DK477278A - Fremgangsmaade til forbedring af stabiliseringen af meningokokpolysaccharid samt anvendelse af fremgangsmaaden - Google Patents

Fremgangsmaade til forbedring af stabiliseringen af meningokokpolysaccharid samt anvendelse af fremgangsmaaden

Info

Publication number
DK477278A
DK477278A DK477278A DK477278A DK477278A DK 477278 A DK477278 A DK 477278A DK 477278 A DK477278 A DK 477278A DK 477278 A DK477278 A DK 477278A DK 477278 A DK477278 A DK 477278A
Authority
DK
Denmark
Prior art keywords
procedure
meningokok
polysaccharide
stabilization
improving
Prior art date
Application number
DK477278A
Other languages
English (en)
Other versions
DK158006B (da
DK158006C (da
Inventor
G Guthoehrlein
T B Helting
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK477278A publication Critical patent/DK477278A/da
Publication of DK158006B publication Critical patent/DK158006B/da
Application granted granted Critical
Publication of DK158006C publication Critical patent/DK158006C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK477278A 1977-10-27 1978-10-26 Fremgangsmaade til stabilisering af toerret meningokokpolysaccharid DK158006C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2748132 1977-10-27
DE19772748132 DE2748132A1 (de) 1977-10-27 1977-10-27 Stabilisator fuer polysaccharid

Publications (3)

Publication Number Publication Date
DK477278A true DK477278A (da) 1979-04-28
DK158006B DK158006B (da) 1990-03-12
DK158006C DK158006C (da) 1990-08-06

Family

ID=6022367

Family Applications (1)

Application Number Title Priority Date Filing Date
DK477278A DK158006C (da) 1977-10-27 1978-10-26 Fremgangsmaade til stabilisering af toerret meningokokpolysaccharid

Country Status (11)

Country Link
US (1) US4206200A (da)
JP (1) JPS5470422A (da)
BE (1) BE871612A (da)
CA (1) CA1113861A (da)
DE (1) DE2748132A1 (da)
DK (1) DK158006C (da)
ES (1) ES474412A1 (da)
FI (1) FI61807B (da)
FR (1) FR2406999A1 (da)
GB (1) GB2009198B (da)
SE (1) SE447700B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
JPH0779694B2 (ja) * 1985-07-09 1995-08-30 カドラント バイオリソ−シズ リミテツド 蛋白質および同類品の保護
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
JPH03208485A (ja) * 1990-01-11 1991-09-11 Matsushita Electric Ind Co Ltd 文字放送受信装置
US5200399A (en) * 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
ATE416755T1 (de) * 1994-03-07 2008-12-15 Nektar Therapeutics Verfahren und zusammensetzung für die pulmonale darreichung von insulin
DE69530196T2 (de) 1994-06-02 2003-11-20 Elan Drug Delivery Ltd Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen
GB9508691D0 (en) 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US5876992A (en) * 1996-07-03 1999-03-02 Molecular Biology Resources, Inc. Method and formulation for stabilization of enzymes
US6306404B1 (en) 1998-07-14 2001-10-23 American Cyanamid Company Adjuvant and vaccine compositions containing monophosphoryl lipid A
FR2791895B1 (fr) * 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
US6635261B2 (en) 1999-07-13 2003-10-21 Wyeth Holdings Corporation Adjuvant and vaccine compositions containing monophosphoryl lipid A
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
KR100887429B1 (ko) 2001-10-22 2009-03-09 돔페 파르마 에스.피.에이. 초임계 유체 공정: 단백질 미세입자의 제조 및 그의 안정화
ES2616180T3 (es) * 2002-03-26 2017-06-09 Glaxosmithkline Biologicals Sa Sacáridos modificados con estabilidad mejorada en agua para su uso como medicamento
US20030124139A1 (en) * 2002-11-20 2003-07-03 Irina Esikova Compositions and methods for stabilizing biological molecules upon lyophilization
KR20130122988A (ko) 2005-03-14 2013-11-11 와이어쓰 엘엘씨 티게사이클린 조성물 및 이의 제조방법
PE20110072A1 (es) * 2005-06-27 2011-02-04 Glaxosmithkline Biolog Sa Composicion inmunogenica
GB0612854D0 (en) * 2006-06-28 2006-08-09 Novartis Ag Saccharide analysis
JP5721704B2 (ja) 2009-06-12 2015-05-20 マイクロニクス， インコーポレイテッド マイクロ流体デバイス内のｔａｑポリメラーゼを乾燥保存するための再水和可能なマトリックス
WO2010144683A2 (en) 2009-06-12 2010-12-16 Micronics, Inc. Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908614A (en) * 1954-08-10 1959-10-13 Glaxo Lab Ltd Use of dextran in freeze-drying process
US3135663A (en) * 1960-06-28 1964-06-02 Glaxo Group Ltd Vaccines
GB995362A (en) * 1962-05-11 1965-06-16 Smith Kline French Lab Improvements in or relating to freeze-drying biological material
DE1183629B (de) * 1962-12-21 1964-12-17 Behringwerke Ag Verfahren zur Stabilisierung biologisch aktiven Materials
US3567585A (en) * 1963-07-12 1971-03-02 Ciba Geigy Corp Process for obtaining bcg-cultures
DE1617350C3 (de) * 1967-06-22 1979-09-06 Behringwerke Ag, 3550 Marburg Verfahren zur Inaktivierung von biologischem Material
US3532790A (en) * 1968-02-23 1970-10-06 Canadian Patents Dev Somatic antigen vaccines from lysed inactivated bacteria and process for producing them
FR7461M (da) * 1968-06-19 1970-01-05
GB1218277A (en) * 1968-08-20 1971-01-06 Miles Lab Dry water-dispersible aluminium hydroxide gels
US3577527A (en) * 1969-01-27 1971-05-04 Us Navy Neisseria meningitidis antigen
US3599150A (en) * 1969-08-01 1971-08-10 Miles Lab Stabilized aluminum hydroxide suspensions
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
US3859434A (en) * 1973-01-08 1975-01-07 Canadian Patents Dev Meningococcal antigens

Also Published As

Publication number Publication date
JPS6310686B2 (da) 1988-03-08
DK158006B (da) 1990-03-12
FI61807B (fi) 1982-06-30
JPS5470422A (en) 1979-06-06
SE447700B (sv) 1986-12-08
CA1113861A (en) 1981-12-08
BE871612A (fr) 1979-04-27
DE2748132C2 (da) 1989-04-06
GB2009198B (en) 1982-10-27
FI783250A7 (fi) 1979-04-28
FR2406999A1 (fr) 1979-05-25
ES474412A1 (es) 1979-04-16
DE2748132A1 (de) 1979-05-03
US4206200A (en) 1980-06-03
SE7811083L (sv) 1979-04-28
DK158006C (da) 1990-08-06
GB2009198A (en) 1979-06-13
FR2406999B1 (da) 1982-11-12

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