DK542989A - Praeparat til bekaempelse af ocular hypertension - Google Patents
Praeparat til bekaempelse af ocular hypertensionInfo
- Publication number
- DK542989A DK542989A DK542989A DK542989A DK542989A DK 542989 A DK542989 A DK 542989A DK 542989 A DK542989 A DK 542989A DK 542989 A DK542989 A DK 542989A DK 542989 A DK542989 A DK 542989A
- Authority
- DK
- Denmark
- Prior art keywords
- ocular hypertension
- fighting
- preparation
- disclosed
- steroids
- Prior art date
Links
- 206010030043 Ocular hypertension Diseases 0.000 title abstract 4
- 150000003431 steroids Chemical class 0.000 abstract 2
- 206010030348 Open-Angle Glaucoma Diseases 0.000 abstract 1
- 230000000964 angiostatic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 201000006366 primary open angle glaucoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/264,918 US4876250A (en) | 1988-10-31 | 1988-10-31 | Methods for controlling ocular hypertension with angiostatic steroids |
| US26491888 | 1988-10-31 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK542989D0 DK542989D0 (da) | 1989-10-31 |
| DK542989A true DK542989A (da) | 1990-05-01 |
| DK172058B1 DK172058B1 (da) | 1997-10-06 |
Family
ID=23008183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK542989A DK172058B1 (da) | 1988-10-31 | 1989-10-31 | Præparat til regulering af okular hypertension i forbindelse med primært åbenvinklet glaukom samt anvendelse af angiostatiske steroider til fremstilling af sådanne præparater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4876250A (da) |
| EP (1) | EP0371617B1 (da) |
| JP (1) | JP3049504B2 (da) |
| KR (1) | KR900005984A (da) |
| AT (1) | ATE106731T1 (da) |
| AU (1) | AU628874B2 (da) |
| CA (1) | CA2001936C (da) |
| DE (1) | DE68915958T2 (da) |
| DK (1) | DK172058B1 (da) |
| NZ (1) | NZ231086A (da) |
| PT (1) | PT92123B (da) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5407926A (en) * | 1987-12-29 | 1995-04-18 | Alcon Laboratories, Inc. | Ophthalmic composition |
| US5990099A (en) * | 1988-10-31 | 1999-11-23 | Alcon Laboratories, Inc. | Angiostatic agents and methods and compositions for controlling ocular hypertension |
| US5135920A (en) * | 1988-11-16 | 1992-08-04 | Takeda Chemical Industries, Ltd. | Angiostatic agents |
| US5256408A (en) * | 1990-06-12 | 1993-10-26 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5209926A (en) * | 1990-06-12 | 1993-05-11 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5252319A (en) * | 1990-06-12 | 1993-10-12 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| WO1992016235A1 (en) * | 1991-03-21 | 1992-10-01 | Mount Sinai School Of Medicine Of The City University Of New York | Compositions and methods of treatment of a variety of disorders utilizing etianate and agonists thereof |
| US5239094A (en) * | 1991-04-12 | 1993-08-24 | Brigham And Women's Hospital | Tetrahydro-S-21-Br |
| ATE185071T1 (de) * | 1991-06-18 | 1999-10-15 | Theramex | Steroide enthaltende zusammensetzungen zur anwendung am auge und ihre verwendung zur behandlung des glaukoms |
| US5770592A (en) * | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
| DK0614463T3 (da) * | 1991-11-22 | 2003-03-31 | Alcon Lab Inc | Angiostatiske steroider |
| US5679666A (en) * | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
| US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
| US5646136A (en) * | 1994-01-04 | 1997-07-08 | Duke University | Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids |
| US5521168A (en) * | 1994-10-13 | 1996-05-28 | Alcon Laboratories, Inc. | Estrogen metabolites for lowering intraocular pressure |
| US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
| US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
| US6172054B1 (en) | 1995-06-15 | 2001-01-09 | Alcon Laboratories, Inc. | Combination therapy for lowering and controlling intraocular pressure |
| CA2237898A1 (en) * | 1995-11-17 | 1997-05-29 | Louis Desantis Jr. | Combination therapy for treating glaucoma |
| US6011023A (en) * | 1997-08-27 | 2000-01-04 | Alcon Laboratories, Inc. | Angiostatic steroids |
| WO2001041781A2 (en) * | 1999-12-09 | 2001-06-14 | Alcon Universal Ltd. | Id protein inhibitors for treating ocular diseases |
| US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
| US8679089B2 (en) | 2001-05-21 | 2014-03-25 | Michael S. Berlin | Glaucoma surgery methods and systems |
| ATE377404T1 (de) | 2000-05-19 | 2007-11-15 | Michael S Berlin | Laserapplikationssystem und methode zur verwendung im auge |
| WO2002040030A1 (en) * | 2000-11-16 | 2002-05-23 | Alcon Manufacturing, Ltd. | Combination therapy for lowering and controlling intraocular pressure |
| CN103143022A (zh) | 2002-07-30 | 2013-06-12 | 奥默罗斯公司 | 眼科冲洗液及方法 |
| ES2244361T1 (es) * | 2002-08-05 | 2005-12-16 | Alcon, Inc. | Uso del acetato de anecortave para la proteccion de la agudeza visual en pacientes con degeneracion macular asociada a la edad. |
| RU2006113593A (ru) * | 2003-09-23 | 2006-08-27 | Алькон, Инк. (Ch) | Препаративные формы триамцинолона ацетонида и анекортава ацетата для инъекций |
| US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
| US20170360609A9 (en) | 2007-09-24 | 2017-12-21 | Ivantis, Inc. | Methods and devices for increasing aqueous humor outflow |
| EP2259833A1 (en) | 2008-03-05 | 2010-12-15 | Ivantis, INC. | Methods and apparatus for treating glaucoma |
| HUE027463T2 (en) | 2008-05-28 | 2016-09-28 | Reveragen Biopharma Inc | Non-hormonal steroid modulators of nf-kb for treatment of disease |
| AU2010271218B2 (en) | 2009-07-09 | 2017-02-02 | Alcon Inc. | Ocular implants and methods for delivering ocular implants into the eye |
| WO2011006078A1 (en) | 2009-07-09 | 2011-01-13 | Ivantis, Inc. | Single operator device for delivering an ocular implant |
| WO2011106435A2 (en) | 2010-02-23 | 2011-09-01 | Powervision, Inc. | Fluid for accommodating intraocular lenses |
| US9198921B2 (en) | 2010-04-05 | 2015-12-01 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
| US20120283557A1 (en) | 2011-05-05 | 2012-11-08 | Berlin Michael S | Methods and Apparatuses for the Treatment of Glaucoma using visible and infrared ultrashort laser pulses |
| US8657776B2 (en) | 2011-06-14 | 2014-02-25 | Ivantis, Inc. | Ocular implants for delivery into the eye |
| US8663150B2 (en) | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
| US9358156B2 (en) | 2012-04-18 | 2016-06-07 | Invantis, Inc. | Ocular implants for delivery into an anterior chamber of the eye |
| AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| US10617558B2 (en) | 2012-11-28 | 2020-04-14 | Ivantis, Inc. | Apparatus for delivering ocular implants into an anterior chamber of the eye |
| EP3785668A1 (en) | 2013-03-15 | 2021-03-03 | Alcon Inc. | Intraocular lens storage and loading devices and methods of use |
| US10709547B2 (en) | 2014-07-14 | 2020-07-14 | Ivantis, Inc. | Ocular implant delivery system and method |
| TWI705812B (zh) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| ES2962463T3 (es) | 2015-06-10 | 2024-03-19 | Alcon Inc | Materiales y componentes de lentes intraoculares |
| US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
| JP6837475B2 (ja) | 2015-08-14 | 2021-03-03 | イバンティス インコーポレイテッド | 圧力センサを備えた眼用インプラントおよび送達システム |
| US11938058B2 (en) | 2015-12-15 | 2024-03-26 | Alcon Inc. | Ocular implant and delivery system |
| EP4371535A3 (en) | 2018-02-22 | 2024-08-14 | Alcon Inc. | Ocular implant |
| US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
| AU2022205382B2 (en) | 2021-01-11 | 2026-02-19 | Alcon Inc. | Systems and methods for viscoelastic delivery |
| AU2024309881A1 (en) | 2023-06-30 | 2025-11-20 | Alcon Inc. | System and methods for compensating for intraocular lens tilt |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617299A (en) * | 1983-12-19 | 1986-10-14 | Knepper Paul A | Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension |
| EP0197158B1 (en) * | 1984-10-05 | 1993-01-13 | Olympus Optical Co., Ltd. | Compound magnetic head |
| ATE66002T1 (de) * | 1985-10-23 | 1991-08-15 | Upjohn Co | Angiostatische steroide. |
| US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
| US4863912A (en) * | 1986-05-19 | 1989-09-05 | New York Medical College | Use of tetrahydrocortisol in glaucoma therapy |
| US4945089A (en) * | 1987-12-29 | 1990-07-31 | Alcon Laboratories, Inc. | Use of tetrahydrocortexolone to prevent elevations in intraocular pressure caused by corticosteroids |
-
1988
- 1988-10-31 US US07/264,918 patent/US4876250A/en not_active Expired - Lifetime
-
1989
- 1989-10-19 NZ NZ231086A patent/NZ231086A/en unknown
- 1989-10-24 AU AU43702/89A patent/AU628874B2/en not_active Expired
- 1989-10-27 PT PT92123A patent/PT92123B/pt not_active IP Right Cessation
- 1989-10-31 DE DE68915958T patent/DE68915958T2/de not_active Expired - Lifetime
- 1989-10-31 DK DK542989A patent/DK172058B1/da not_active IP Right Cessation
- 1989-10-31 AT AT89311238T patent/ATE106731T1/de not_active IP Right Cessation
- 1989-10-31 JP JP1285990A patent/JP3049504B2/ja not_active Expired - Lifetime
- 1989-10-31 KR KR1019890015694A patent/KR900005984A/ko not_active Withdrawn
- 1989-10-31 EP EP89311238A patent/EP0371617B1/en not_active Expired - Lifetime
- 1989-10-31 CA CA002001936A patent/CA2001936C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68915958D1 (de) | 1994-07-14 |
| JP3049504B2 (ja) | 2000-06-05 |
| JPH02196722A (ja) | 1990-08-03 |
| CA2001936A1 (en) | 1990-04-30 |
| EP0371617A3 (en) | 1992-01-22 |
| US4876250A (en) | 1989-10-24 |
| AU628874B2 (en) | 1992-09-24 |
| EP0371617A2 (en) | 1990-06-06 |
| AU4370289A (en) | 1990-05-03 |
| NZ231086A (en) | 1991-07-26 |
| PT92123B (pt) | 1995-06-30 |
| DK172058B1 (da) | 1997-10-06 |
| DE68915958T2 (de) | 1994-09-22 |
| PT92123A (pt) | 1990-05-31 |
| DK542989D0 (da) | 1989-10-31 |
| ATE106731T1 (de) | 1994-06-15 |
| KR900005984A (ko) | 1990-05-07 |
| CA2001936C (en) | 2000-04-25 |
| EP0371617B1 (en) | 1994-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |