DK514182A - Fremgangsmaade til fremstilling af n-substituerede 2-pyridylindoler eller n-oxider eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af n-substituerede 2-pyridylindoler eller n-oxider eller salte deraf Download PDF

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Publication number
DK514182A
DK514182A DK514182A DK514182A DK514182A DK 514182 A DK514182 A DK 514182A DK 514182 A DK514182 A DK 514182A DK 514182 A DK514182 A DK 514182A DK 514182 A DK514182 A DK 514182A
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DK
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Prior art keywords
oxides
salts
substituted
procedure
preparation
Prior art date
Application number
DK514182A
Other languages
English (en)
Other versions
DK169104B1 (da
Inventor
Harris Burt Renfroe
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK514182A publication Critical patent/DK514182A/da
Application granted granted Critical
Publication of DK169104B1 publication Critical patent/DK169104B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK514182A 1981-11-19 1982-11-18 Analogifremgangsmåde til fremstilling af N-substituerede 2-pyridylindoler eller salte deraf DK169104B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32301881A 1981-11-19 1981-11-19
US32301881 1981-11-19

Publications (2)

Publication Number Publication Date
DK514182A true DK514182A (da) 1983-05-20
DK169104B1 DK169104B1 (da) 1994-08-15

Family

ID=23257445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK514182A DK169104B1 (da) 1981-11-19 1982-11-18 Analogifremgangsmåde til fremstilling af N-substituerede 2-pyridylindoler eller salte deraf

Country Status (22)

Country Link
EP (1) EP0080154B1 (da)
JP (1) JPS5892677A (da)
KR (1) KR880002010B1 (da)
AR (3) AR241428A1 (da)
AT (1) ATE15196T1 (da)
AU (1) AU564233B2 (da)
CA (1) CA1197249A (da)
DD (1) DD204924A5 (da)
DE (1) DE3265892D1 (da)
DK (1) DK169104B1 (da)
ES (4) ES8501755A1 (da)
FI (1) FI75344C (da)
GB (1) GB2111050B (da)
GR (1) GR77035B (da)
HU (1) HU190425B (da)
IE (1) IE54156B1 (da)
IL (1) IL67284A (da)
NO (1) NO159929C (da)
NZ (1) NZ202551A (da)
PH (1) PH19212A (da)
PT (1) PT75870B (da)
ZA (1) ZA828505B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4675332A (en) * 1984-12-10 1987-06-23 Warner-Lambert Company Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB9319100D0 (en) * 1993-09-15 1993-11-03 Pfizer Ltd 3-(3-pyridinyl)h-indoles
CA2140722A1 (en) * 1994-01-24 1995-07-25 Joseph A. Jakubowski Beta-carboline thromboxane synthase inhibitors
US6828344B1 (en) * 1998-02-25 2004-12-07 Genetics Institute, Llc Inhibitors of phospholipase enzymes
GB0307891D0 (en) * 2003-04-04 2003-05-14 Angeletti P Ist Richerche Bio Chemical compounds,compositions and uses
AR072297A1 (es) * 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
AU2018386201A1 (en) * 2017-12-15 2020-07-30 Bristol-Myers Squibb Company Substituted indole ether compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468894A (en) * 1966-11-29 1969-09-23 Geigy Chem Corp Certain 2-pyridyl-substituted indole derivatives
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
KR880002010B1 (ko) 1988-10-12
NO823869L (no) 1983-05-20
ES530126A0 (es) 1985-11-16
ES530128A0 (es) 1985-12-01
NZ202551A (en) 1985-11-08
CA1197249A (en) 1985-11-26
KR840002368A (ko) 1984-06-25
GB2111050B (en) 1985-09-11
JPH029031B2 (da) 1990-02-28
DK169104B1 (da) 1994-08-15
FI75344B (fi) 1988-02-29
FI823938L (fi) 1983-05-20
DE3265892D1 (en) 1985-10-03
AU564233B2 (en) 1987-08-06
GB2111050A (en) 1983-06-29
JPS5892677A (ja) 1983-06-02
ES8601962A1 (es) 1985-11-16
DD204924A5 (de) 1983-12-14
ES8608508A1 (es) 1986-06-16
ZA828505B (en) 1983-09-28
AR243177A1 (es) 1993-07-30
AR241428A1 (es) 1992-07-31
HU190425B (en) 1986-09-29
EP0080154B1 (de) 1985-08-28
ES517439A0 (es) 1984-12-01
AR243519A1 (es) 1993-08-31
NO159929B (no) 1988-11-14
IE54156B1 (en) 1989-07-05
PT75870A (en) 1982-12-01
AU9067582A (en) 1983-05-26
GR77035B (da) 1984-09-04
EP0080154A3 (en) 1983-09-28
EP0080154A2 (de) 1983-06-01
FI75344C (fi) 1988-06-09
PT75870B (en) 1986-01-21
PH19212A (en) 1986-02-04
NO159929C (no) 1989-02-22
FI823938A0 (fi) 1982-11-17
ES8602750A1 (es) 1985-12-01
ES530127A0 (es) 1986-06-16
ATE15196T1 (de) 1985-09-15
ES8501755A1 (es) 1984-12-01
IL67284A (en) 1986-03-31

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed