DK525986A - Farmaceutisk pulver- eller tabletpraeparat indeholdende ibuprofen - Google Patents

Farmaceutisk pulver- eller tabletpraeparat indeholdende ibuprofen

Info

Publication number: DK525986A
Authority: DK; Denmark
Prior art keywords: pharmaceutically acceptable; pharmaceutical powder; ibup; trial; preparation containing
Prior art date: 1985-11-15

Application number

DK525986A

Other languages

English (en)

Other versions

DK525986D0 (da

DK166480B1 (da

Inventor

Karrar Ahmad Khan

John Francis Lampard

Original Assignee

Boots Co Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-15

Filing date

1986-11-04

Publication date

1987-05-16

1986-11-04 Application filed by Boots Co Plc filed Critical Boots Co Plc

1986-11-04 Publication of DK525986D0 publication Critical patent/DK525986D0/da

1987-05-16 Publication of DK525986A publication Critical patent/DK525986A/da

1993-06-01 Application granted granted Critical

1993-06-01 Publication of DK166480B1 publication Critical patent/DK166480B1/da

Links

239000000843 powder Substances 0.000 title abstract 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
150000001720 carbohydrates Chemical class 0.000 abstract 2
229920001477 hydrophilic polymer Polymers 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
239000001569 carbon dioxide Substances 0.000 abstract 1
229960001681 croscarmellose sodium Drugs 0.000 abstract 1
235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
239000008121 dextrose Substances 0.000 abstract 1
229960001680 ibuprofen Drugs 0.000 abstract 1
238000010348 incorporation Methods 0.000 abstract 1
239000008101 lactose Substances 0.000 abstract 1
235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
239000008108 microcrystalline cellulose Substances 0.000 abstract 1
229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
239000008180 pharmaceutical surfactant Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000600 sorbitol Substances 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1
239000007916 tablet composition Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Saccharide Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK525986A 1985-11-15 1986-11-04 Farmaceutisk pulver- eller tabletpraeparat indeholdende ibuprofen og en fremgangsmaade til fremstilling heraf DK166480B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858528195A GB8528195D0 (en)	1985-11-15	1985-11-15	Therapeutic compositions
GB8528195		1985-11-15

Publications (3)

Publication Number	Publication Date
DK525986D0 DK525986D0 (da)	1986-11-04
DK525986A true DK525986A (da)	1987-05-16
DK166480B1 DK166480B1 (da)	1993-06-01

Family

ID=10588293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK525986A DK166480B1 (da)	1985-11-15	1986-11-04	Farmaceutisk pulver- eller tabletpraeparat indeholdende ibuprofen og en fremgangsmaade til fremstilling heraf

Country Status (18)

Country	Link
US (1)	US4806358A (da)
EP (1)	EP0228164B1 (da)
JP (1)	JPS62135418A (da)
KR (1)	KR940002659B1 (da)
AT (1)	ATE70972T1 (da)
AU (1)	AU594265B2 (da)
CA (1)	CA1275933C (da)
DE (1)	DE3683270D1 (da)
DK (1)	DK166480B1 (da)
ES (1)	ES2027637T3 (da)
FI (1)	FI87523C (da)
GB (1)	GB8528195D0 (da)
GR (1)	GR3004023T3 (da)
IE (1)	IE59135B1 (da)
NO (1)	NO172423C (da)
NZ (1)	NZ218235A (da)
PT (1)	PT83750B (da)
ZA (1)	ZA868270B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1209667B (it) *	1985-11-12	1989-08-30	Zambon Spa	Composizione effeverscente adattivita' analgesica.
IT1197038B (it) *	1986-08-01	1988-11-25	Zambon Spa	Composizione farmaceutica ad attivita' analgesica
US4859704A (en) *	1987-10-15	1989-08-22	Oratech Pharmaceutical Development Corporation	Water soluble ibuprofen compositions and methods of making them
BR8907515A (pt) *	1988-06-28	1991-05-28	Du Pont	Formulacoes de pesticidas em comprimidos
CH677606A5 (da) *	1988-07-12	1991-06-14	Aesculapius Pharma Sa
GB8820327D0 (en) *	1988-08-26	1988-09-28	May & Baker Ltd	New compositions of matter
DE3838431A1 (de) *	1988-11-12	1990-05-17	Bayer Ag	Ibuprofen-brausezubereitungen
GB8909793D0 (en) *	1989-04-28	1989-06-14	Beecham Group Plc	Pharmaceutical formulation
US5262179A (en) *	1989-09-13	1993-11-16	Nicholas Kiwi Pty Ltd.	Non-effervescent ibuprofen compositions
GB8920693D0 (en) *	1989-09-13	1989-10-25	Nicholas Kiwi Pty Ltd	Non-effervescent ibuprofen compositions
US5064656A (en) *	1989-11-14	1991-11-12	Dr. Gergely & Co.	Uncoated pharmaceutical reaction tablet
US5009895A (en) *	1990-02-02	1991-04-23	Merck & Co., Inc.	Sustained release with high and low viscosity HPMC
IT1246350B (it) *	1990-07-11	1994-11-17	Eurand Int	Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
EP0584108B1 (en)	1991-05-13	2000-08-16	The Boots Company PLC	Pharmaceutical composition comprising ibuprofen salt
US5605930A (en) *	1991-10-21	1997-02-25	The United States Of America As Represented By The Department Of Health And Human Services	Compositions and methods for treating and preventing pathologies including cancer
JPH0672804A (ja) *	1992-04-08	1994-03-15	Sumitomo Chem Co Ltd	農薬錠剤
JPH05339150A (ja) *	1992-06-05	1993-12-21	Tokyo Tanabe Co Ltd	経口投与用ピリド［１，２−ａピリミジン誘導体の組成物
FR2698788B1 (fr) *	1992-12-09	1995-03-03	Union Pharma Scient Appl	Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
CH686865A5 (de) *	1994-06-15	1996-07-31	Gergely Gerhard	Pharmazeutische Zubereitung mit einem hydrophoben Wirkstoff und einem Brausesystem, sowie Verfahren zur Herstellung der Zubereitung.
US5738875A (en) *	1994-10-28	1998-04-14	R.P. Scherer Corporation	Process for preparing solid pharmaceutical dosage forms
DE19606151C2 (de) *	1996-02-20	1999-05-12	Losan Pharma Gmbh	Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
FR2753097A1 (fr) *	1996-09-11	1998-03-13	Barrau Francois	Gel aqueux ou hydroalcoolique extemporane a viscosite controlee
FR2776190B1 (fr) *	1998-03-20	2001-09-21	Asta Medica Ag	Composition effervescente stable comprenant au moins un compose anti-inflammatoire non steroidien, et procede d'obtention
DE19913606A1 (de) *	1999-03-25	2000-09-28	Basf Ag	Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen
AU777415B2 (en) *	1999-09-29	2004-10-14	R.P. Scherer Technologies, Inc.	Hydrolyzed cellulose granulations of salts of drugs
KR100429000B1 (ko) *	2001-08-14	2004-04-28	한국과학기술원	약물이 봉입된 다공성 생분해성 고분자 지지체의 제조방법
US7282217B1 (en)	2003-08-29	2007-10-16	Kv Pharmaceutical Company	Rapidly disintegrable tablets
US20050137262A1 (en) *	2003-12-22	2005-06-23	Hu Patrick C.	Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
PL204079B1 (pl) *	2004-08-12	2009-12-31	Inst Farmaceutyczny	Stały doustny preparat chlorowodorku tamsulozyny o przedłużonym uwalnianiu i sposób jego wytwarzania
CL2007002425A1 (es) *	2006-08-22	2008-06-27	Albermarle Corp	Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
JP4867668B2 (ja) *	2007-01-16	2012-02-01	株式会社村田製作所	絶縁型ｄｃ−ｄｃコンバータ
US20110086085A1 (en) *	2009-10-13	2011-04-14	Wenzel Scott W	Carbohydrate Entrapped Active Agent Delivery Composition and Articles Using the Same
EP2905020A1 (en) *	2014-02-05	2015-08-12	Sanovel Ilac Sanayi ve Ticaret A.S.	Effervescent formulations comprising ibuprofen and N-acetylcystein
ES2612238T3 (es)	2014-02-27	2017-05-12	Galenicum Health S.L.	Composiciones farmacéuticas estables
BR112017012927A2 (pt) *	2014-12-17	2018-03-13	Oreal	partícula compósita, processo cosmético e métodos para a preparação de uma partícula compósita
US20180078516A1 (en) *	2016-09-19	2018-03-22	Innovazone Labs LLC	Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration
JP7594929B2 (ja) *	2020-05-15	2024-12-05	花王株式会社	密封容器入り発泡性経口錠剤

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4538639B1 (da) *	1968-09-26	1970-12-05
DE2750207A1 (de) *	1977-05-09	1978-11-16	Walton J Smith	Gefriergetrocknete zusammensetzungen, insbesondere gefriergetrocknete pharmazeutische praeparate und verfahren zu deren herstellung
US4289751A (en) *	1979-06-29	1981-09-15	Merck & Co., Inc.	Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof
US4414198A (en) *	1982-04-23	1983-11-08	Joseph Michaelson	Rapidly disintegrable tablet composition and method
US4701470A (en) *	1982-12-06	1987-10-20	The Upjohn Company	Treatment of Type II Herpes virus with ibuprofen
JPH0647532B2 (ja) *	1983-08-31	1994-06-22	ジアツプジヨンカンパニ−	歯槽骨吸収の治療
US4678661A (en) *	1983-09-28	1987-07-07	Gerhard Gergely	Effervescent composition and method of making same
US4666716A (en) *	1984-09-04	1987-05-19	Richardson-Vicks Inc.	Antidiarrheal compositions and use thereof
GB2174004B (en) *	1985-04-23	1988-11-30	American Cyanamid Co	Pharmaceutical tablet preparations
US4687662A (en) *	1985-08-30	1987-08-18	Warner-Lambert Company	Therapeutic effervescent composition
IE59106B1 (en) *	1985-05-31	1994-01-12	Warner Lambert Co	A therapeutic effervescent composition and a method of preparing the same
DE3678644D1 (de) *	1985-08-16	1991-05-16	Procter & Gamble	Wirkstoffpartikel mit sowohl kontinuierlicher als auch schneller freisetzung.
IT1209667B (it) *	1985-11-12	1989-08-30	Zambon Spa	Composizione effeverscente adattivita' analgesica.

1985
- 1985-11-15 GB GB858528195A patent/GB8528195D0/en active Pending
1986
- 1986-10-22 IE IE278586A patent/IE59135B1/en not_active IP Right Cessation
- 1986-10-30 ZA ZA868270A patent/ZA868270B/xx unknown
- 1986-10-31 AT AT86308524T patent/ATE70972T1/de not_active IP Right Cessation
- 1986-10-31 ES ES198686308524T patent/ES2027637T3/es not_active Expired - Lifetime
- 1986-10-31 US US06/925,564 patent/US4806358A/en not_active Expired - Lifetime
- 1986-10-31 EP EP86308524A patent/EP0228164B1/en not_active Expired - Lifetime
- 1986-10-31 DE DE8686308524T patent/DE3683270D1/de not_active Expired - Lifetime
- 1986-11-04 DK DK525986A patent/DK166480B1/da not_active IP Right Cessation
- 1986-11-10 NZ NZ218235A patent/NZ218235A/xx unknown
- 1986-11-12 AU AU65091/86A patent/AU594265B2/en not_active Expired
- 1986-11-12 FI FI864605A patent/FI87523C/fi not_active IP Right Cessation
- 1986-11-14 CA CA000523016A patent/CA1275933C/en not_active Expired - Lifetime
- 1986-11-14 NO NO864547A patent/NO172423C/no not_active IP Right Cessation
- 1986-11-14 JP JP61271675A patent/JPS62135418A/ja active Granted
- 1986-11-14 PT PT83750A patent/PT83750B/pt not_active IP Right Cessation
- 1986-11-15 KR KR1019860009656A patent/KR940002659B1/ko not_active Expired - Fee Related
1992
- 1992-03-11 GR GR920400412T patent/GR3004023T3/el unknown

Also Published As

Publication number	Publication date
KR870004701A (ko)	1987-06-01
GR3004023T3 (da)	1993-03-31
DK525986D0 (da)	1986-11-04
NO864547D0 (no)	1986-11-14
IE862785L (en)	1987-05-15
NO172423B (no)	1993-04-13
EP0228164A2 (en)	1987-07-08
KR940002659B1 (ko)	1994-03-28
DE3683270D1 (de)	1992-02-13
CA1275933C (en)	1990-11-06
AU594265B2 (en)	1990-03-01
IE59135B1 (en)	1994-01-12
DK166480B1 (da)	1993-06-01
JPH0415204B2 (da)	1992-03-17
JPS62135418A (ja)	1987-06-18
EP0228164A3 (en)	1987-09-16
AU6509186A (en)	1987-05-21
ES2027637T3 (es)	1992-06-16
US4806358A (en)	1989-02-21
NO172423C (no)	1993-07-21
EP0228164B1 (en)	1992-01-02
PT83750A (en)	1986-12-01
ZA868270B (en)	1987-06-24
NZ218235A (en)	1989-06-28
FI87523B (fi)	1992-10-15
FI87523C (fi)	1993-01-25
PT83750B (pt)	1988-08-17
ATE70972T1 (de)	1992-01-15
FI864605A0 (fi)	1986-11-12
FI864605L (fi)	1987-05-16
GB8528195D0 (en)	1985-12-18
NO864547L (no)	1987-05-18

Legal Events

Date	Code	Title	Description
2006-11-27	PUP	Patent expired

Publication	Publication Date	Title
DK525986D0 (da)	1986-11-04	Farmaceutisk pulver- eller tabletpraeparat indeholdende ibuprofen
MX10086A (es)	1993-12-01	Un sistema para la administracion de substancias activas no solubles en agua y procedimiento para su preparacion.
ATE100708T1 (de)	1994-02-15	Unbeschichtete pharmazeutische reaktionstablette.
IL71506A (en)	1987-09-16	Rapid dissolving,uniform pharmaceutical compositions of low water solubility drugs and their preparation
IL80149A (en)	1990-11-29	Pharmaceutical compositions containing toluidide derivatives against graft-versus-host diseases and autoimmune diseases
EP0890359A4 (da)	1999-01-13
NO880904D0 (no)	1988-03-01	Farmasoeytisk tablett, farmasoeytisk granulat og fremgangsmaate for deres fremstilling.
IL89702A0 (en)	1989-09-28	Water soluble ibuprofen compositions,processes for the preparation thereof and pharmaceutical compositions containing the same
AU7451198A (en)	1998-12-30	Solid pharmaceutical preparation
EP0348808A3 (de)	1991-04-17	Neue Arzneimittelformulierung sowie Verfahren zu deren Herstellung
MY104013A (en)	1993-10-30	Drug adsorbates.
ES550807A0 (es)	1987-05-16	Un procedimiento para la produccion de un preparado farmaceutico de liberacion lenta y controlada.
NO900276L (no)	1990-07-23	Nye benzopyranderivater, deres fremstilling og anvendelsei farmasoeytiske preparater.
AU1729397A (en)	1997-08-28	Process to prepare soluble delivery systems using volatile salts
MY101593A (en)	1991-12-17	Sustained release preparation.
DE69620606D1 (de)	2002-05-16	Feste oral anzuwendende arzeneiform
AU1531199A (en)	1999-07-05	Pharmaceutical suspension tablet compositions
IT8820073A0 (it)	1988-04-01	Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
DK342989D0 (da)	1989-07-11	Betaendelseshaemmende middel
SE8901003L (sv)	1989-09-26	Snabbloesliga preparat
GB1327560A (en)	1973-08-22	Effervescent pharmaceutical preparations
Unit et al.	1989	The International pharmacopoeia= Pharmacopoea internationalis: monographs for pharmaceutical dosage forms
RU93049678A (ru)	1997-03-10	Устойчивый водорастворимый ветеринарный препарат и способ его получения
NO964775L (no)	1993-01-27	Fast farmasöytisk adenosinholdig preparat
ZA896524B (en)	1991-04-24	Substituted 4-azatricyclo(22.3.1.0 4,9)octacos-18-ene derivatives,their preparation and pharmaceutical compositions containing them