DK551689A - Optisk aktive benzoxaziner og benzotriaziner samt fremgangsmaade til stereospecifik fremstilling af saadanne forbindelser - Google Patents

Optisk aktive benzoxaziner og benzotriaziner samt fremgangsmaade til stereospecifik fremstilling af saadanne forbindelser

Info

Publication number
DK551689A
DK551689A DK551689A DK551689A DK551689A DK 551689 A DK551689 A DK 551689A DK 551689 A DK551689 A DK 551689A DK 551689 A DK551689 A DK 551689A DK 551689 A DK551689 A DK 551689A
Authority
DK
Denmark
Prior art keywords
benzotriazines
benzoxazines
procedures
compounds
optically active
Prior art date
Application number
DK551689A
Other languages
English (en)
Other versions
DK551689D0 (da
Inventor
Willem Johan Van Zoest
Arthur Friedrich Marx
Hein Simon Koger
Johannes Booy
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of DK551689D0 publication Critical patent/DK551689D0/da
Publication of DK551689A publication Critical patent/DK551689A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK551689A 1988-11-07 1989-11-06 Optisk aktive benzoxaziner og benzotriaziner samt fremgangsmaade til stereospecifik fremstilling af saadanne forbindelser DK551689A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88202484 1988-11-07
EP89200368 1989-02-14

Publications (2)

Publication Number Publication Date
DK551689D0 DK551689D0 (da) 1989-11-06
DK551689A true DK551689A (da) 1990-05-08

Family

ID=26115413

Family Applications (1)

Application Number Title Priority Date Filing Date
DK551689A DK551689A (da) 1988-11-07 1989-11-06 Optisk aktive benzoxaziner og benzotriaziner samt fremgangsmaade til stereospecifik fremstilling af saadanne forbindelser

Country Status (11)

Country Link
EP (1) EP0368410A3 (da)
JP (1) JPH02178287A (da)
CN (1) CN1042538A (da)
AU (1) AU4376589A (da)
CA (1) CA2002395A1 (da)
DK (1) DK551689A (da)
FI (1) FI895268A7 (da)
HU (1) HUT54128A (da)
IL (1) IL92217A0 (da)
NO (1) NO894399L (da)
PT (1) PT92219A (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057305A (en) * 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
KR0134534B1 (ko) * 1995-03-20 1998-04-21 김은영 (-)3(s)-메틸벤즈옥사진 유도체의 제조방법
WO2001081286A1 (en) * 2000-04-21 2001-11-01 Rhodia/Chirex, Inc. Process for preparation of r-1-(aryloxy)propan-2-ol
JP4721541B2 (ja) * 2001-03-28 2011-07-13 第一三共株式会社 光学活性プロポキシニトロベンゼン誘導体の製造方法
US7629458B2 (en) * 2001-10-03 2009-12-08 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and hemihydrate thereof
CN101659669B (zh) * 2009-09-04 2011-07-20 诚达药业股份有限公司 左旋氧氟沙星的制备方法
CN101768167B (zh) * 2010-01-15 2012-07-04 浙江东亚药业有限公司 左氧氟沙星的缩哌合成方法
CN102408390B (zh) * 2011-12-11 2013-08-07 湖南科技大学 具有杀菌活性的n-取代-3,4-二氢-1,4-苯并恶嗪类化合物
CN112062687B (zh) * 2020-09-02 2023-11-21 上海信谊万象药业股份有限公司 一种盐酸阿扎司琼中间体3-氨基-5-氯-2-羟基苯甲酸甲酯的合成方法
CN114133362B (zh) * 2021-12-07 2025-11-07 北京中医药大学 一种合成[1,2]噻嗪类衍生物的绿色方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO166131C (no) * 1985-06-20 1991-06-05 Daiichi Seiyaku Co Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.
US4777253A (en) * 1986-04-25 1988-10-11 Abbott Laboratories Process for preparation of racemate and optically active ofloxacin and related derivatives
ES2061481T3 (es) * 1986-12-25 1994-12-16 Daiichi Seiyaku Co Derivados de 3,4-dihidrobenzoazina opticamente activos y procedimiento para la preparacion de los mismos.

Also Published As

Publication number Publication date
PT92219A (pt) 1990-05-31
NO894399D0 (no) 1989-11-06
AU4376589A (en) 1990-05-10
EP0368410A3 (en) 1990-09-05
JPH02178287A (ja) 1990-07-11
DK551689D0 (da) 1989-11-06
CA2002395A1 (en) 1990-05-07
HU895682D0 (en) 1990-01-28
HUT54128A (en) 1991-01-28
EP0368410A2 (en) 1990-05-16
NO894399L (no) 1990-05-08
FI895268A7 (fi) 1990-05-08
FI895268A0 (fi) 1989-11-06
CN1042538A (zh) 1990-05-30
IL92217A0 (en) 1990-07-26

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Legal Events

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AHB Application shelved due to non-payment