DK188077A - Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse - Google Patents

Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse

Info

Publication number
DK188077A
DK188077A DK188077A DK188077A DK188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A
Authority
DK
Denmark
Prior art keywords
callicraine
preparation
trypsin inhibitor
desamino
derivatives
Prior art date
Application number
DK188077A
Other languages
English (en)
Inventor
E Schnabel
H D Schlumberger
G Reinhardt
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK188077A publication Critical patent/DK188077A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK188077A 1976-04-30 1977-04-29 Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse DK188077A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619246 DE2619246A1 (de) 1976-04-30 1976-04-30 Desamino-derivate des kallikrein- trypsin-inhibitors, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK188077A true DK188077A (da) 1977-10-31

Family

ID=5976820

Family Applications (1)

Application Number Title Priority Date Filing Date
DK188077A DK188077A (da) 1976-04-30 1977-04-29 Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse

Country Status (11)

Country Link
US (1) US4118481A (da)
JP (1) JPS52134009A (da)
AT (1) AT361118B (da)
BE (1) BE854102A (da)
CH (1) CH635514A5 (da)
DE (1) DE2619246A1 (da)
DK (1) DK188077A (da)
FR (1) FR2349598A1 (da)
GB (1) GB1533358A (da)
NL (1) NL7704690A (da)
SE (1) SE442301B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
DE69533472T2 (de) * 1994-01-11 2006-01-12 Dyax Corp., Cambridge Kallikreinhemmende "kunitz-domäne"-proteine und derivaten davon
ATE529444T1 (de) * 1994-01-11 2011-11-15 Dyax Corp Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
DK2311432T3 (da) 2002-06-07 2015-02-02 Dyax Corp Modificerede Kunitz-domæne-polypeptider og deres anvendelse til reduktion af iskæmi eller indtræden af en systemisk inflammatorisk reaktion i forbindelse med en kirurgisk procedure
TR201900937T4 (tr) 2002-08-28 2019-02-21 Dyax Corp Organların ve dokuların muhafaza edilmesine yönelik yöntem.
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
EP2001500A4 (en) * 2006-03-10 2010-07-28 Dyax Corp FORMULATIONS FOR ECALLANTIDE
WO2009026334A2 (en) * 2007-08-21 2009-02-26 Genzyme Corporation Treatment with kallikrein inhibitors
CA2695012A1 (en) * 2007-08-23 2009-02-26 Genzyme Corporation Treatment with kallikrein inhibitors
US8637454B2 (en) * 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
ES2688093T3 (es) * 2010-01-06 2018-10-30 Dyax Corp. Proteínas de unión a calicreína plasmática
IL269565B2 (en) 2011-01-06 2024-06-01 Dyax Corp Plasma kallikrein binding proteins
EP3122782A4 (en) 2014-03-27 2017-09-13 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
BR112018011622A2 (pt) 2015-12-11 2018-11-27 Dyax Corp método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae
CA3167336A1 (en) 2020-01-13 2021-07-22 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack

Also Published As

Publication number Publication date
SE442301B (sv) 1985-12-16
FR2349598B1 (da) 1980-02-22
SE7704928L (sv) 1977-10-31
CH635514A5 (de) 1983-04-15
FR2349598A1 (fr) 1977-11-25
ATA305477A (de) 1980-07-15
AT361118B (de) 1981-02-25
BE854102A (fr) 1977-10-31
US4118481A (en) 1978-10-03
GB1533358A (en) 1978-11-22
NL7704690A (nl) 1977-11-01
DE2619246A1 (de) 1977-11-10
JPS52134009A (en) 1977-11-09

Similar Documents

Publication Publication Date Title
DK242578A (da) Tetrahydrofuranderivater deres fremstilling og anvendelse
DK59677A (da) Fremgangsmade til fremstilling af prolinderivater og dermed beslegtede forbindelser
DK143378A (da) Cephemderivater deres fremstilling og anvndelse
DK162878A (da) Cephemderivater deres fremstilling og anvendelse
DK8277A (da) Fremstilling af cement og udnyttelse af affald
DK526077A (da) Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler
DK430577A (da) Heterocycliske forbindelser deres fremstilling og anvendelse
DK578978A (da) Cephalosporinderivater deres fremstilling og anvendelse
DK538277A (da) Derivater af thiazolidinacarboxylsyrer og dermed beslaegtede syrer
DK490077A (da) Fremgangsmaade til fremstilling af hydraulisk cement og cementforstadier
DK108078A (da) Benzodiazepinderivater deres fremstilling og anvendelse
DK278178A (da) Sulfamoylarylketoner deres fremstilling og anvendelse
DK205377A (da) Prostaglandin-derivater deres fremstilling og anvendelse
DK534277A (da) Faststofdispersioner deres fremstilling og anvendelse
DK191877A (da) Derivater af n-phosphonomethylglycin
DK25277A (da) 17alfa-estere af gestagener samt deres fremstilling og anvendelse
DK271178A (da) Blandinger af azoforbindelser deres fremstilling og anvendelse
DK244775A (da) Derivater af 2-amino-1,3-thiazin, deres fremstilling og anvendelse
DK386677A (da) Methioninencephalinderivater deres fremstilling og anvendelsesamt mellemprodukter til fremstillingen
DK463876A (da) Fremgangsmade til fremstilling af gipsskum og deraf bestaende bygningselementer
DK5777A (da) Acylamino-(alkyl)-benzenderivater samt deres fremstilling og anvendelse
NO771398L (no) Fenylpiperaziner og fremgangsm}te til deres fremstilling
DK503077A (da) Disaccaridderivat af antracykliner og fremgangsmaade til fremstilling deraf
DK254077A (da) Benzylcyanocetaler deres fremstilling og anvendelse
DK581181A (da) Thiazolinderivater deres fremstilling og anvendelse

Legal Events

Date Code Title Description
ATS Application withdrawn