DK524884A - Farmaceutiske praeparater indeholdende phosphatidylserin og fremgangsmaade til fremstilling deraf - Google Patents

Farmaceutiske praeparater indeholdende phosphatidylserin og fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number: DK524884A
Authority: DK; Denmark
Prior art keywords: phosphaty; dylserine; procedures; preparing; pharmaceutical preparations
Prior art date: 1983-11-17

Application number

DK524884A

Other languages

English (en)

Other versions

DK168271B1 (da

DK524884D0 (da

Inventor

Francesco Della Valle

Aurelio Romeo

Original Assignee

Fidia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-17

Filing date

1984-11-02

Publication date

1985-05-18

1984-11-02 Application filed by Fidia Spa filed Critical Fidia Spa

1984-11-02 Publication of DK524884D0 publication Critical patent/DK524884D0/da

1985-05-18 Publication of DK524884A publication Critical patent/DK524884A/da

1994-03-07 Application granted granted Critical

1994-03-07 Publication of DK168271B1 publication Critical patent/DK168271B1/da

Links

238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 2
150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 2
TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 abstract 1
ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
230000015271 coagulation Effects 0.000 abstract 1
238000005345 coagulation Methods 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Dispersion Chemistry (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Polymers & Plastics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Epoxy Resins (AREA)
Heat Treatment Of Steel (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK524884A 1983-11-17 1984-11-02 Farmaceutiske præparater indeholdende phosphatidylserin og fremgangsmåde til fremstilling deraf DK168271B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT4935583		1983-11-17
IT49355/83A IT1212900B (it)	1983-11-17	1983-11-17	Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna

Publications (3)

Publication Number	Publication Date
DK524884D0 DK524884D0 (da)	1984-11-02
DK524884A true DK524884A (da)	1985-05-18
DK168271B1 DK168271B1 (da)	1994-03-07

Family

ID=11270453

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK524884A DK168271B1 (da)	1983-11-17	1984-11-02	Farmaceutiske præparater indeholdende phosphatidylserin og fremgangsmåde til fremstilling deraf

Country Status (25)

Country	Link
US (1)	US4595680A (da)
EP (1)	EP0148045B1 (da)
JP (1)	JPH0676334B2 (da)
KR (1)	KR870001330B1 (da)
AT (1)	ATE35415T1 (da)
AU (1)	AU572228B2 (da)
BE (1)	BE901074A (da)
CH (1)	CH661734A5 (da)
DE (1)	DE3472406D1 (da)
DK (1)	DK168271B1 (da)
ES (1)	ES8608528A1 (da)
FI (1)	FI79946C (da)
FR (1)	FR2555050B1 (da)
GR (1)	GR80951B (da)
HU (1)	HU193302B (da)
IE (1)	IE58130B1 (da)
IL (1)	IL73420A (da)
IN (1)	IN162717B (da)
IT (1)	IT1212900B (da)
LU (1)	LU85639A1 (da)
MX (1)	MX160792A (da)
NO (1)	NO164275C (da)
NZ (1)	NZ210091A (da)
PT (1)	PT79510B (da)
ZA (1)	ZA848776B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2471776A1 (fr) *	1979-12-21	1981-06-26	Oreal	Nouveaux agents cosmetiques a base de polymeres cationiques, compositions cosmetiques les contenant, et leur application
IT1213034B (it) *	1986-02-12	1989-12-07	Istituto Chemioterapico Di Lod	Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale.
US5314695A (en) *	1990-11-13	1994-05-24	Corvas International, Inc.	Tissue factor based prothrombin time reagent
FR2673512B1 (fr) *	1991-03-05	1993-08-20	Inst Rech Biolog Sa	Nouvelles compositions dietetiques a base de lipides complexes phosphores et leur utilisation dans les troubles du sommeil.
IT1247165B (it) *	1991-03-15	1994-12-12	Fidia Spa	Uso terapeutico della fosfatidilserina e derivati in patologie degenerative anche associate a disfunsioni immunitarie.
IT1248012B (it) *	1991-06-07	1995-01-05	Mediolanum Farmaceutici Spa	Impiego del fosfatidilinositolo per la terapia dei disturbi della depressione.
IT1260149B (it) *	1992-04-17	1996-03-28	Fidia Spa	Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali
GB9621293D0 (en) *	1996-10-11	1996-11-27	Scotia Holdings Plc	Formulations containing unsaturated fatty acids
CA2393595A1 (en) *	1999-12-10	2001-06-14	Gigi Chiu	Lipid carrier compositions with protected surface reactive functions
US7226916B1 (en) *	2000-05-08	2007-06-05	N.V. Nutricia	Preparation for the prevention and/or treatment of vascular disorders
CA2319928A1 (en)	2000-09-18	2002-03-18	Vasogen Ireland Limited	Apoptosis-mimicking synthetic entities and use thereof in medical treatments
TWI281407B (en) *	2000-09-18	2007-05-21	Vasogen Ireland Ltd	Apoptosis-mimicking synthetic entities and use thereof in medical treatment
US6676963B1 (en) *	2000-10-27	2004-01-13	Barnes-Jewish Hospital	Ligand-targeted emulsions carrying bioactive agents
US20040234544A1 (en) *	2001-08-09	2004-11-25	Ralf Jager	Formulation containing (lyso-)phosphatidylserine for the prevention and treatment of stress states in warm blooded animals
AU2003229693A1 (en) *	2002-04-19	2003-11-03	Biohurt Biograde Gmbh & Co. Kg	Matrix comprising a bioactive component containing phospholipid
US6878532B1 (en)	2003-04-28	2005-04-12	Sioux Biochemical, Inc.	Method of producing phosphatidylserine
CN1308334C (zh) *	2004-06-01	2007-04-04	山东师范大学	一种从动物脑提取磷脂酰丝氨酸的方法
IL182372A0 (en) *	2007-04-01	2008-01-20	Enzymotec Ltd	Compositions containing phosphatidylserine in treating diabetes-associated conditions
ITMI20121784A1 (it) *	2012-10-22	2014-04-23	Velleja Res Srl	Composizioni galattogeniche a base di fosfatidilserina
US20160317560A1 (en) *	2013-11-07	2016-11-03	The University Of North Carolina At Chapel Hill	Particles containing phospholipids or bioactive fatty acids and uses thereof
IT202100032252A1 (it) *	2021-12-22	2023-06-22	Fidia Farm Spa	Processo di estrazione e purificazione industriale di fosfolipidi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3156616A (en) *	1958-11-14	1964-11-10	Canada Majesty In Right Of	Composition and method for correcting foods and blood conditions having clot promoting characteristics
US3436413A (en) *	1965-12-21	1969-04-01	Canada Packers Ltd	Process for the isolation of phosphatidyl serine
FR5060M (da) *	1965-12-22	1967-05-08
US4078052A (en) *	1976-06-30	1978-03-07	The United States Of America As Represented By The Secretary Of Health, Education And Welfare	Large unilamellar vesicles (LUV) and method of preparing same
JPS55115824A (en) *	1979-02-28	1980-09-06	Nippon Shoji Kk	Remedy for clouding of consciousness and sensomobile disorder

1983
- 1983-11-17 IT IT49355/83A patent/IT1212900B/it active
1984
- 1984-04-12 US US06/599,341 patent/US4595680A/en not_active Expired - Fee Related
- 1984-10-30 IE IE278584A patent/IE58130B1/en not_active IP Right Cessation
- 1984-11-02 IN IN767/CAL/84A patent/IN162717B/en unknown
- 1984-11-02 DK DK524884A patent/DK168271B1/da not_active IP Right Cessation
- 1984-11-02 NZ NZ210091A patent/NZ210091A/xx unknown
- 1984-11-05 IL IL73420A patent/IL73420A/xx not_active IP Right Cessation
- 1984-11-09 ZA ZA848776A patent/ZA848776B/xx unknown
- 1984-11-12 ES ES537575A patent/ES8608528A1/es not_active Expired
- 1984-11-13 FR FR8417262A patent/FR2555050B1/fr not_active Expired
- 1984-11-13 LU LU85639A patent/LU85639A1/fr unknown
- 1984-11-14 FI FI844468A patent/FI79946C/fi not_active IP Right Cessation
- 1984-11-15 JP JP59242174A patent/JPH0676334B2/ja not_active Expired - Lifetime
- 1984-11-15 CH CH5471/84A patent/CH661734A5/fr not_active IP Right Cessation
- 1984-11-15 GR GR80951A patent/GR80951B/el unknown
- 1984-11-15 MX MX203403A patent/MX160792A/es unknown
- 1984-11-16 AU AU35630/84A patent/AU572228B2/en not_active Ceased
- 1984-11-16 BE BE0/214020A patent/BE901074A/nl not_active IP Right Cessation
- 1984-11-16 DE DE8484402340T patent/DE3472406D1/de not_active Expired
- 1984-11-16 PT PT79510A patent/PT79510B/pt not_active IP Right Cessation
- 1984-11-16 NO NO844585A patent/NO164275C/no unknown
- 1984-11-16 HU HU844269A patent/HU193302B/hu not_active IP Right Cessation
- 1984-11-16 EP EP84402340A patent/EP0148045B1/en not_active Expired
- 1984-11-16 AT AT84402340T patent/ATE35415T1/de not_active IP Right Cessation
- 1984-11-17 KR KR1019840007230A patent/KR870001330B1/ko not_active Expired

Also Published As

Publication number	Publication date
FI844468A0 (fi)	1984-11-14
HU193302B (en)	1987-09-28
IT1212900B (it)	1989-11-30
NZ210091A (en)	1988-06-30
ES8608528A1 (es)	1986-07-16
HUT35957A (en)	1985-08-28
IN162717B (da)	1988-07-02
EP0148045B1 (en)	1988-06-29
PT79510B (en)	1986-09-08
JPS60132921A (ja)	1985-07-16
NO164275B (no)	1990-06-11
CH661734A5 (fr)	1987-08-14
US4595680A (en)	1986-06-17
FI79946B (fi)	1989-12-29
IE842785L (en)	1985-05-17
BE901074A (nl)	1985-05-17
AU3563084A (en)	1985-05-30
ZA848776B (en)	1986-06-25
GR80951B (en)	1984-12-18
DK168271B1 (da)	1994-03-07
AU572228B2 (en)	1988-05-05
PT79510A (en)	1984-12-01
KR870001330B1 (ko)	1987-07-18
NO164275C (no)	1990-09-19
IE58130B1 (en)	1993-07-14
MX160792A (es)	1990-05-17
JPH0676334B2 (ja)	1994-09-28
FI844468L (fi)	1985-05-18
ES537575A0 (es)	1986-07-16
IL73420A0 (en)	1985-02-28
EP0148045A1 (en)	1985-07-10
DE3472406D1 (en)	1988-08-04
FI79946C (fi)	1990-04-10
ATE35415T1 (de)	1988-07-15
NO844585L (no)	1985-05-20
KR850003504A (ko)	1985-06-20
LU85639A1 (fr)	1985-06-04
FR2555050A1 (fr)	1985-05-24
IL73420A (en)	1988-06-30
DK524884D0 (da)	1984-11-02
FR2555050B1 (fr)	1986-12-26
IT8349355A0 (it)	1983-11-17

Legal Events

Date	Code	Title	Description
1994-03-07	B1	Patent granted (law 1993)
1995-07-24	PBP	Patent lapsed

Publication	Publication Date	Title
DK524884D0 (da)	1984-11-02	Farmaceutiske praeparater indeholdende phosphatidylserin og fremgangsmaade til fremstilling deraf
ES8700934A1 (es)	1986-11-16	Procedimiento para la obtencion de liposomas
ES8600060A1 (es)	1985-10-01	Procedimiento para preparar un medicamento envasado que contiene como sustancia activa un antagonista del calcio tal como nifedipina, verapamil diltiazem y otros.
ES542323A0 (es)	1985-12-16	Un procedimiento para la preparacion de derivados de la 2 pirimidinil-1-piperazina
MY103850A (en)	1993-09-30	Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them.
ATE26115T1 (de)	1987-04-15	Substituierte 8-phenylxanthine.
EP0652755A1 (en)	1995-05-17	THERAPEUTIC USE OF PHOSPHORYL-L-SERINE-N-ACYL-SPHINGOSINE.
ES8707111A1 (es)	1987-07-16	Procedimiento para obtencion de un preparado farmaceutico para tratamiento terapeutico de enfermedades reumaticas.
ATE59295T1 (de)	1991-01-15	Prazosin-pirbuterol-mischung zur bronchendilatation.
ES534859A0 (es)	1986-02-01	Procedimiento para la obtencion de derivados de 1-(4'-alquilsulfonilfenil)-2-amino-1,3-propandiol n-substituidos
BG90414A (bg)	1993-12-24	2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
ES8200871A1 (es)	1981-11-16	Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina
ATE24716T1 (de)	1987-01-15	Lenkotrien-antagonisten.
ATE32514T1 (de)	1988-03-15	3-(4'-aminobutylamino)-propylamino-bleomycinderivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.