DK526077A - Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler - Google Patents

Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Info

Publication number
DK526077A
DK526077A DK526077A DK526077A DK526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A
Authority
DK
Denmark
Prior art keywords
organts
callicrain
antiphlogical
bpti
beef
Prior art date
Application number
DK526077A
Other languages
English (en)
Inventor
E Schnabel
G Reinhardt
H D Schlumberger
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK526077A publication Critical patent/DK526077A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK526077A 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler DK526077A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762654124 DE2654124A1 (de) 1976-11-29 1976-11-29 Derivate des trypsin-kallikrein-inhibitors aus rinderorganen (bpti) mit proteasenhemmwirkung und antiphlogistischer wirkung, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK526077A true DK526077A (da) 1978-05-30

Family

ID=5994225

Family Applications (1)

Application Number Title Priority Date Filing Date
DK526077A DK526077A (da) 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Country Status (10)

Country Link
US (1) US4153687A (da)
JP (1) JPS5368701A (da)
BE (1) BE861267A (da)
DE (1) DE2654124A1 (da)
DK (1) DK526077A (da)
ES (1) ES464571A1 (da)
FR (1) FR2373516A1 (da)
GB (1) GB1557599A (da)
NL (1) NL7713091A (da)
SE (1) SE7713436L (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
RU2054180C1 (ru) * 1991-08-21 1996-02-10 Жирнов Олег Петрович (н/п) Способ лечения вирусных респираторных инфекций
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
DE69533472T2 (de) * 1994-01-11 2006-01-12 Dyax Corp., Cambridge Kallikreinhemmende "kunitz-domäne"-proteine und derivaten davon
ATE529444T1 (de) * 1994-01-11 2011-11-15 Dyax Corp Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
DK2311432T3 (da) 2002-06-07 2015-02-02 Dyax Corp Modificerede Kunitz-domæne-polypeptider og deres anvendelse til reduktion af iskæmi eller indtræden af en systemisk inflammatorisk reaktion i forbindelse med en kirurgisk procedure
TR201900937T4 (tr) 2002-08-28 2019-02-21 Dyax Corp Organların ve dokuların muhafaza edilmesine yönelik yöntem.
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
EP2001500A4 (en) * 2006-03-10 2010-07-28 Dyax Corp FORMULATIONS FOR ECALLANTIDE
US8637454B2 (en) * 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
ES2688093T3 (es) * 2010-01-06 2018-10-30 Dyax Corp. Proteínas de unión a calicreína plasmática
IL269565B2 (en) 2011-01-06 2024-06-01 Dyax Corp Plasma kallikrein binding proteins
US9315811B2 (en) 2011-06-10 2016-04-19 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (KLKB1) expression
AU2012275096B2 (en) 2011-06-29 2016-02-04 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (KLKB1) expression
KR102365486B1 (ko) 2013-08-28 2022-02-18 아이오니스 파마수티컬즈, 인코포레이티드 프리칼리크레인 (pkk) 발현의 조절
EP3122782A4 (en) 2014-03-27 2017-09-13 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
JP6665111B2 (ja) 2014-05-01 2020-03-13 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Ｐｋｋ発現を調節するための組成物及び方法
BR112018011622A2 (pt) 2015-12-11 2018-11-27 Dyax Corp método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae
CA3167336A1 (en) 2020-01-13 2021-07-22 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack

Also Published As

Publication number Publication date
FR2373516B1 (da) 1980-06-13
ES464571A1 (es) 1978-09-01
US4153687A (en) 1979-05-08
DE2654124A1 (de) 1978-06-01
NL7713091A (nl) 1978-05-31
FR2373516A1 (fr) 1978-07-07
JPS5368701A (en) 1978-06-19
BE861267A (fr) 1978-05-29
GB1557599A (en) 1979-12-12
SE7713436L (sv) 1978-05-30

Similar Documents

Publication Publication Date Title
FI773900A7 (fi) Gasseparering
DK81578A (da) Kassette til affyring af afvaergeprojektiler
DK470277A (da) Liprosomer indeholdende heparin og fremgangsmaade til deres fremstilling
SE433106B (sv) Gaskompressor
DK208378A (da) Fremgangsmaade til desodorisering af ajle og til fjernelse af skadelige luftarter
DK188077A (da) Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse
DK252680A (da) Hidtil ukendte (ergolin-yl)-n!,n!-diethylurinstofderivater fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel
DK352377A (da) Azolyl-carboxylsyrederivater fremgangsmade til deres fremstilling og deres anvendelse som fungicider
DK403577A (da) Piperazinylpyridiner til anvendelse som anoreziske midler og fremgangsmaade til fremstilling af disse forbindelser
AT370918B (de) Gasentladungslaser
DK496977A (da) Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
DK538677A (da) Isoxazolderivater fremgangsmaade til deres fremstilling og midler indeholdende disse forbindelser
DK438977A (da) Fremgangsmaade ved fraktionering af en gasblanding
DK82177A (da) Fremgangsmade til fremstilling af aminoglycosidderivater mellemprodukter til anvendelse ved denne fremgangsmade og fremgangsmade til deres fresmtilling
DK300977A (da) Fremgangsmade til fremstilling af (3-amino-5-substitueret -6-fluorpyrazinoyl- eller pyrazamido) guanidiner og derivater deraf
DK205377A (da) Prostaglandin-derivater deres fremstilling og anvendelse
DK154273C (da) Vaerktoej til montering af spaendebaand og lignende
DK577377A (da) Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere
DK245077A (da) Fremgangsmade til fremstilling af benzamidderivater
DK15077A (da) Fremgangsmade til kvantitativ bestemmelse af antithrombin iii
DK409277A (da) Pentapeptider og fremgangsmaade til deres fremstilling
DK118177A (da) Fremgangsmade til fremstilling af isobutyramidderivater
DK255577A (da) Fremgangsmade til fremstilling af 3,4-dihydro-2-methyl-4-oxo-2h-1,2-benzothiazin-3-carboxylsyre1,1-dioxid og dets anvendelse som mellemprodukt
DK31977A (da) Fremgangsmade til fremstilling af chromanderivater
DK5777A (da) Acylamino-(alkyl)-benzenderivater samt deres fremstilling og anvendelse