DK523078A - Biologisk aktive amider fremgangsmaade til deres fremstilling samt deres anvendelse - Google Patents

Biologisk aktive amider fremgangsmaade til deres fremstilling samt deres anvendelse

Info

Publication number
DK523078A
DK523078A DK523078A DK523078A DK523078A DK 523078 A DK523078 A DK 523078A DK 523078 A DK523078 A DK 523078A DK 523078 A DK523078 A DK 523078A DK 523078 A DK523078 A DK 523078A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
biologically active
active amides
amides
Prior art date
Application number
DK523078A
Other languages
English (en)
Other versions
DK149612B (da
DK149612C (da
Inventor
S Wilkinson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK523078A publication Critical patent/DK523078A/da
Publication of DK149612B publication Critical patent/DK149612B/da
Application granted granted Critical
Publication of DK149612C publication Critical patent/DK149612C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675—Beta-endorphins
    • C07K14/6755—Beta-endorphins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK523078A 1977-11-24 1978-11-23 Analogifremgangsmaade til fremstilling af et enkephalinanalogt pentapeptidderivat eller farmakologisk og farmaceutisk acceptable salte eller syreadditionssalte deraf DK149612C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB48980/77A GB1604850A (en) 1977-11-24 1977-11-24 Biologically active peptides
GB4898077 1977-11-24

Publications (3)

Publication Number Publication Date
DK523078A true DK523078A (da) 1979-05-25
DK149612B DK149612B (da) 1986-08-11
DK149612C DK149612C (da) 1987-01-26

Family

ID=10450679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK523078A DK149612C (da) 1977-11-24 1978-11-23 Analogifremgangsmaade til fremstilling af et enkephalinanalogt pentapeptidderivat eller farmakologisk og farmaceutisk acceptable salte eller syreadditionssalte deraf

Country Status (20)

Country Link
US (5) US4244944A (da)
EP (1) EP0002236B1 (da)
JP (1) JPS5492938A (da)
KR (3) KR860000453B1 (da)
AT (1) AT386211B (da)
AU (1) AU530985B2 (da)
CA (1) CA1197235A (da)
DE (1) DE2862477D1 (da)
DK (1) DK149612C (da)
ES (1) ES475324A1 (da)
FI (1) FI70415C (da)
GB (1) GB1604850A (da)
HU (1) HU186729B (da)
IE (1) IE47517B1 (da)
IL (1) IL56028A (da)
IT (1) IT1106143B (da)
MY (1) MY8500260A (da)
PL (1) PL123797B1 (da)
SU (1) SU1470199A3 (da)
ZA (1) ZA786598B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI770219A7 (da) 1976-02-02 1977-08-03 Sandoz Ag
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
DE3163199D1 (en) * 1980-07-17 1984-05-24 Sandoz Ag Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
DE3267380D1 (en) * 1981-06-22 1985-12-19 Ici Plc Peptides and pseudopeptides in which the n terminus bears two substituents
US4380535A (en) * 1981-09-23 1983-04-19 American Home Products Corporation Enkephalin degrading enzyme inhibitors
US4492779A (en) * 1981-12-07 1985-01-08 Thiokol Corporation Aramid polymer and powder filler reinforced elastomeric composition for use as a rocket motor insulation
ATE25090T1 (de) * 1982-02-05 1987-02-15 Wellcome Found Pharmazeutische verbindungen, deren herstellung, anwendung, deren zwischenverbindungen und herstellung.
ATE37552T1 (de) * 1982-10-18 1988-10-15 Ici Plc Peptid- und pseudopeptid-derivate.
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
GB8608818D0 (en) * 1986-04-11 1986-05-14 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
GB8616741D0 (en) * 1986-07-09 1986-08-13 Wellcome Found Pharmacologically active compounds
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US5156787A (en) * 1991-01-29 1992-10-20 Booher Benjamin V Pultrusion method of making brake linings
USRE37548E1 (en) 1991-08-12 2002-02-19 Bill J. Hays Clutch design and manufacture
US5482772A (en) 1992-12-28 1996-01-09 Kimberly-Clark Corporation Polymeric strands including a propylene polymer composition and nonwoven fabric and articles made therewith
US6488649B1 (en) 1998-11-24 2002-12-03 Edward M. Lichten Implant device
IL165365A0 (en) 2004-11-24 2006-01-15 Q Core Ltd Finger-type peristaltic pump
WO2007121704A2 (de) * 2006-04-21 2007-11-01 Luk Lamellen Und Kupplungsbau Beteiligungs Kg Mehrschichtiger, insbesondere zweischichtiger kupplunqsbelag sowie verfahren zu dessen herstellung
US8005603B2 (en) 2007-09-27 2011-08-23 Continental Controls Corporation Fuel control system and method for gas engines

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1577115A (en) * 1976-07-27 1980-10-22 Reckitt & Colmann Prod Ltd Container closure units
NZ183712A (en) * 1976-04-08 1979-10-25 Ici Ltd Polypeptide analogues of enkephalins, and pharmaceutical compositions
US4028319A (en) * 1976-05-07 1977-06-07 G. D. Searle & Co. 2 and 3-substituted enkephalins
US4123523A (en) * 1976-06-21 1978-10-31 Imperial Chemical Industries Limited Analgesic and sedative polypeptides
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
US4092304A (en) * 1976-08-09 1978-05-30 G. D. Searle & Co. 4-Substituted enkephalin derivatives
SE7709806L (sv) * 1976-09-01 1978-03-02 Coy David Howard Forfarande for framstellning av peptider
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
US4128541A (en) * 1976-12-27 1978-12-05 American Home Products Corporation Pentapeptide with morphine- like activity
DE2819277A1 (de) * 1977-05-16 1978-11-23 Sandoz Ag Neue polypeptidderivate, ihre herstellung und verwendung
US4127523A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel undecapeptides, intermediates therefor, and compositions and methods employing said undecapeptides
US4127533A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides
US4127532A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heptapeptides, intermediates therefor, and compositions and methods employing said heptapeptides
US4127531A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexapeptides, intermediates therefor, and compositions and methods employing said hexapeptides
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
US4103005A (en) * 1977-10-20 1978-07-25 Hoffmann-La Roche Inc. Novel-enkephalin analogs

Also Published As

Publication number Publication date
JPS5492938A (en) 1979-07-23
FI783589A7 (fi) 1979-05-25
US4362717A (en) 1982-12-07
AT386211B (de) 1988-07-25
EP0002236A1 (en) 1979-06-13
PL211164A1 (pl) 1979-12-17
FI70415C (fi) 1986-09-19
ES475324A1 (es) 1979-12-01
IT1106143B (it) 1985-11-11
KR830000214A (ko) 1983-03-30
KR830000683A (ko) 1983-04-18
DE2862477D1 (en) 1986-03-20
EP0002236B1 (en) 1986-02-05
KR880002608B1 (ko) 1988-12-04
IL56028A0 (en) 1979-01-31
HU186729B (en) 1985-09-30
IT7852041A0 (it) 1978-11-23
DK149612B (da) 1986-08-11
DK149612C (da) 1987-01-26
US4346083A (en) 1982-08-24
AU4186578A (en) 1979-05-31
AU530985B2 (en) 1983-08-04
IL56028A (en) 1984-03-30
FI70415B (fi) 1986-03-27
US4363800A (en) 1982-12-14
SU1470199A3 (ru) 1989-03-30
KR830000215A (ko) 1983-03-30
KR860000453B1 (ko) 1986-04-26
IE782317L (en) 1979-05-24
GB1604850A (en) 1981-12-16
US4343795A (en) 1982-08-10
ATA836278A (de) 1987-12-15
US4244944A (en) 1981-01-13
IE47517B1 (en) 1984-04-04
MY8500260A (en) 1985-12-31
ZA786598B (en) 1980-06-25
JPS6318600B2 (da) 1988-04-19
PL123797B1 (en) 1982-11-30
KR880002609B1 (ko) 1988-12-04
CA1197235A (en) 1985-11-26

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