DK506189A - Piperidinylbenzimidazoler eller et farmaceutisk acceptabelt salt deraf samt farmaceutisk praeparat indeholdende dem - Google Patents

Piperidinylbenzimidazoler eller et farmaceutisk acceptabelt salt deraf samt farmaceutisk praeparat indeholdende dem

Info

Publication number
DK506189A
DK506189A DK506189A DK506189A DK506189A DK 506189 A DK506189 A DK 506189A DK 506189 A DK506189 A DK 506189A DK 506189 A DK506189 A DK 506189A DK 506189 A DK506189 A DK 506189A
Authority
DK
Denmark
Prior art keywords
pharmaceutical
acceptable salt
preparations containing
benzimidazoles
piperidinyl
Prior art date
Application number
DK506189A
Other languages
English (en)
Other versions
DK506189D0 (da
Inventor
Albert Anthony Carr
John Michael Kane
Hsien Chang Cheng
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK506189D0 publication Critical patent/DK506189D0/da
Publication of DK506189A publication Critical patent/DK506189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Hydrogenated Pyridines (AREA)
DK506189A 1988-10-13 1989-10-12 Piperidinylbenzimidazoler eller et farmaceutisk acceptabelt salt deraf samt farmaceutisk praeparat indeholdende dem DK506189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/256,959 US4908372A (en) 1988-10-13 1988-10-13 Antihistaminic piperidinyl benzimidazoles

Publications (2)

Publication Number Publication Date
DK506189D0 DK506189D0 (da) 1989-10-12
DK506189A true DK506189A (da) 1990-04-14

Family

ID=22974308

Family Applications (1)

Application Number Title Priority Date Filing Date
DK506189A DK506189A (da) 1988-10-13 1989-10-12 Piperidinylbenzimidazoler eller et farmaceutisk acceptabelt salt deraf samt farmaceutisk praeparat indeholdende dem

Country Status (20)

Country Link
US (1) US4908372A (da)
EP (1) EP0363963B1 (da)
JP (1) JP2867151B2 (da)
KR (1) KR0157046B1 (da)
CN (1) CN1028103C (da)
AR (1) AR248018A1 (da)
AT (1) ATE121741T1 (da)
AU (1) AU619601B2 (da)
CA (1) CA2000468C (da)
DE (1) DE68922366T2 (da)
DK (1) DK506189A (da)
ES (1) ES2074067T3 (da)
FI (1) FI894834A7 (da)
HU (1) HU203340B (da)
IE (1) IE66112B1 (da)
IL (1) IL91952A (da)
NO (1) NO894086L (da)
NZ (1) NZ230956A (da)
PT (1) PT91968B (da)
ZA (1) ZA897676B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2022451C (en) * 1989-08-03 2001-01-23 Albert Anthony Carr Anti-psychotic piperidynl benzimidazole compounds
WO1992006086A1 (en) * 1990-10-01 1992-04-16 Janssen Pharmaceutica N.V. Novel 4-piperidinylcarbonyl derivatives
FR2668150B1 (fr) * 1990-10-17 1994-11-18 Theramex Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
FI932687L (fi) * 1990-12-14 1993-06-11 Merrell Dow Pharma Antiallergiska foereningar
TW263504B (da) * 1991-10-03 1995-11-21 Pfizer
AU3347493A (en) * 1992-01-09 1993-08-03 Janssen Pharmaceutica N.V. Pharmaceutically active substituted benzimidazole derivatives
WO1993016081A1 (en) * 1992-02-13 1993-08-19 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
DK0777666T3 (da) 1994-08-25 1999-09-27 Merrell Pharma Inc Substituerede piperidiner anvendelige ved behandling af allergiske sygdomme
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
JP2000507269A (ja) * 1996-03-15 2000-06-13 イーライ・リリー・アンド・カンパニー 一般かぜまたはアレルギー性鼻炎の処置方法
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
IL151533A0 (en) * 2000-02-29 2003-04-10 Mitsubishi Pharma Corp Novel cyclic amide derivatives
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP5067968B2 (ja) * 2004-10-07 2012-11-07 ビテ ファーマシューティカルズ， インコーポレイテッド ジアミノアルカンアスパラギン酸プロテアーゼ阻害剤
ZA200804550B (en) 2005-11-09 2009-08-26 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
JP2010503682A (ja) * 2006-09-18 2010-02-04 ビテ ファーマシューティカルズ， インコーポレイテッド レニン阻害剤としてのピペリジン誘導体
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
EP2167609A1 (en) * 2007-06-20 2010-03-31 Vitae Pharmaceuticals, Inc. Renin inhibitors
US20110160300A1 (en) * 2008-06-20 2011-06-30 Marlys Hammond Renin Inhibitors and Methods of Use Thereof
AU2009262319A1 (en) * 2008-06-26 2009-12-30 Vitae Pharmaceuticals, Inc. Salts of methyl 2-((R))-(3-chlorophenyl) ((R)-1-((S)-2- (methylamino)-3((R)-tetrahydro-2H-pyran-3-yl) propylcarbamoyl) piperidin-3-yl)methoxy)ethylcarbamate
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
US20110130711A1 (en) * 2009-11-19 2011-06-02 Follica, Inc. Hair growth treatment
EP2447263A1 (en) 2010-09-27 2012-05-02 Bioprojet Benzazole derivatives as histamine H4 receptor ligands
CA2874303C (en) 2012-06-11 2020-10-13 Ucb Biopharma Sprl Tnf -alpha modulating benz imidazoles
GB201510758D0 (en) 2015-06-18 2015-08-05 Ucb Biopharma Sprl Novel TNFa structure for use in therapy
GB201621907D0 (en) 2016-12-21 2017-02-01 Ucb Biopharma Sprl And Sanofi Antibody epitope

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4285957A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
CA2022451C (en) * 1989-08-03 2001-01-23 Albert Anthony Carr Anti-psychotic piperidynl benzimidazole compounds

Also Published As

Publication number Publication date
CN1041940A (zh) 1990-05-09
DK506189D0 (da) 1989-10-12
AR248018A1 (es) 1995-05-31
FI894834A0 (fi) 1989-10-12
HUT51613A (en) 1990-05-28
NO894086L (no) 1990-04-17
FI894834A7 (fi) 1990-04-14
CA2000468C (en) 2000-03-21
JPH02134377A (ja) 1990-05-23
CN1028103C (zh) 1995-04-05
HU203340B (en) 1991-07-29
JP2867151B2 (ja) 1999-03-08
NZ230956A (en) 1991-03-26
AU4273589A (en) 1990-04-26
ES2074067T3 (es) 1995-09-01
AU619601B2 (en) 1992-01-30
CA2000468A1 (en) 1990-04-13
IL91952A0 (en) 1990-06-10
NO894086D0 (no) 1989-10-12
US4908372A (en) 1990-03-13
IE66112B1 (en) 1995-12-13
KR0157046B1 (ko) 1998-11-16
IE893294L (en) 1990-04-13
ZA897676B (en) 1990-07-25
EP0363963B1 (en) 1995-04-26
DE68922366T2 (de) 1995-09-28
ATE121741T1 (de) 1995-05-15
KR900006318A (ko) 1990-05-07
IL91952A (en) 1994-06-24
HU895305D0 (en) 1990-01-28
PT91968B (pt) 1995-05-31
PT91968A (pt) 1990-04-30
DE68922366D1 (de) 1995-06-01
EP0363963A1 (en) 1990-04-18

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