DK567887A - Anticholinerg forbindelse, farmaceutisk praeparat deraf og fremgangsmaade til behandling dermed. - Google Patents

Anticholinerg forbindelse, farmaceutisk praeparat deraf og fremgangsmaade til behandling dermed.

Info

Publication number: DK567887A
Authority: DK; Denmark
Prior art keywords: compounds; treatment; anticholinergic; compound; pharmaceutical preparations
Prior art date: 1986-03-17

Application number

DK567887A

Other languages

English (en)

Other versions

DK567887D0 (da

DK170560B1 (da

Inventor

Richard H Hammer

Nicholas S Bodor

Original Assignee

Univ Florida

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-17

Filing date

1987-10-30

Publication date

1987-10-30

1987-10-30 Application filed by Univ Florida filed Critical Univ Florida

1987-10-30 Publication of DK567887D0 publication Critical patent/DK567887D0/da

1987-10-30 Publication of DK567887A publication Critical patent/DK567887A/da

1995-10-23 Application granted granted Critical

1995-10-23 Publication of DK170560B1 publication Critical patent/DK170560B1/da

Links

150000001875 compounds Chemical class 0.000 title abstract 8
238000000034 method Methods 0.000 title abstract 3
239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
230000001078 anti-cholinergic effect Effects 0.000 abstract 3
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
239000004593 Epoxy Substances 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
208000006550 Mydriasis Diseases 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
231100000614 poison Toxicity 0.000 abstract 1
230000007096 poisonous effect Effects 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)

DK567887A 1986-03-17 1987-10-30 Azabicyclobenzenacetat, samt farmaceutisk præparat indeholdende en sådan forbindelse DK170560B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US83994186A	1986-03-17	1986-03-17
US83994186		1986-03-17
US8700533		1987-03-17
PCT/US1987/000533 WO1987005603A1 (en)	1986-03-17	1987-03-17	Anticholinergic compounds, pharmaceutical compositions and method of treatment

Publications (3)

Publication Number	Publication Date
DK567887D0 DK567887D0 (da)	1987-10-30
DK567887A true DK567887A (da)	1987-10-30
DK170560B1 DK170560B1 (da)	1995-10-23

Family

ID=25281041

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK567887A DK170560B1 (da)	1986-03-17	1987-10-30	Azabicyclobenzenacetat, samt farmaceutisk præparat indeholdende en sådan forbindelse

Country Status (14)

Country	Link
EP (1)	EP0238982B1 (da)
JP (1)	JP2672311B2 (da)
KR (1)	KR900007218B1 (da)
AT (1)	ATE86622T1 (da)
CA (1)	CA1328106C (da)
DE (1)	DE3784531T2 (da)
DK (1)	DK170560B1 (da)
ES (1)	ES2044851T3 (da)
FI (1)	FI87213C (da)
IE (1)	IE60645B1 (da)
NO (1)	NO874765L (da)
NZ (1)	NZ219653A (da)
WO (1)	WO1987005603A1 (da)
ZA (1)	ZA871948B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200524577A (en) *	2003-11-04	2005-08-01	Glaxo Group Ltd	Muscarinic acetylcholine receptor antagonists
EP1785421A1 (en) *	2004-08-30	2007-05-16	Ono Pharmaceutical Co., Ltd.	Tropan compound
CN113321648B (zh) *	2021-05-21	2022-02-11	常州康普药业有限公司	一种硫酸阿托品的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2814623A (en) *	1955-12-05	1957-11-26	Upjohn Co	Certain esters of n-methyl scopolamine quaternary ammonium salts
DE1670048C3 (de) *	1966-01-26	1980-09-04	C.H. Boehringer Sohn, 6507 Ingelheim	Neue Norscopolaminderivate
NL7002588A (da) *	1969-03-04	1970-09-08
US3998815A (en) *	1974-06-24	1976-12-21	Interx Research Corporation	1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

1987
- 1987-03-16 IE IE69887A patent/IE60645B1/en not_active IP Right Cessation
- 1987-03-16 CA CA000532123A patent/CA1328106C/en not_active Expired - Fee Related
- 1987-03-17 WO PCT/US1987/000533 patent/WO1987005603A1/en not_active Ceased
- 1987-03-17 NZ NZ219653A patent/NZ219653A/xx unknown
- 1987-03-17 JP JP62502072A patent/JP2672311B2/ja not_active Expired - Lifetime
- 1987-03-17 KR KR1019870701055A patent/KR900007218B1/ko not_active Expired
- 1987-03-17 AT AT87103868T patent/ATE86622T1/de not_active IP Right Cessation
- 1987-03-17 DE DE8787103868T patent/DE3784531T2/de not_active Expired - Lifetime
- 1987-03-17 ES ES87103868T patent/ES2044851T3/es not_active Expired - Lifetime
- 1987-03-17 ZA ZA871948A patent/ZA871948B/xx unknown
- 1987-03-17 EP EP87103868A patent/EP0238982B1/en not_active Expired - Lifetime
- 1987-10-30 DK DK567887A patent/DK170560B1/da not_active IP Right Cessation
- 1987-11-09 FI FI874937A patent/FI87213C/fi not_active IP Right Cessation
- 1987-11-16 NO NO874765A patent/NO874765L/no unknown

Also Published As

Publication number	Publication date
KR900007218B1 (ko)	1990-10-05
CA1328106C (en)	1994-03-29
IE870698L (en)	1987-09-17
DK567887D0 (da)	1987-10-30
EP0238982A1 (en)	1987-09-30
KR880701230A (ko)	1988-07-26
ES2044851T3 (es)	1994-01-16
DK170560B1 (da)	1995-10-23
AU7203187A (en)	1987-10-09
FI87213B (fi)	1992-08-31
FI87213C (fi)	1992-12-10
NO874765L (no)	1988-01-14
JPS63502898A (ja)	1988-10-27
NO874765D0 (no)	1987-11-16
NZ219653A (en)	1990-02-26
JP2672311B2 (ja)	1997-11-05
ZA871948B (en)	1987-09-07
EP0238982B1 (en)	1993-03-10
DE3784531D1 (de)	1993-04-15
FI874937A0 (fi)	1987-11-09
IE60645B1 (en)	1994-08-10
WO1987005603A1 (en)	1987-09-24
ATE86622T1 (de)	1993-03-15
FI874937A7 (fi)	1987-11-09
AU595307B2 (en)	1990-03-29
DE3784531T2 (de)	1993-06-24

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Legal Events

Date	Code	Title	Description
1995-10-23	B1	Patent granted (law 1993)
1999-03-08	PBP	Patent lapsed