DK568885A - Sure indolforbindelser og deres anvendelse som antiallergiske midler - Google Patents

Sure indolforbindelser og deres anvendelse som antiallergiske midler Download PDF

Info

Publication number: DK568885A
Authority: DK; Denmark
Prior art keywords: carbon atoms; radical; substituted; compounds; amino group
Prior art date: 1984-12-10

Application number

DK568885A

Other languages

English (en)

Other versions

DK568885D0 (da

DK174104B1 (da

Inventor

David T Connor

Paul C Unangst

S Russell Stabler

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-10

Filing date

1985-12-09

Publication date

1986-06-11

1985-12-09 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1985-12-09 Publication of DK568885D0 publication Critical patent/DK568885D0/da

1986-06-11 Publication of DK568885A publication Critical patent/DK568885A/da

2002-06-17 Application granted granted Critical

2002-06-17 Publication of DK174104B1 publication Critical patent/DK174104B1/da

Links

150000001875 compounds Chemical class 0.000 title abstract 5
239000000043 antiallergic agent Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 12
125000003277 amino group Chemical group 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
BNJMRELGMDUDDB-UHFFFAOYSA-N $l^{1}-sulfanylbenzene Chemical compound [S]C1=CC=CC=C1 BNJMRELGMDUDDB-UHFFFAOYSA-N 0.000 abstract 2
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 2
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
-1 phenylsulphinyl radical Chemical class 0.000 abstract 2
150000003254 radicals Chemical class 0.000 abstract 2
125000003396 thiol group Chemical class [H]S* 0.000 abstract 2
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
BQIKRTGTPBOIMK-UHFFFAOYSA-N [O]C[O] Chemical compound [O]C[O] BQIKRTGTPBOIMK-UHFFFAOYSA-N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Lubricants (AREA)
Cosmetics (AREA)

DK198505688A 1984-12-10 1985-12-09 1-Tetrazol-5-yl-1H-indol-carboxamidderivater, fremgangsmåde til fremstilling deraf samt lægemidde indeholdende forbindelserne DK174104B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US68011684A	1984-12-10	1984-12-10
US68011684		1984-12-10
US78811185		1985-10-21
US06/788,111 US4675332A (en)	1984-12-10	1985-10-21	Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents

Publications (3)

Publication Number	Publication Date
DK568885D0 DK568885D0 (da)	1985-12-09
DK568885A true DK568885A (da)	1986-06-11
DK174104B1 DK174104B1 (da)	2002-06-17

Family

ID=27102395

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198505688A DK174104B1 (da)	1984-12-10	1985-12-09	1-Tetrazol-5-yl-1H-indol-carboxamidderivater, fremgangsmåde til fremstilling deraf samt lægemidde indeholdende forbindelserne

Country Status (18)

Country	Link
US (1)	US4675332A (da)
EP (1)	EP0186367B1 (da)
JP (1)	JPH0653736B2 (da)
KR (1)	KR890000292B1 (da)
CN (1)	CN1005974B (da)
AT (1)	ATE86252T1 (da)
AU (1)	AU576131B2 (da)
CA (1)	CA1259317A (da)
DE (1)	DE3587148T2 (da)
DK (1)	DK174104B1 (da)
ES (1)	ES8700252A1 (da)
FI (1)	FI84719C (da)
GR (1)	GR852948B (da)
IE (1)	IE58554B1 (da)
NO (1)	NO159653C (da)
NZ (1)	NZ214480A (da)
PH (1)	PH24075A (da)
PT (1)	PT81637B (da)

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LU87611A1 (fr) *	1989-10-20	1991-05-07	Oreal	Composition tinctoriale pour fibres keratiniques contenant des precurseurs de colorants par oxydation et des coupleurs amino indoliques,procedes de teinture mettant en oeuvre ces compositions et composes nouveaux
US5051442A (en) *	1990-04-25	1991-09-24	Merrell Dow Pharmaceuticals Inc.	3-indolyl thioacetate derivatives and NMDA receptor antagonistic use thereof
US5095031A (en) *	1990-08-20	1992-03-10	Abbott Laboratories	Indole derivatives which inhibit leukotriene biosynthesis
US5189054A (en) *	1990-11-02	1993-02-23	Merrell Dow Pharmaceuticals Inc.	3-amidoindolyl derivatives and pharmaceutical compositions thereof
CA2054339C (en) *	1990-11-02	2002-12-24	Francesco G. Salituro	3-amidoindolyl derivatives
US5599774A (en) *	1992-01-22	1997-02-04	Imperial Chemical Industries Plc	N-arylindoles and their use as herbicides
US5395817A (en) *	1992-01-22	1995-03-07	Imperial Chemical Industries Plc	N-arylindoles and their use as herbicides
US5424329A (en) *	1993-08-18	1995-06-13	Warner-Lambert Company	Indole-2-carboxamides as inhibitors of cell adhesion
GB9716657D0 (en)	1997-08-07	1997-10-15	Zeneca Ltd	Chemical compounds
GB9803226D0 (en)	1998-02-17	1998-04-08	Zeneca Ltd	Chemical compounds
GB9902459D0 (en) *	1999-02-05	1999-03-24	Zeneca Ltd	Chemical compounds
GB9902461D0 (en)	1999-02-05	1999-03-24	Zeneca Ltd	Chemical compounds
GB9902455D0 (en) *	1999-02-05	1999-03-24	Zeneca Ltd	Chemical compounds
GB9902453D0 (en)	1999-02-05	1999-03-24	Zeneca Ltd	Chemical compounds
GB9902452D0 (en)	1999-02-05	1999-03-24	Zeneca Ltd	Chemical compounds
GB0000625D0 (en)	2000-01-13	2000-03-01	Zeneca Ltd	Chemical compounds
US6436965B1 (en)	2000-03-02	2002-08-20	Merck Frosst Canada & Co.	PDE IV inhibiting amides, compositions and methods of treatment
EP1314733A1 (en) *	2001-11-22	2003-05-28	Aventis Pharma Deutschland GmbH	Indole-2-carboxamides as factor Xa inhibitors
GB0217920D0 (en) *	2002-04-23	2002-09-11	Aventis Pharm Prod Inc	Interleukin-4 Gene Expression inhibitors
ATE438621T1 (de) *	2002-04-23	2009-08-15	Aventis Pharma Inc	3-(substitutierte amino)-1h-indole-2- carbonsäureester und 3-(substitutierte amino)- benzoäbüthiophen-2-carbonsäureester verbindungen als inhibitoren der interleukin-4 genexpression
AU2003258145A1 (en) *	2002-08-07	2004-02-25	Idenix (Cayman) Limited	Substituted phenylindoles for the treatment of hiv
EP1479677A1 (en) *	2003-05-19	2004-11-24	Aventis Pharma Deutschland GmbH	New indole derivatives as factor xa inhibitors
EP1644360A1 (en) *	2003-06-05	2006-04-12	Warner-Lambert Company LLC	3-substituted indoles and derivatives thereof as therapeutic agents
DE602004020685D1 (de) *	2003-12-11	2009-05-28	Aventis Pharma Inc	Substituierte 1h-pyrroloä3,2-b, 3,2-c und 2,3-cüpyridin-2-carbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i-epsilon
MXPA06014535A (es)	2004-06-18	2007-06-05	Biolipox Ab	Indoles utiles en el tratamiento de la inflamacion.
BRPI0519774A2 (pt)	2005-01-19	2009-02-10	Biolipox Ab	composto ou um sal farmaceuticamente aceitÁvel do mesmo, formulaÇço farmacÊutica, uso de um composto ou um sal farmaceuticamente aceitÁvel do mesmo, mÉtodo de tratamento de uma doenÇa em que inibiÇço da atividade de um membro da famÍlia mapeg É desejada e/ou necessÁria, produto combinado, e, processo para a preparaÇço de um composto
PT1888548E (pt)	2005-05-26	2012-10-30	Neuron Systems Inc	Derivado de quinolina para o tratamento de doenças da retina
WO2011072141A1 (en)	2009-12-11	2011-06-16	Neuron Systems, Inc.	Compositions and methods for the treatment of macular degeneration
WO2012081893A2 (ko) *	2010-12-13	2012-06-21	한국화학연구원	신규한 3-인돌리논 유도체 및 이를 포함하는 조성물
RU2015120478A (ru)	2012-12-20	2017-01-25	Альдейра Терапьютикс, Инк.	Пери-карбинолы
CA2898631C (en)	2013-01-23	2023-06-13	Aldeyra Therapeutics, Inc.	Toxic aldehyde related diseases and treatment
SG11201505599YA (en)	2013-01-25	2015-08-28	Aldeyra Therapeutics Inc	Novel traps in the treatment of macular degeneration
CN118724806A (zh)	2015-08-21	2024-10-01	奥尔德拉医疗公司	氘化化合物和其用途
US11129823B2 (en)	2016-05-09	2021-09-28	Aldeyra Therapeutics, Inc.	Combination treatment of ocular inflammatory disorders and diseases
MX2019010576A (es)	2017-03-16	2019-10-07	Aldeyra Therapeutics Inc	Compuestos polimorficos y usos de los mismos.
JP7311162B2 (ja)	2017-10-10	2023-07-19	アルデイラセラピューティクス，インコーポレイテッド	炎症性障害の処置
US11690824B2 (en)	2018-04-10	2023-07-04	The General Hospital Corporation	Antibacterial compounds
WO2020033344A1 (en)	2018-08-06	2020-02-13	Aldeyra Therapeutics, Inc.	Polymorphic compounds and uses thereof
US12098132B2 (en)	2019-05-02	2024-09-24	Aldeyra Therapeutics, Inc.	Process for preparation of aldehyde scavenger and intermediates
CN113784954A (zh)	2019-05-02	2021-12-10	奥尔德拉医疗公司	多晶型化合物和其用途
CN112028815A (zh) *	2019-06-03	2020-12-04	中国药科大学	吲哚类衍生物及其医药用途
CA3175856A1 (en)	2020-05-13	2021-11-18	Todd Brady	Pharmaceutical formulations and uses thereof

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US3417096A (en) *	1965-07-01	1968-12-17	Bristol Myers Co	Certain 5(1-benzoyl-3-indolylmethyl) tetrazoles
US4316904A (en) *	1978-06-05	1982-02-23	Brown Richard E	Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity
US4432986A (en) *	1979-06-18	1984-02-21	Riker Laboratories, Inc.	Tetrazoles bonded to certain polycyclic aromatic systems and anti-allergic use thereof
US4333943A (en) *	1980-04-24	1982-06-08	Miles Laboratories, Inc.	Ethyl 3-(3-indolyl)-3-(5-tetrazolyl) propionate compounds used as anti-hypertensive agents
DE3131527A1 (de) *	1981-08-08	1983-02-24	Kali-Chemie Pharma Gmbh, 3000 Hannover	1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB2111050B (en) *	1981-11-19	1985-09-11	Ciba Geigy Ag	N-substituted-2-pyridylindoles
US4567201A (en) *	1981-11-25	1986-01-28	Takeda Chemical Industries, Ltd.	Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof
US4436746A (en) *	1982-09-30	1984-03-13	Ciba-Geigy Corporation	Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
US4511573A (en) *	1983-05-17	1985-04-16	Ciba-Geigy Corporation	3-Substituted-2-(heteroaryl) indoles
US4536505A (en) *	1983-05-17	1985-08-20	Ciba-Geigy Corporation	Certain N-(pyridyl) indoles
EP0146243A1 (en) *	1983-10-31	1985-06-26	Merck Frosst Canada Inc.	Lipoxygenase inhibitors
US4581354A (en) *	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
IE58555B1 (en) *	1984-12-10	1993-10-06	Warner Almbert Company	Novel benzothiophenes and benzofurans having antiallergy activity

1985
- 1985-10-21 US US06/788,111 patent/US4675332A/en not_active Expired - Lifetime
- 1985-11-13 IE IE284185A patent/IE58554B1/en not_active IP Right Cessation
- 1985-11-29 AU AU50508/85A patent/AU576131B2/en not_active Ceased
- 1985-12-04 FI FI854821A patent/FI84719C/fi not_active IP Right Cessation
- 1985-12-06 PH PH33140A patent/PH24075A/en unknown
- 1985-12-09 NZ NZ214480A patent/NZ214480A/en unknown
- 1985-12-09 JP JP60275227A patent/JPH0653736B2/ja not_active Expired - Fee Related
- 1985-12-09 DK DK198505688A patent/DK174104B1/da not_active IP Right Cessation
- 1985-12-09 GR GR852948A patent/GR852948B/el unknown
- 1985-12-09 NO NO854941A patent/NO159653C/no unknown
- 1985-12-10 KR KR1019850009255A patent/KR890000292B1/ko not_active Expired
- 1985-12-10 ES ES549768A patent/ES8700252A1/es not_active Expired
- 1985-12-10 CA CA000497268A patent/CA1259317A/en not_active Expired
- 1985-12-10 DE DE8585308948T patent/DE3587148T2/de not_active Expired - Fee Related
- 1985-12-10 CN CN85109061.3A patent/CN1005974B/zh not_active Expired
- 1985-12-10 PT PT81637A patent/PT81637B/pt not_active IP Right Cessation
- 1985-12-10 EP EP85308948A patent/EP0186367B1/en not_active Expired - Lifetime
- 1985-12-10 AT AT85308948T patent/ATE86252T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU576131B2 (en)	1988-08-11
AU5050885A (en)	1986-06-19
PT81637B (pt)	1988-02-17
FI854821A7 (fi)	1986-06-11
NO854941L (no)	1986-06-11
CN1005974B (zh)	1989-12-06
ATE86252T1 (de)	1993-03-15
FI854821A0 (fi)	1985-12-04
PT81637A (en)	1986-01-01
NO159653C (no)	1989-01-25
NO159653B (no)	1988-10-17
FI84719C (fi)	1992-01-10
CA1259317A (en)	1989-09-12
DK568885D0 (da)	1985-12-09
ES8700252A1 (es)	1986-10-16
US4675332A (en)	1987-06-23
CN85109061A (zh)	1987-01-21
JPH0653736B2 (ja)	1994-07-20
FI84719B (fi)	1991-09-30
KR860004882A (ko)	1986-07-14
EP0186367A2 (en)	1986-07-02
IE58554B1 (en)	1993-10-06
NZ214480A (en)	1988-05-30
DE3587148D1 (de)	1993-04-08
EP0186367B1 (en)	1993-03-03
JPS61191683A (ja)	1986-08-26
ES549768A0 (es)	1986-04-16
GR852948B (da)	1986-04-11
DK174104B1 (da)	2002-06-17
DE3587148T2 (de)	1993-07-15
PH24075A (en)	1990-03-05
KR890000292B1 (ko)	1989-03-13
IE852841L (en)	1986-06-10
EP0186367A3 (en)	1988-01-07

Legal Events

Date	Code	Title	Description
2002-06-17	B1	Patent granted (law 1993)
2004-08-09	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK568885D0 (da)	1985-12-09	Sure indolforbindelser og deres anvendelse som antiallergiske midler
FI944394A0 (fi)	1994-09-22	Kinuklidiinijohdannaisia P-aineen antagonisteina
ES539446A0 (es)	1986-06-01	Un procedimiento para preparar un derivado de dihidropiridazinona
ES8404990A1 (es)	1984-05-16	Un procedimiento para la preparacion de derivados de prolina.
ATE66915T1 (de)	1991-09-15	Dihydropyridine.
DK527984D0 (da)	1984-11-06	11-substituerede 5h,11h-pyrrolo(2,1-c)(1,4)benzoxazepiner eller farmaceutisk acceptable salte deraf, deres fremstilling og mellemprodukter hertil samt deres anvendelse som antipsychotika og analgetika
ES546377A0 (es)	1987-04-01	Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas.
NO985389L (no)	1999-01-20	Heksahydro-pyrido (4,3-B)indolderivater som antipsykotiske legemidler
MX11866A (es)	1993-12-01	Nuevas cicloalquilamidas y procedimiento para su preparacion.
DK407885A (da)	1986-03-13	7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner
NZ332687A (en)	2000-05-26	use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
NO853551L (no)	1986-03-13	Fremgangsmaate ved fremstilling av prolinderivater og lignende forbindelser med antihypertensiv aktivitet.
DK96086A (da)	1986-09-05	8-thiotetrahydroquinolinderivater, deres fremstilling og anvendelse som laegemidler
ES8707729A1 (es)	1987-08-16	Un procedimiento para la preparacion de hexahidroarilquinolizinas sustituidas.
DK573981A (da)	1982-07-03	Fremgangsmaade til fremstilling af cis-c-3",c4"-carbonatderivater af o-demethyl-oleandomycin og mellemprodukter herfor
ES550817A0 (es)	1987-09-01	Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas
DK316986A (da)	1987-01-06	Kemiske forbindelser, som er phosphodiesterase type iii inhibitorer
DE3781044D1 (de)	1992-09-17	Prophylaktische und heilende zusammensetzung enthaltende eine 8-chlorbenzothiazepin-verbindung und dessen verwendung.