DK462376A - Fremgangsmade til fremstilling af 5-halogenpyrimidinderivater - Google Patents

Fremgangsmade til fremstilling af 5-halogenpyrimidinderivater

Info

Publication number: DK462376A
Authority: DK; Denmark
Prior art keywords: halogenpyrimidine; derivatives; preparing; procedure; halogenpyrimidine derivatives
Prior art date: 1975-10-16

Application number

DK462376A

Other languages

English (en)

Other versions

DK144525C (da

DK144525B (da

Inventor

K Undheim

S G M Laland

M J Gacek

R Oftebro

Original Assignee

Nyegaard & Co As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-16

Filing date

1976-10-14

Publication date

1977-04-17

1976-10-14 Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As

1977-04-17 Publication of DK462376A publication Critical patent/DK462376A/da

1982-03-22 Publication of DK144525B publication Critical patent/DK144525B/da

1982-10-18 Application granted granted Critical

1982-10-18 Publication of DK144525C publication Critical patent/DK144525C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

DK462376A 1975-10-16 1976-10-14 Analogifremgangsmaade til fremstilling af 5-halogenpyrimid-2-oner eller salte deraf DK144525C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB4250975		1975-10-16
GB42509/75A GB1561290A (en)	1975-10-16	1975-10-16	Pyrimid - 2 - ones

Publications (3)

Publication Number	Publication Date
DK462376A true DK462376A (da)	1977-04-17
DK144525B DK144525B (da)	1982-03-22
DK144525C DK144525C (da)	1982-10-18

Family

ID=10424751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK462376A DK144525C (da)	1975-10-16	1976-10-14	Analogifremgangsmaade til fremstilling af 5-halogenpyrimid-2-oner eller salte deraf

Country Status (14)

Country	Link
US (1)	US4395406A (da)
JP (1)	JPS5253869A (da)
BE (1)	BE847234A (da)
CA (1)	CA1086736A (da)
CH (3)	CH634308A5 (da)
DE (1)	DE2646676A1 (da)
DK (1)	DK144525C (da)
FR (1)	FR2327765A1 (da)
GB (1)	GB1561290A (da)
IE (1)	IE44431B1 (da)
LU (1)	LU75994A1 (da)
NL (1)	NL7611415A (da)
NO (1)	NO151040C (da)
SE (1)	SE439305B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1582884A (en) *	1977-05-19	1981-01-14	Beecham Group Ltd	Clavulanic acid derivatives their preparation and use
ZA804670B (en) *	1979-08-03	1981-07-29	Beecham Group Ltd	Derivatives of clavulanic acid, a process for their preparation and their use
ES498337A0 (es) *	1980-01-07	1982-06-01	Nyegaard & Co As	Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
AU549117B2 (en)	1980-01-10	1986-01-16	Nyegaard & Co. A/S	Pyrimidine-2-sulphides and their 5-oxides
CA1160226A (en) *	1980-07-15	1984-01-10	Gordon H. Phillipps	Substituted pyrimidin-2-ones, the salts thereof, processes for their preparation, pharmaceutical compositions containing them and a method therefor
NZ197715A (en) *	1980-07-15	1984-12-14	Glaxo Group Ltd	Substituted pyrimin-2-ones and pharmaceutical compositions
NZ199061A (en) *	1980-12-09	1984-10-19	Beecham Group Ltd	9-(n-tetrazolyl)-deoxyclavulanic acids,salts,esters,and pharmaceutical compositions
NZ199200A (en) *	1980-12-23	1984-07-31	Beecham Group Ltd	Clavulanic acid derivatives and pharmaceutical compositions
US4596870A (en) *	1981-01-09	1986-06-24	Nyegaard & Co. A.S.	Substituted pyrimidin-2-ones and the salts thereof
ZA826660B (en) *	1981-09-11	1983-08-31	Nyegaard & Co As	Substituted pyrimid-2-ones,the salts thereof,processes for their preparation and pharmaceutical compositions containing them
US4782142A (en) *	1982-01-05	1988-11-01	The Research Foundation Of State University Of New York	Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
EP0087326B1 (en) *	1982-02-24	1987-05-13	Nycomed As	Substituted pyrimidin-2-ones and the salts thereof
CA1275410C (en) *	1986-03-14	1990-10-23	Karnail S. Atwal	1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo) -3-substituted-2-thioxo(or oxo)-5- pyrimidinecarboxylic acids and esters
GB8706176D0 (en) *	1987-03-16	1987-04-23	Wellcome Found	Therapeutic nucleosides
DE68920880D1 (de) *	1988-07-18	1995-03-09	Yamasa Shoyu Kk	1-amino-5-halogenouracile, verfahren zu deren herstellung und diese enthaltende cns-depressiva.
GB9026114D0 (en) *	1990-11-30	1991-01-16	Norsk Hydro As	New compounds
AU7286696A (en) *	1995-10-13	1997-05-07	F. Hoffmann-La Roche Ag	Antisense oligomers
NZ330360A (en) *	1997-06-02	1999-03-29	Hoffmann La Roche	5'-deoxy-cytidine derivatives, their manufacture and use as antitumoral agents
EP0882734B1 (en) *	1997-06-02	2009-08-26	F. Hoffmann-La Roche Ag	5'-Deoxy-cytidine derivatives
US6005098A (en) *	1998-02-06	1999-12-21	Hoffmann-La Roche Inc.	5'deoxycytidine derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3317532A (en) *	1964-11-19	1967-05-02	Hoffmann La Roche	Derivatives of pyrimidine
DE2032559A1 (de) *	1970-06-27	1972-01-13	Schering Ag Berlin Und Bergkamen, 1000 Berlin	N-Substituierte Amide und Lactame
US3833586A (en) *	1971-03-25	1974-09-03	Morton Norwich Products Inc	1-(substituted benzyl)-2-(1h)pyrimidones and 1-(substituted benzyl)tetrahydro-2-(1h)pyrimidones
DE2440677A1 (de) *	1974-08-24	1976-03-04	Bayer Ag	Pyrimidinylthionophosphonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
DE2450951A1 (de) *	1974-10-26	1976-05-06	Bayer Ag	Pyrimidinyl(thiono)(thiol)phosphor (phosphon)-saeureester bzw. -esteramide, verfahren zu ihrer herstellung und ihre verwendung als insektizide, akarizide und nematizide
US4003900A (en) *	1976-03-11	1977-01-18	Morton-Norwich Products, Inc.	1-Benzyl-5-chloro-2-(1H)-pyrimidone

1975
- 1975-10-16 GB GB42509/75A patent/GB1561290A/en not_active Expired
1976
- 1976-10-13 BE BE171474A patent/BE847234A/xx not_active IP Right Cessation
- 1976-10-14 LU LU75994A patent/LU75994A1/xx unknown
- 1976-10-14 FR FR7630923A patent/FR2327765A1/fr active Granted
- 1976-10-14 DK DK462376A patent/DK144525C/da not_active IP Right Cessation
- 1976-10-15 CA CA263,452A patent/CA1086736A/en not_active Expired
- 1976-10-15 DE DE19762646676 patent/DE2646676A1/de active Granted
- 1976-10-15 NO NO763533A patent/NO151040C/no unknown
- 1976-10-15 IE IE2284/76A patent/IE44431B1/en unknown
- 1976-10-15 CH CH1310376A patent/CH634308A5/de not_active IP Right Cessation
- 1976-10-15 SE SE7611493A patent/SE439305B/xx not_active IP Right Cessation
- 1976-10-15 NL NL7611415A patent/NL7611415A/xx not_active Application Discontinuation
- 1976-10-15 JP JP51123013A patent/JPS5253869A/ja active Pending
1980
- 1980-07-07 US US06/166,600 patent/US4395406A/en not_active Expired - Lifetime
1981
- 1981-06-18 CH CH405481A patent/CH634309A5/de not_active IP Right Cessation
- 1981-06-18 CH CH405581A patent/CH634310A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE44431B1 (en)	1981-12-02
DE2646676A1 (de)	1977-04-28
JPS5253869A (en)	1977-04-30
GB1561290A (en)	1980-02-20
FR2327765A1 (fr)	1977-05-13
NO151040B (no)	1984-10-22
NL7611415A (nl)	1977-04-19
CH634310A5 (de)	1983-01-31
BE847234A (fr)	1977-04-13
DE2646676C2 (da)	1987-06-19
DK144525C (da)	1982-10-18
CH634309A5 (de)	1983-01-31
LU75994A1 (da)	1977-05-11
DK144525B (da)	1982-03-22
FR2327765B1 (da)	1981-11-20
NO151040C (no)	1985-01-30
SE7611493L (sv)	1977-04-17
NO763533L (da)	1977-04-19
CH634308A5 (de)	1983-01-31
CA1086736A (en)	1980-09-30
IE44431L (en)	1977-04-16
SE439305B (sv)	1985-06-10
US4395406A (en)	1983-07-26

Legal Events

Date	Code	Title	Description
1988-07-04	PBP	Patent lapsed

Publication	Publication Date	Title
DK494876A (da)	1977-05-08	Fremgangsmade til fremstilling af piperidinderivater
DK298176A (da)	1977-01-03	Fremgangsmade til fremstilling af 1,4-dihydropyrinderivater
DK365176A (da)	1977-02-14	Fremgangsmade til fremstilling af pyrrolidinderivater
DK562376A (da)	1977-06-24	Fremgangsmade til fremstilling af ergolinderivater
DK518176A (da)	1977-05-19	Fremgangsmade til fremstilling af polyprenylderivater
DK145228C (da)	1983-02-28	Analogifremgangsmaade til fremstilling af 3-amino-4-deoxo-4-iminorifamycinderivater
DK155002C (da)	1989-06-12	Analogifremgangsmaade til fremstilling af salicylanilidderivater
DK243176A (da)	1976-12-04	Fremgangsmade til fremstilling af polycliske forbindelser
DK517776A (da)	1977-05-19	Fremgangsmade til femstilling af heterocycliske forbindelser
DK415676A (da)	1977-04-09	Fremgangsmade til fremstilling af pilocarpiniumsalte
DK29376A (da)	1976-07-28	Fremgangsmade til fremstilling af 1-aryloxy-3-n-substituerede aminopropanderivater
DK164476A (da)	1976-10-22	Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser
DK324776A (da)	1977-01-29	Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler
DK360576A (da)	1977-02-13	Fremgangsmade til fremstilling af pyridinderivater
DK117677A (da)	1977-09-19	Fremgangsmade til fremstilling af piperidinderivater
DK497976A (da)	1977-05-06	Fremgangsmade til fremstilling af alaninderivater
DK329577A (da)	1978-01-23	Fremgangsmade til fremstilling af derivater af phenoxyhydroxypropylamin
DK139267B (da)	1979-01-22	Fremgangsmaade til fremstilling af 4-androsten3,17-dionderivater
DK494976A (da)	1977-05-08	Fremgangsmade til fremstilling af purinderivater
DK305876A (da)	1977-01-09	Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid
DK97376A (da)	1976-09-09	Fremgangsmade til fremstilling af histidinderivater
DK155598C (da)	1989-09-25	Fremgangsmaade til fremstilling af ethylchlorthioformiat
DK143281C (da)	1981-12-07	Fremgangsmaade til fremstilling af phosphitchlorider
DK143137C (da)	1981-11-09	Fremgangsmaade til fremstilling af phosphitchlorider
DK365276A (da)	1977-02-14	Fremgangsmade til fremstilling af pyrrolinderivater