DK528989A - Vaevsplasminogenaktivator-(t-pa)-muteiner og fremgangsmaade til fremstilling deraf - Google Patents
Vaevsplasminogenaktivator-(t-pa)-muteiner og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK528989A DK528989A DK528989A DK528989A DK528989A DK 528989 A DK528989 A DK 528989A DK 528989 A DK528989 A DK 528989A DK 528989 A DK528989 A DK 528989A DK 528989 A DK528989 A DK 528989A
- Authority
- DK
- Denmark
- Prior art keywords
- muteines
- procedures
- producing
- tissue plasma
- minogen activator
- Prior art date
Links
- 239000012190 activator Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3836200A DE3836200A1 (de) | 1988-10-24 | 1988-10-24 | Domaenenduplikations-muteine des gewebsplasminogen-aktivators (t-pa) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK528989D0 DK528989D0 (da) | 1989-10-24 |
| DK528989A true DK528989A (da) | 1990-04-25 |
Family
ID=6365810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK528989A DK528989A (da) | 1988-10-24 | 1989-10-24 | Vaevsplasminogenaktivator-(t-pa)-muteiner og fremgangsmaade til fremstilling deraf |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0366091A3 (da) |
| JP (1) | JPH02215384A (da) |
| AU (1) | AU609337B2 (da) |
| DE (1) | DE3836200A1 (da) |
| DK (1) | DK528989A (da) |
| IL (1) | IL92015A0 (da) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63501841A (ja) * | 1985-12-20 | 1988-07-28 | ジ・アップジョン・カンパニ− | 組織プラスミノ−ゲンアクチベ−タ−（ｔｐａ）同族体 |
| AU600463B2 (en) * | 1985-12-20 | 1990-08-16 | Pharmacia & Upjohn Company | Tissue plasminogen activator (tpa) analogs |
| DE3682891D1 (de) * | 1986-02-17 | 1992-01-23 | Stichting Centraal Lab | Gewebeplasminogen-aktivator-mutant, dafuer kodierende rekombinante genetische information und verfahren zur herstellung dieser mutanten, deren verwendung und pharmazeutische zusammensetzungen. |
| GB8608020D0 (en) * | 1986-04-02 | 1986-05-08 | Beecham Group Plc | Compounds |
| ATE110772T1 (de) * | 1987-06-04 | 1994-09-15 | Zymogenetics Inc | Mutierter t-pa mit kringle-ersatz. |
-
1988
- 1988-10-24 DE DE3836200A patent/DE3836200A1/de not_active Withdrawn
-
1989
- 1989-10-17 IL IL92015A patent/IL92015A0/xx unknown
- 1989-10-23 AU AU43657/89A patent/AU609337B2/en not_active Ceased
- 1989-10-24 EP EP19890119757 patent/EP0366091A3/de not_active Withdrawn
- 1989-10-24 JP JP1275117A patent/JPH02215384A/ja active Pending
- 1989-10-24 DK DK528989A patent/DK528989A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4365789A (en) | 1990-04-26 |
| DE3836200A1 (de) | 1990-04-26 |
| IL92015A0 (en) | 1990-07-12 |
| AU609337B2 (en) | 1991-04-26 |
| EP0366091A3 (de) | 1990-09-05 |
| JPH02215384A (ja) | 1990-08-28 |
| DK528989D0 (da) | 1989-10-24 |
| EP0366091A2 (de) | 1990-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |