 2005-03-31 2010-04-06 Basf Ag compósito multi-camadas ou substrato revestido, processo para a preparação dos mesmos, e, uso de hidrofobinas
MX2007011955A (es) 2005-04-01 2007-12-05 Basf Ag Uso de hidrofobina como estabilizador de fases.
MX270311B (es) 2005-04-01 2009-09-23 Basf Ag Fluido de perforacion que comprende hidrofobina.
DE102005027139A1 (de) 2005-06-10 2006-12-28 Basf Ag Neue Cystein-verarmte Hydrophobinfusionsproteine, deren Herstellung und Verwendung
JP4769804B2 (ja) 2005-07-25 2011-09-07 富士通株式会社 受音装置
DE102005048720A1 (de) 2005-10-12 2007-04-19 Basf Ag Verwendung von Proteinen als Antischaum-Komponente in Kraftstoffen
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
CN101501432B (zh) 2006-08-15 2011-10-12 巴斯夫欧洲公司 制备干燥的自由流动的疏水蛋白制剂的方法
JPWO2008029514A1 (ja) * 2006-09-07 2010-01-21 株式会社テムコジャパン 振動ピックアップマイクロホン
US20140017263A1 (en) 2012-06-28 2014-01-16 Clemson University Delivery Agents for Targeted Treatment of Elastin Degradation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004330A1 (en) * 1983-04-22 1984-11-08 Amgen Secretion of exogenous polypeptides from yeast
DE3436818A1 (de) * 1984-10-06 1986-04-10 Hoechst Ag, 6230 Frankfurt Synthetische signalsequenz zum transport von proteinen in expressionssystemen

Also Published As

Publication number Publication date
IT8621106A0 (it) 1986-07-11
CA1324967C (en) 1993-12-07
JPS6387983A (ja) 1988-04-19
IT8621106A1 (it) 1988-01-11
US5432082A (en) 1995-07-11
EP0252561A2 (en) 1988-01-13
EP0252561A3 (en) 1989-03-29

Similar Documents

Publication Publication Date Title
IT8621106A1 (it) Vettore ad espressione e secrezione in lieviti, utile per la preparazione di proteine eterologhe
IT1232827B (it) Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle
FI881736L (fi) Olutmäskiuutteen käyttö kosmeettisten valmisteiden valmistukseen, kosmeettinen valmiste ja olutmäskiuute
DE3485267D1 (de) Herstellung von streptokokken-m-protein-immunogenen und molekularen sonden.
FI872470A7 (fi) Galaktoosin säätelemän geeniekspression indusointi hiivassa.
FI924746A7 (fi) Kohydrolyysimenetelmä uusien uutteiden valmistamiseksi hiiva- ja ei-hi ivaproteiineista
EP0240550A4 (en) TENSIO-ACTIVE PULMONARY PROTEINS.
KR890700661A (ko) 효모에 의한 플라즈모듐 팔시파룸의 외주포자소체 단백질의 발현
IT8821300A0 (it) Procedimento di preparazione di morniflumato e analoghi.
IT1198225B (it) Polipeptidi immunologicamente attivi utili per la preparazione di vaccini antimalaria e di kits diagnostici per la determinazione di anticorpi antisporozoita
AU585422B2 (en) Production of human serum albumin in bacillus
NO891687D0 (no) Ekspresjon av hepatitt-b pres2-protein i metylotrofe gjaersorter.
IT8620863A0 (it) Fibra cava di poliestere ammide eprocedimento per la sua preparazione.
NO881942D0 (no) Fremgangsmaate for fremstilling av fremmede proteiner i streptomyceten.
IT1187655B (it) Procedimento per la preparazione di w-lattami,in particolare caprolattame
IT1238207B (it) Preparato vitaminizzato contenente l'enzima lisozima impiegabile in zootecnica e procedimento per la sua produzione.
IT8722055A0 (it) Procedimento per la preparazione di idantoine 5-ariliden e alchilidensostituite.
IT1228559B (it) Procedimento per la preparazione di enzima mieloperossidasi.
IT8621144A0 (it) Polipeptide utile per lapreparazione di vaccini per la malaria e di kits diagnostici per la determinazione di affezioni malariche.
DE3672591D1 (de) Enzymimmunoassaymethode fuer den hautwachstumsfaktor.
DK511687D0 (da) Farmaceutisk praeparat, samt fremstilling og anvendelse heraf
FI874602A7 (fi) Uudet hiivaekspressiovektorit omega-interferoneille, niiden valmistusmenetelmä ja niiden käyttö.
IT1200177B (it) Procedimento per la fabbricazione di protesi di capelli
IT1172306B (it) Procedimento per la produzione e la immobilizzazione di proteine modificate
IT1215534B (it) Procedimento per la realizzazione di giunti impermeabili in diaframmi e diaframma relativo.