DK466886D0 - Estere af dihydrolysergsyre, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og praeparater indeholdende de aktive forbindelser - Google Patents
Estere af dihydrolysergsyre, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og praeparater indeholdende de aktive forbindelserInfo
- Publication number
- DK466886D0 DK466886D0 DK466886A DK466886A DK466886D0 DK 466886 D0 DK466886 D0 DK 466886D0 DK 466886 A DK466886 A DK 466886A DK 466886 A DK466886 A DK 466886A DK 466886 D0 DK466886 D0 DK 466886D0
- Authority
- DK
- Denmark
- Prior art keywords
- dihydrolyric
- esthers
- intermediates
- procedures
- preparing
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/782,341 US4713385A (en) | 1985-10-01 | 1985-10-01 | Alkoxy and dialkoxyalkyl esters of dihydrolysergic acid and related compounds useful as 5HT receptor antagonists |
| US06/782,340 US4714704A (en) | 1985-10-01 | 1985-10-01 | Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT receptor antagonists |
| US06/782,337 US4683236A (en) | 1985-10-01 | 1985-10-01 | Cycloalkanol esters of dihydrolysergic acid useful as 5Ht2 receptor antagonists |
| US06/782,338 US4713384A (en) | 1985-10-01 | 1985-10-01 | Selective method for blocking 5HT2 receptors |
| US06/782,342 US4772709A (en) | 1985-10-01 | 1985-10-01 | Process of making ketoalkanol esters of dihydrolysergic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK466886D0 true DK466886D0 (da) | 1986-09-30 |
| DK466886A DK466886A (da) | 1987-04-02 |
Family
ID=27542204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK466886A DK466886A (da) | 1985-10-01 | 1986-09-30 | Estere af dihydrolysergsyre, fremgangsmaade til fremstilling heraf, mellemprodukter til brug herved og praeparater indeholdende de aktive forbindelser |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0219257B1 (da) |
| JP (1) | JPH0723376B2 (da) |
| KR (1) | KR880001009B1 (da) |
| AR (1) | AR244687A1 (da) |
| AU (1) | AU594373B2 (da) |
| CY (1) | CY1784A (da) |
| DE (1) | DE3689702T2 (da) |
| DK (1) | DK466886A (da) |
| ES (1) | ES2002392A6 (da) |
| GR (1) | GR862466B (da) |
| HK (1) | HK51894A (da) |
| HU (1) | HU206711B (da) |
| IE (1) | IE61976B1 (da) |
| IL (1) | IL80193A0 (da) |
| MY (1) | MY102598A (da) |
| NZ (1) | NZ217724A (da) |
| PT (1) | PT83450B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4734501A (en) * | 1985-10-01 | 1988-03-29 | Eli Lilly And Company | N-alkylation of dihydrolysergic acid |
| US4782063A (en) * | 1987-05-11 | 1988-11-01 | Eli Lilly And Company | Ergoline esters useful as serotonin antagonists |
| GB8824744D0 (en) * | 1988-10-21 | 1988-11-30 | Erba Carlo Spa | Antiemesis ergoline derivatives |
| JPH11503757A (ja) * | 1995-04-18 | 1999-03-30 | イーライ・リリー・アンド・カンパニー | ５−ｈｔ▲下７▼レセプターにおいて生理学的および病理学的機能を生じるエルゴリン化合物の使用方法 |
| US5880134A (en) * | 1996-03-20 | 1999-03-09 | Eli Lilly And Company | Method for using ergoline compounds to effect physiological and pathological functions at the 5-HT7 receptor |
| RU2014149076A (ru) * | 2012-05-08 | 2016-06-27 | Мерк Патент Гмбх | Применение простых эфиров циклогексанола, обладающих антимикробными свойствами |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3580916A (en) * | 1969-02-20 | 1971-05-25 | Lilly Co Eli | Hydroxyesters of hexa- and octahydroindoloquinolines |
| CH549571A (de) * | 1970-09-16 | 1974-05-31 | Lilly Co Eli | Verfahren zur herstellung von estern der lysergsaeure bzw. dihydrolysergsaeure und deren verwendung. |
| US4563461A (en) * | 1983-03-10 | 1986-01-07 | Eli Lilly And Company | Selective method for blocking 5HT2 receptors |
| US4713384A (en) * | 1985-10-01 | 1987-12-15 | Eli Lilly And Company | Selective method for blocking 5HT2 receptors |
| US4734501A (en) * | 1985-10-01 | 1988-03-29 | Eli Lilly And Company | N-alkylation of dihydrolysergic acid |
-
1986
- 1986-09-29 EP EP86307443A patent/EP0219257B1/en not_active Expired - Lifetime
- 1986-09-29 IL IL80193A patent/IL80193A0/xx not_active IP Right Cessation
- 1986-09-29 DE DE3689702T patent/DE3689702T2/de not_active Expired - Fee Related
- 1986-09-29 AU AU63210/86A patent/AU594373B2/en not_active Ceased
- 1986-09-29 GR GR862466A patent/GR862466B/el unknown
- 1986-09-29 PT PT83450A patent/PT83450B/pt not_active IP Right Cessation
- 1986-09-29 NZ NZ217724A patent/NZ217724A/xx unknown
- 1986-09-30 ES ES8602320A patent/ES2002392A6/es not_active Expired
- 1986-09-30 JP JP61234256A patent/JPH0723376B2/ja not_active Expired - Lifetime
- 1986-09-30 HU HU864146A patent/HU206711B/hu not_active IP Right Cessation
- 1986-09-30 DK DK466886A patent/DK466886A/da not_active Application Discontinuation
- 1986-09-30 AR AR86305427A patent/AR244687A1/es active
- 1986-09-30 KR KR1019860008205A patent/KR880001009B1/ko not_active Expired
- 1986-09-30 IE IE258886A patent/IE61976B1/en not_active IP Right Cessation
-
1987
- 1987-09-24 MY MYPI87001918A patent/MY102598A/en unknown
-
1994
- 1994-05-19 HK HK51894A patent/HK51894A/xx unknown
-
1995
- 1995-10-20 CY CY178495A patent/CY1784A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY102598A (en) | 1992-08-17 |
| PT83450B (pt) | 1989-05-12 |
| DE3689702D1 (de) | 1994-04-14 |
| EP0219257B1 (en) | 1994-03-09 |
| HUT41780A (en) | 1987-05-28 |
| AR244687A1 (es) | 1993-11-30 |
| PT83450A (en) | 1986-10-01 |
| GR862466B (en) | 1987-02-02 |
| NZ217724A (en) | 1989-02-24 |
| KR870004028A (ko) | 1987-05-07 |
| AU6321086A (en) | 1987-04-02 |
| IE61976B1 (en) | 1994-12-14 |
| KR880001009B1 (ko) | 1988-06-13 |
| HK51894A (en) | 1994-05-27 |
| EP0219257A3 (en) | 1988-12-28 |
| DK466886A (da) | 1987-04-02 |
| JPH0723376B2 (ja) | 1995-03-15 |
| IL80193A0 (en) | 1986-12-31 |
| HU206711B (en) | 1992-12-28 |
| IE862588L (en) | 1987-04-01 |
| CY1784A (en) | 1995-10-20 |
| DE3689702T2 (de) | 1994-07-28 |
| ES2002392A6 (es) | 1988-08-01 |
| JPS6284084A (ja) | 1987-04-17 |
| EP0219257A2 (en) | 1987-04-22 |
| AU594373B2 (en) | 1990-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |