NO894086L - Fremgangsmaate for fremstilling av piperidinylbenzimidazoler. - Google Patents

Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.

Info

Publication number: NO894086L
Authority: NO; Norway
Prior art keywords: procedure; benzimidazoles; piperidinyl; piperidinyl benzimidazoles
Prior art date: 1988-10-13

Application number

NO89894086A

Other languages

English (en)

Other versions

NO894086D0 (no

Inventor

Albert Anthony Carr

John Michael Kane

Hsien Cheng Cheng

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-13

Filing date

1989-10-12

Publication date

1990-04-17

1989-10-12 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-10-12 Publication of NO894086D0 publication Critical patent/NO894086D0/no

1990-04-17 Publication of NO894086L publication Critical patent/NO894086L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

NO89894086A 1988-10-13 1989-10-12 Fremgangsmaate for fremstilling av piperidinylbenzimidazoler. NO894086L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/256,959 US4908372A (en)	1988-10-13	1988-10-13	Antihistaminic piperidinyl benzimidazoles

Publications (2)

Publication Number	Publication Date
NO894086D0 NO894086D0 (no)	1989-10-12
NO894086L true NO894086L (no)	1990-04-17

Family

ID=22974308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO89894086A NO894086L (no)	1988-10-13	1989-10-12	Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.

Country Status (20)

Country	Link
US (1)	US4908372A (no)
EP (1)	EP0363963B1 (no)
JP (1)	JP2867151B2 (no)
KR (1)	KR0157046B1 (no)
CN (1)	CN1028103C (no)
AR (1)	AR248018A1 (no)
AT (1)	ATE121741T1 (no)
AU (1)	AU619601B2 (no)
CA (1)	CA2000468C (no)
DE (1)	DE68922366T2 (no)
DK (1)	DK506189A (no)
ES (1)	ES2074067T3 (no)
FI (1)	FI894834A7 (no)
HU (1)	HU203340B (no)
IE (1)	IE66112B1 (no)
IL (1)	IL91952A (no)
NO (1)	NO894086L (no)
NZ (1)	NZ230956A (no)
PT (1)	PT91968B (no)
ZA (1)	ZA897676B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2022451C (en) *	1989-08-03	2001-01-23	Albert Anthony Carr	Anti-psychotic piperidynl benzimidazole compounds
WO1992006086A1 (en) *	1990-10-01	1992-04-16	Janssen Pharmaceutica N.V.	Novel 4-piperidinylcarbonyl derivatives
FR2668150B1 (fr) *	1990-10-17	1994-11-18	Theramex	Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
CA2097317C (en) *	1990-12-14	2002-02-12	Albert A. Carr	Antiallergic piperdinyl benzimidazoles
TW263504B (no) *	1991-10-03	1995-11-21	Pfizer
AU3347493A (en) *	1992-01-09	1993-08-03	Janssen Pharmaceutica N.V.	Pharmaceutically active substituted benzimidazole derivatives
WO1993016081A1 (en) *	1992-02-13	1993-08-19	Merrell Dow Pharmaceuticals Inc.	Piperidinyl thiacyclic derivatives
MX9701305A (es)	1994-08-25	1998-05-31	Merrell Pharma Inc	Piperidinas sustituidas novedosas utiles para el tratamiento de enfermedades alergicas.
US6211199B1 (en)	1995-11-17	2001-04-03	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) *	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
CN1218368A (zh) *	1996-03-15	1999-06-02	伊莱利利公司	治疗感冒或过敏性鼻炎的方法
US5869497A (en) *	1996-03-15	1999-02-09	Eli Lilly And Company	Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
NZ521576A (en) *	2000-02-29	2005-06-24	Mitsubishi Pharma Corp	Novel cyclic amide derivatives
TW200517114A (en)	2003-10-15	2005-06-01	Combinatorx Inc	Methods and reagents for the treatment of immunoinflammatory disorders
AU2005294123C1 (en) *	2004-10-07	2010-01-21	Vitae Pharmaceuticals, Inc.	Diaminoalkane aspartic protease inhibitors
WO2007056457A2 (en)	2005-11-09	2007-05-18	Combinatorx, Incorporated	Methods, compositions, and kits for the treatment of medical conditions
TWI411607B (zh) *	2005-11-14	2013-10-11	Vitae Pharmaceuticals Inc	天門冬胺酸蛋白酶抑制劑
JP2010503682A (ja) *	2006-09-18	2010-02-04	ビテファーマシューティカルズ，インコーポレイテッド	レニン阻害剤としてのピペリジン誘導体
CL2007002689A1 (es) *	2006-09-18	2008-04-18	Vitae Pharmaceuticals Inc	Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
WO2008156817A2 (en) *	2007-06-20	2008-12-24	Vitae Pharmaceuticals, Inc.	Renin inhibitors
EP2167609A1 (en) *	2007-06-20	2010-03-31	Vitae Pharmaceuticals, Inc.	Renin inhibitors
JP2011525488A (ja) *	2008-06-20	2011-09-22	ヴァイティーファーマシューティカルズ，インコーポレイテッド	レニン阻害剤およびその使用方法
CN102088850A (zh) *	2008-06-26	2011-06-08	生命医药公司	甲基2-((r)-(3-氯苯基)((r)-1-((s)-2-(甲氨基)-3((r)-四氢-2h-吡喃-3-基)丙基氨甲酰基)哌啶-3-基)甲氧基)氨基甲酸乙酯的盐
WO2010021681A2 (en) *	2008-08-18	2010-02-25	Combinatorx (Singapore) Pte. Ltd.	Compositions and methods for treatment of viral diseases
AR077692A1 (es) *	2009-08-06	2011-09-14	Vitae Pharmaceuticals Inc	Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
US20110130711A1 (en) *	2009-11-19	2011-06-02	Follica, Inc.	Hair growth treatment
EP2447263A1 (en) *	2010-09-27	2012-05-02	Bioprojet	Benzazole derivatives as histamine H4 receptor ligands
US9550737B2 (en)	2012-06-11	2017-01-24	Ucb Biopharma Sprl	TNF -α modulating benzimidazoles
GB201510758D0 (en)	2015-06-18	2015-08-05	Ucb Biopharma Sprl	Novel TNFa structure for use in therapy
GB201621907D0 (en)	2016-12-21	2017-02-01	Ucb Biopharma Sprl And Sanofi	Antibody epitope

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3878217A (en) *	1972-01-28	1975-04-15	Richardson Merrell Inc	Alpha-aryl-4-substituted piperidinoalkanol derivatives
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
US4254129A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives
US4285957A (en) *	1979-04-10	1981-08-25	Richardson-Merrell Inc.	1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
CA2022451C (en) *	1989-08-03	2001-01-23	Albert Anthony Carr	Anti-psychotic piperidynl benzimidazole compounds

1988
- 1988-10-13 US US07/256,959 patent/US4908372A/en not_active Expired - Lifetime
1989
- 1989-10-09 ZA ZA897676A patent/ZA897676B/xx unknown
- 1989-10-09 AR AR89315117A patent/AR248018A1/es active
- 1989-10-10 AU AU42735/89A patent/AU619601B2/en not_active Ceased
- 1989-10-10 NZ NZ230956A patent/NZ230956A/en unknown
- 1989-10-11 CA CA002000468A patent/CA2000468C/en not_active Expired - Fee Related
- 1989-10-11 KR KR1019890014536A patent/KR0157046B1/ko not_active Expired - Fee Related
- 1989-10-11 IL IL9195289A patent/IL91952A/en not_active IP Right Cessation
- 1989-10-12 DE DE68922366T patent/DE68922366T2/de not_active Expired - Fee Related
- 1989-10-12 AT AT89118987T patent/ATE121741T1/de not_active IP Right Cessation
- 1989-10-12 EP EP89118987A patent/EP0363963B1/en not_active Expired - Lifetime
- 1989-10-12 NO NO89894086A patent/NO894086L/no unknown
- 1989-10-12 CN CN89107837A patent/CN1028103C/zh not_active Expired - Fee Related
- 1989-10-12 IE IE329489A patent/IE66112B1/en not_active IP Right Cessation
- 1989-10-12 FI FI894834A patent/FI894834A7/fi not_active Application Discontinuation
- 1989-10-12 ES ES89118987T patent/ES2074067T3/es not_active Expired - Lifetime
- 1989-10-12 DK DK506189A patent/DK506189A/da not_active Application Discontinuation
- 1989-10-12 PT PT91968A patent/PT91968B/pt not_active IP Right Cessation
- 1989-10-12 HU HU895305A patent/HU203340B/hu not_active IP Right Cessation
- 1989-10-13 JP JP1267959A patent/JP2867151B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE121741T1 (de)	1995-05-15
FI894834A0 (fi)	1989-10-12
DK506189D0 (da)	1989-10-12
JP2867151B2 (ja)	1999-03-08
ZA897676B (en)	1990-07-25
KR900006318A (ko)	1990-05-07
CA2000468A1 (en)	1990-04-13
DE68922366T2 (de)	1995-09-28
CN1028103C (zh)	1995-04-05
CN1041940A (zh)	1990-05-09
HU895305D0 (en)	1990-01-28
FI894834A7 (fi)	1990-04-14
AU4273589A (en)	1990-04-26
IE893294L (en)	1990-04-13
PT91968B (pt)	1995-05-31
HUT51613A (en)	1990-05-28
DK506189A (da)	1990-04-14
IL91952A0 (en)	1990-06-10
US4908372A (en)	1990-03-13
IL91952A (en)	1994-06-24
ES2074067T3 (es)	1995-09-01
EP0363963B1 (en)	1995-04-26
CA2000468C (en)	2000-03-21
HU203340B (en)	1991-07-29
JPH02134377A (ja)	1990-05-23
AU619601B2 (en)	1992-01-30
KR0157046B1 (ko)	1998-11-16
IE66112B1 (en)	1995-12-13
NZ230956A (en)	1991-03-26
NO894086D0 (no)	1989-10-12
AR248018A1 (es)	1995-05-31
PT91968A (pt)	1990-04-30
DE68922366D1 (de)	1995-06-01
EP0363963A1 (en)	1990-04-18

Publication	Publication Date	Title
NO894086D0 (no)	1989-10-12	Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.
NO903190L (no)	1991-01-21	Fremgangsmaate for klorering av sukrose-b-estere.
DE3781845D1 (de)	1992-10-29	Benzimidazol-derivate.
NL300161I2 (nl)	2005-02-01	Carbostyrilderivaten.
FI890866A7 (fi)	1989-08-24	Piperidinderivat.
NO872831D0 (no)	1987-07-07	Fremgangsmaate for fremstilling av nitrofuranderivater.
ATE124397T1 (de)	1995-07-15	Piperidin-derivate.
DE3768992D1 (de)	1991-05-08	Benzimidazol-derivate.
NO890579L (no)	1989-08-14	((5(6) (1h-azol-1-ylmetyl)benzimidazol)karbamater.
FI885243A0 (fi)	1988-11-11	Foerfarande foer framstaellning av stabiliserade olefinpolymerer.
DE58906668D1 (de)	1994-02-24	Spannzange.
FI902336A0 (fi)	1990-05-10	Anordning foer framstaellning av en fristaoende kiselkristall.
FI892761A0 (fi)	1989-06-06	Expressionsvektorer foer framstaellning av ofusionerade proteiner i mikroorganismer.
FI891124A0 (fi)	1989-03-09	Anordning foer framstaellning av en flerskiktstraeskiva.
FI880137A7 (fi)	1989-07-14	Anlaeggning i valsverket av en superkalander.
FI883555A7 (fi)	1989-01-30	Benzimidazolderivat.
FI894582A0 (fi)	1989-09-27	Borranordning foer framstaellning av borrhaol med bakskaerning.
FI895021A0 (fi)	1989-10-23	Anordning foer utfoerande av membransepareringsprocesser.
FI890717L (fi)	1989-09-18	Foerfarande foer framstaellning av (r)-glycidylestrar.
DE58901804D1 (de)	1992-08-13	Spannzange.
NO892714L (no)	1990-01-02	Substituerte azacykloheksylderivater.
NO892006D0 (no)	1989-05-19	Anordning for dannelse av oppstaaende kant.
FI881824L (fi)	1988-10-22	Dihydropyridinderivat.
FI891507L (fi)	1989-10-21	Staell foer solfaongare.
FI882557A0 (fi)	1988-05-31	Anordning foer smoerjning av en kuggvaexel.