DK472788A - Substituerede 2-azabicyklooctan-3-carboxylsyrer, fremgangsmaade til deres fremstilling og farmaceutiske midler indholdende dem - Google Patents

Substituerede 2-azabicyklooctan-3-carboxylsyrer, fremgangsmaade til deres fremstilling og farmaceutiske midler indholdende dem

Info

Publication number
DK472788A
DK472788A DK472788A DK472788A DK472788A DK 472788 A DK472788 A DK 472788A DK 472788 A DK472788 A DK 472788A DK 472788 A DK472788 A DK 472788A DK 472788 A DK472788 A DK 472788A
Authority
DK
Denmark
Prior art keywords
formula
derivative
see diagramm
iii
compound
Prior art date
Application number
DK472788A
Other languages
English (en)
Other versions
DK170978B1 (da
DK472788D0 (da
Inventor
Michel Vincent
Georges Remond
Michel Laubie
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK472788D0 publication Critical patent/DK472788D0/da
Publication of DK472788A publication Critical patent/DK472788A/da
Application granted granted Critical
Publication of DK170978B1 publication Critical patent/DK170978B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK472788A 1987-08-28 1988-08-24 Derivater af 2-azabicyklo [2,2,2]octan-3-carboxylsyre, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende sådanne DK170978B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8712013 1987-08-28
FR8712013A FR2619813B1 (fr) 1987-08-28 1987-08-28 Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
DK472788D0 DK472788D0 (da) 1988-08-24
DK472788A true DK472788A (da) 1989-03-01
DK170978B1 DK170978B1 (da) 1996-04-09

Family

ID=9354475

Family Applications (1)

Application Number Title Priority Date Filing Date
DK472788A DK170978B1 (da) 1987-08-28 1988-08-24 Derivater af 2-azabicyklo [2,2,2]octan-3-carboxylsyre, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende sådanne

Country Status (16)

Country Link
US (1) US4959372A (da)
EP (1) EP0305297B1 (da)
JP (1) JPS6471875A (da)
AT (1) ATE52789T1 (da)
AU (1) AU612689B2 (da)
CA (1) CA1327800C (da)
DE (1) DE3860148D1 (da)
DK (1) DK170978B1 (da)
ES (1) ES2031616T3 (da)
FR (1) FR2619813B1 (da)
GR (1) GR3000677T3 (da)
IE (1) IE60505B1 (da)
NZ (1) NZ225943A (da)
OA (1) OA08754A (da)
PT (1) PT88357B (da)
ZA (1) ZA886368B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5458883A (en) * 1994-01-12 1995-10-17 Duke University Method of treating disorders of the eye
EP1233811A2 (en) * 1999-11-12 2002-08-28 Leo Rubin Methods for treating cardiac arrest or pulmonary hypertension and compositions for use therein comprising vasoactive intestinal polypeptide and cardiac device for electrical and chemical regulation and methods of use
JPWO2002076981A1 (ja) * 2001-03-26 2004-10-07 壽製薬株式会社 イソキヌクリジン誘導体及びその製造方法並びにこれを含有する医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung

Also Published As

Publication number Publication date
FR2619813A1 (fr) 1989-03-03
ATE52789T1 (de) 1990-06-15
ZA886368B (en) 1989-05-30
DK170978B1 (da) 1996-04-09
DK472788D0 (da) 1988-08-24
FR2619813B1 (fr) 1991-05-03
DE3860148D1 (de) 1990-06-21
GR3000677T3 (en) 1991-09-27
CA1327800C (fr) 1994-03-15
NZ225943A (en) 1990-06-26
OA08754A (fr) 1989-03-31
AU612689B2 (en) 1991-07-18
AU2159488A (en) 1989-03-09
JPS6471875A (en) 1989-03-16
IE60505B1 (en) 1994-07-27
PT88357A (pt) 1989-06-30
EP0305297A1 (fr) 1989-03-01
PT88357B (pt) 1995-03-31
IE882599L (en) 1989-02-28
ES2031616T3 (es) 1992-12-16
US4959372A (en) 1990-09-25
EP0305297B1 (fr) 1990-05-16

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