DK460181A - Fremgangsmaade til fremstilling af azebicyclooctancar boxylsyrer - Google Patents

Fremgangsmaade til fremstilling af azebicyclooctancar boxylsyrer

Info

Publication number
DK460181A
DK460181A DK460181A DK460181A DK460181A DK 460181 A DK460181 A DK 460181A DK 460181 A DK460181 A DK 460181A DK 460181 A DK460181 A DK 460181A DK 460181 A DK460181 A DK 460181A
Authority
DK
Denmark
Prior art keywords
azebicyclooctancar
procedure
preparation
boxyl
acid
Prior art date
Application number
DK460181A
Other languages
English (en)
Other versions
DK162444B (da
DK162444C (da
Inventor
M Vincent
G Remond
M Laubie
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Publication of DK460181A publication Critical patent/DK460181A/da
Publication of DK162444B publication Critical patent/DK162444B/da
Application granted granted Critical
Publication of DK162444C publication Critical patent/DK162444C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK460181A 1980-10-21 1981-10-19 Analogifremgangsmaade til fremstilling af azabicyklooctancarboxylsyrer og farmaceutisk acceptable salte heraf DK162444C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8022438A FR2492381A1 (fr) 1980-10-21 1980-10-21 Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR8022438 1980-10-21

Publications (3)

Publication Number Publication Date
DK460181A true DK460181A (da) 1982-04-22
DK162444B DK162444B (da) 1991-10-28
DK162444C DK162444C (da) 1992-03-23

Family

ID=9247120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK460181A DK162444C (da) 1980-10-21 1981-10-19 Analogifremgangsmaade til fremstilling af azabicyklooctancarboxylsyrer og farmaceutisk acceptable salte heraf

Country Status (29)

Country Link
US (1) US4397857A (da)
EP (1) EP0051020B1 (da)
JP (2) JPS5798281A (da)
KR (1) KR860001877B1 (da)
AR (1) AR228621A1 (da)
AT (1) ATE8892T1 (da)
AU (1) AU540609B2 (da)
CA (1) CA1183140A (da)
DD (1) DD201891A5 (da)
DE (1) DE3165428D1 (da)
DK (1) DK162444C (da)
EG (1) EG15419A (da)
ES (1) ES8301927A1 (da)
FI (1) FI73678C (da)
FR (2) FR2492381A1 (da)
GR (1) GR75389B (da)
HU (1) HU185058B (da)
IE (1) IE51823B1 (da)
IL (1) IL64075A0 (da)
MA (1) MA19307A1 (da)
MX (1) MX155032A (da)
NO (1) NO155098C (da)
NZ (1) NZ198701A (da)
OA (1) OA06930A (da)
PH (1) PH17338A (da)
PT (1) PT73857B (da)
SU (1) SU1138022A3 (da)
YU (1) YU42587B (da)
ZA (1) ZA817251B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU88621I2 (fr) * 1980-10-23 1995-09-01 Schering Corp Sandopril
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
DE3246757A1 (de) * 1982-12-17 1984-06-20 Hoechst Ag, 6230 Frankfurt Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US4693996A (en) * 1985-12-23 1987-09-15 Warner-Lambert Company Method of treating heart failure and medicaments therefor
DE3707911C1 (de) * 1987-03-12 1988-03-31 Texaco Ag Bicyclische Aminkatalysatoren
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
JPH0426348U (da) * 1990-06-25 1992-03-02
TW197945B (da) * 1990-11-27 1993-01-11 Hoechst Ag
LT3872B (en) 1993-12-06 1996-04-25 Hoechst Ag Novel peptides and pharmaceutical compositions containing them
ES2171768T3 (es) 1996-03-20 2002-09-16 Hoechst Ag Inhibidores de la resorcion osea y antagonistas de receptores de vitronectina.
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7001911B2 (en) * 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
MXPA02012605A (es) 2000-06-28 2003-05-14 Squibb Bristol Myers Co Moduladores selectivos del receptor androgeno y metodo para su identificacion, dise°o y uso.
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7087636B2 (en) * 2001-12-19 2006-08-08 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE94175C (da) *
GB1095105A (en) * 1965-04-12 1967-12-13 Scherico Ltd Novel n-(phenyl-sulfonyl)-isoquinuclidine-carboxamides
US3740408A (en) * 1967-09-11 1973-06-19 Upjohn Co Oxygenated 3-aza bicyclo(3,3,1)nonanes
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

Also Published As

Publication number Publication date
ES506222A0 (es) 1983-01-01
AU540609B2 (en) 1984-11-29
JPS6146453B2 (da) 1986-10-14
FR2525604B2 (fr) 1985-06-07
JPS5798281A (en) 1982-06-18
AR228621A1 (es) 1983-03-30
PT73857B (fr) 1983-01-25
JPS61126025A (ja) 1986-06-13
OA06930A (fr) 1983-05-31
FI73678B (fi) 1987-07-31
PH17338A (en) 1984-08-01
FI813279L (fi) 1982-04-22
NO155098B (no) 1986-11-03
IE51823B1 (en) 1987-04-01
FR2492381A1 (fr) 1982-04-23
YU42587B (en) 1988-10-31
JPS6112911B2 (da) 1986-04-10
DD201891A5 (de) 1983-08-17
MA19307A1 (fr) 1982-07-01
DE3165428D1 (en) 1984-09-13
FR2492381B1 (da) 1983-08-12
IL64075A0 (en) 1982-01-31
ES8301927A1 (es) 1983-01-01
EP0051020A1 (fr) 1982-05-05
GR75389B (da) 1984-07-13
KR860001877B1 (ko) 1986-10-24
AU7662481A (en) 1982-04-29
US4397857A (en) 1983-08-09
YU245481A (en) 1984-04-30
NO155098C (no) 1987-02-11
PT73857A (fr) 1981-11-01
ATE8892T1 (de) 1984-08-15
IE812460L (en) 1982-04-21
SU1138022A3 (ru) 1985-01-30
HU185058B (en) 1984-11-28
NZ198701A (en) 1984-07-06
KR830007570A (ko) 1983-10-21
FI73678C (fi) 1987-11-09
EG15419A (en) 1986-03-31
DK162444B (da) 1991-10-28
CA1183140A (fr) 1985-02-26
ZA817251B (en) 1982-09-29
EP0051020B1 (fr) 1984-08-08
MX155032A (es) 1988-01-21
FR2525604A2 (fr) 1983-10-28
NO813541L (no) 1982-04-22
DK162444C (da) 1992-03-23

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