DK520284A - Enzyminhibering - Google Patents

Enzyminhibering Download PDF

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Publication number
DK520284A
DK520284A DK520284A DK520284A DK520284A DK 520284 A DK520284 A DK 520284A DK 520284 A DK520284 A DK 520284A DK 520284 A DK520284 A DK 520284A DK 520284 A DK520284 A DK 520284A
Authority
DK
Denmark
Prior art keywords
pct
enzyme inhibition
sec
date
pub
Prior art date
Application number
DK520284A
Other languages
English (en)
Other versions
DK520284D0 (da
Inventor
Michael Szelke
David Michael Jones
Martin Andrew Brydson
Original Assignee
Ferring Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Ab filed Critical Ferring Ab
Publication of DK520284D0 publication Critical patent/DK520284D0/da
Publication of DK520284A publication Critical patent/DK520284A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Saccharide Compounds (AREA)
DK520284A 1983-03-04 1984-11-01 Enzyminhibering DK520284A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838305985A GB8305985D0 (en) 1983-03-04 1983-03-04 Enzyme inhibition
PCT/GB1984/000063 WO1984003507A1 (en) 1983-03-04 1984-02-28 Enzyme inhibition

Publications (2)

Publication Number Publication Date
DK520284D0 DK520284D0 (da) 1984-11-01
DK520284A true DK520284A (da) 1984-11-01

Family

ID=10538985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK520284A DK520284A (da) 1983-03-04 1984-11-01 Enzyminhibering

Country Status (13)

Country Link
US (2) US4638047A (da)
EP (1) EP0118280B1 (da)
JP (1) JPS60500870A (da)
AT (1) ATE44533T1 (da)
AU (1) AU596783B2 (da)
CA (1) CA1322078C (da)
DE (1) DE3478928D1 (da)
DK (1) DK520284A (da)
ES (1) ES530262A0 (da)
FI (1) FI88398C (da)
GB (1) GB8305985D0 (da)
IE (1) IE56958B1 (da)
WO (1) WO1984003507A1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8305985D0 (en) * 1983-03-04 1983-04-07 Szelke M Enzyme inhibition
US4812442A (en) * 1984-05-29 1989-03-14 Merck & Co., Inc. Tripeptide renin inhibitors
DE3438545A1 (de) * 1984-10-20 1986-04-24 Merck Patent Gmbh, 6100 Darmstadt Peptide
DE3512128A1 (de) * 1985-04-03 1986-10-09 Merck Patent Gmbh, 6100 Darmstadt Peptide
US4705778A (en) * 1985-10-22 1987-11-10 Sri International Orally active LHRH analogs
DE3540495A1 (de) * 1985-11-15 1987-05-21 Merck Patent Gmbh Aminosaeurederivate
US6005071A (en) * 1987-01-23 1999-12-21 Merrell Pharmaceuticals Inc. Anticoagulant peptides
US5789540A (en) * 1987-01-23 1998-08-04 Merrell Pharmaceuticals Inc. Anticoagulant peptides
US4859654A (en) * 1987-07-01 1989-08-22 Pfizer Inc. Homocyclostatine and cyclostatine containing polypeptides as antihypertensive agents
US4994270A (en) * 1988-04-11 1991-02-19 Eli Lilly And Company A54145 antibiotics and process for their production
US5028590A (en) * 1988-04-11 1991-07-02 Eli Lilly And Company Derivatives of A54145 cyclic peptides
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6313096B1 (en) 1988-04-28 2001-11-06 Trigen Limited Inhibitors of trypsin-like enzymes
US5574014A (en) * 1988-04-28 1996-11-12 Thrombosis Research Institute Inhibitors of trypsin-like enzymes
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US4994367A (en) * 1988-10-07 1991-02-19 East Carolina University Extended shelf life platelet preparations and process for preparing the same
US5194424A (en) * 1988-12-27 1993-03-16 Gruppo Lepetit Spa C63 -amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics
EP0462229A4 (en) * 1989-05-02 1992-03-11 Genelabs Incorporated Chemically modified cd4 peptide fragments having anti-retroviral properties
US5187155A (en) * 1989-06-23 1993-02-16 Board Of Regents, The University Of Texas System Anticoagulant peptides
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
NZ235564A (en) * 1989-10-13 1993-10-26 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical compositions
US5338723A (en) * 1989-10-13 1994-08-16 Merck & Co., Inc. Fibrinogen receptor antagonists
US5190919A (en) * 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
ATE160356T1 (de) * 1990-06-15 1997-12-15 Ca Nat Research Council Thrombin-inhibitoren mit einer hirudin-ähnlichen sequenz
DE69227895D1 (de) * 1991-02-04 1999-01-28 Akzo Nobel Nv FAKTOR IIa INHIBITOREN
WO1993003748A1 (en) * 1991-08-13 1993-03-04 Temple University - Of The Commonwealth System Of Higher Education Modulation of blood pressure and inhibition of platelet activation with kininogen fragment
SE9102462D0 (sv) * 1991-08-28 1991-08-28 Astra Ab New isosteric peptides
KR100358209B1 (ko) * 1992-07-20 2003-01-24 듀크 유니버시티 Hiv복제를저해하는조성물
US5637599A (en) * 1994-06-17 1997-06-10 Corvas International, Inc. Arginine mimic derivatives as enzyme inhibitors
DE4421052A1 (de) 1994-06-17 1995-12-21 Basf Ag Neue Thrombininhibitoren, ihre Herstellung und Verwendung
GB9502985D0 (en) * 1995-02-16 1995-04-05 Thrombosis Res Inst Enzyme inhibitors
US6030972A (en) * 1995-02-17 2000-02-29 Basf Aktiengesellschaft Dipeptide amidines as thrombin inhibitors
CA2221865C (en) * 1995-06-09 2007-12-11 The Regents Of The University Of Michigan Bradykinin analogs as selective thrombin inhibitors
US6982249B1 (en) 1997-04-23 2006-01-03 The Regents Of The University Of Michigan Bradykinin analogs as selective inhibitors of cell activation
JP2002501081A (ja) 1998-01-26 2002-01-15 ビーエーエスエフ アクチェンゲゼルシャフト トロンビンインヒビター
DE10254993A1 (de) * 2002-11-26 2004-06-09 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Säureamidarginine und deren Ester sowie deren Verwendung zur Konservierung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058077B (en) * 1979-06-08 1983-03-09 Szelke M Enkephalin analogues
NO812612L (no) * 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
GB8305985D0 (en) * 1983-03-04 1983-04-07 Szelke M Enzyme inhibition
US4629724A (en) * 1984-12-03 1986-12-16 E. R. Squibb & Sons, Inc. Amino acid ester and amide renin inhibitors

Also Published As

Publication number Publication date
AU596783B2 (en) 1990-05-17
FI88398C (fi) 1993-05-10
JPS60500870A (ja) 1985-06-06
ATE44533T1 (de) 1989-07-15
DE3478928D1 (en) 1989-08-17
EP0118280A1 (en) 1984-09-12
FI844230L (fi) 1984-10-29
WO1984003507A1 (en) 1984-09-13
FI844230A0 (fi) 1984-10-29
IE840474L (en) 1984-09-04
ES8602849A1 (es) 1985-12-01
US4638047A (en) 1987-01-20
ES530262A0 (es) 1985-12-01
DK520284D0 (da) 1984-11-01
AU2651684A (en) 1984-09-28
IE56958B1 (en) 1992-02-12
GB8305985D0 (en) 1983-04-07
FI88398B (fi) 1993-01-29
EP0118280B1 (en) 1989-07-12
CA1322078C (en) 1993-09-07
US4772686A (en) 1988-09-20

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment