DK579688A - Imidazo(2,1-b)benzothiazoler og syreadditionssalte deraf, deres fremstilling samt laegemidler med indhold deraf - Google Patents

Imidazo(2,1-b)benzothiazoler og syreadditionssalte deraf, deres fremstilling samt laegemidler med indhold deraf

Info

Publication number: DK579688A
Authority: DK; Denmark
Prior art keywords: preparation; benzothiazoles; imidazo; contents; alkyl
Prior art date: 1987-10-20

Application number

DK579688A

Other languages

English (en)

Other versions

DK170024B1 (da

DK579688D0 (da

Inventor

Charles John Robert Hedgecock

David Paul Kay

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-20

Filing date

1988-10-18

Publication date

1989-04-21

1988-10-18 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1988-10-18 Publication of DK579688D0 publication Critical patent/DK579688D0/da

1989-04-21 Publication of DK579688A publication Critical patent/DK579688A/da

1995-05-01 Application granted granted Critical

1995-05-01 Publication of DK170024B1 publication Critical patent/DK170024B1/da

Links

150000003839 salts Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
BQIKRTGTPBOIMK-UHFFFAOYSA-N [O]C[O] Chemical compound [O]C[O] BQIKRTGTPBOIMK-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000003368 amide group Chemical group 0.000 abstract 1
-1 aralkoxy Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000002483 medication Methods 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Hematology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Adhesives Or Adhesive Processes (AREA)
Photoreceptors In Electrophotography (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK579688A 1987-10-20 1988-10-18 Imidazo(2,1-b)thiazolderivater, deres fremstilling, mellemprodukter til anvendelse i forbindelse hermed, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold heraf DK170024B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878724566A GB8724566D0 (en)	1987-10-20	1987-10-20	Chemical compounds
GB8724566		1987-10-20

Publications (3)

Publication Number	Publication Date
DK579688D0 DK579688D0 (da)	1988-10-18
DK579688A true DK579688A (da)	1989-04-21
DK170024B1 DK170024B1 (da)	1995-05-01

Family

ID=10625613

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK579688A DK170024B1 (da)	1987-10-20	1988-10-18	Imidazo(2,1-b)thiazolderivater, deres fremstilling, mellemprodukter til anvendelse i forbindelse hermed, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold heraf

Country Status (16)

Country	Link
US (1)	US4895863A (da)
EP (1)	EP0313458B1 (da)
JP (1)	JPH01193274A (da)
AT (1)	ATE92928T1 (da)
AU (1)	AU613413B2 (da)
CA (1)	CA1331991C (da)
DE (1)	DE3883140T2 (da)
DK (1)	DK170024B1 (da)
ES (1)	ES2059552T3 (da)
GB (2)	GB8724566D0 (da)
GR (1)	GR3009703T3 (da)
HU (1)	HU201769B (da)
MX (1)	MX173422B (da)
PT (1)	PT88795B (da)
RU (1)	RU2014334C1 (da)
ZA (1)	ZA887433B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8908846D0 (en) *	1989-04-19	1989-06-07	Roussel Lab Ltd	Chemical compounds
GB8908845D0 (en) *	1989-04-19	1989-06-07	Roussel Lab Ltd	Chemical compounds
EP0524055A1 (fr) *	1991-07-19	1993-01-20	Synthelabo	Dérivés d'imidazo[2,1-b]benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique
FR2679231B1 (fr) *	1991-07-19	1994-01-14	Synthelabo	Derives d'imidazo [2,1-b] benzothiazole-3-acetamide, leur preparation et leur application, en therapeutique.
FR2679136A1 (fr) *	1991-07-19	1993-01-22	Synthelabo	Medicaments et compositions pharmaceutiques a base de derives d'imidazo[2,1-b]benzothiazole-3-acetamide.
FR2679233B1 (fr) *	1991-07-19	1993-10-15	Synthelabo	Derives d'imidazo [2,1-b] benzothiazole-3-acetamide, leur preparation et leur application en therapeutique.
FR2679232B1 (fr) *	1991-07-19	1994-01-14	Synthelabo	Derives d'alpha-hydroxyimidazo [2,1-b] benzothiazole-3-acetamide, leur preparation et leur application en therapeutique.
FR2699920B1 (fr) *	1992-12-24	1995-02-10	Synthelabo	Dérivés d'imidazo [2,1-b] benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique.
FR2699921B1 (fr) *	1992-12-30	1995-02-10	Synthelabo	Dérivés d'acide 2-(thien-2-yl)imidazo[2,1-b]benzothiazole-3-acétique, leur préparation et leur application en thérapeutique.
FR2735777B1 (fr) *	1995-06-21	1997-09-12	Sanofi Sa	Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
RU2120965C1 (ru) *	1995-07-11	1998-10-27	Евгений Яковлевич Косицкий	Водка "вятская"
DE59707350D1 (de) *	1996-04-04	2002-07-04	Rolic Ag Zug	Imidazothiazol-Derivate als komponente flüssigkristalline Mischungen
RU2165929C1 (ru) *	2000-01-26	2001-04-27	Ярославский государственный технический университет	Гетероциклические о-дикарбонитрилы
DE10004572A1 (de)	2000-02-02	2001-08-09	Boehringer Ingelheim Pharma	Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
AR039774A1 (es)	2002-05-01	2005-03-02	Wyeth Corp	6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AR039475A1 (es)	2002-05-01	2005-02-23	Wyeth Corp	6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
GT200600380A (es) *	2005-08-24	2007-03-29		Proceso para la preparacion de inhibidores de beta-lactamasa
TWI648282B (zh)	2014-03-27	2019-01-21	印度商托仁特生技有限公司	新熔合咪唑苯并噻唑化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH621126A5 (da) *	1974-02-07	1981-01-15	Plantex Ltd
US4464384A (en) *	1981-12-23	1984-08-07	Yamanouchi Pharmaceutical Co., Ltd.	2-Phenylimidazo[2,1-b]benzothiazole compounds, salts thereof, process of producing them, and pharmaceutical compositions containing them
US4721721A (en) *	1984-12-18	1988-01-26	Rorer Pharmaceutical Corporation	6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
IL78834A (en) *	1985-05-23	1992-07-15	Smithkline Beckman Corp	2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines
ZW24186A1 (en) *	1985-12-12	1987-07-08	Smithkline Beckman Corp	Inhibition of the 5-lipoxygenase pathway

1987
- 1987-10-20 GB GB878724566A patent/GB8724566D0/en active Pending
1988
- 1988-10-04 ZA ZA887433A patent/ZA887433B/xx unknown
- 1988-10-14 JP JP63257426A patent/JPH01193274A/ja active Pending
- 1988-10-18 US US07/259,285 patent/US4895863A/en not_active Expired - Fee Related
- 1988-10-18 DK DK579688A patent/DK170024B1/da not_active IP Right Cessation
- 1988-10-18 MX MX013455A patent/MX173422B/es unknown
- 1988-10-19 HU HU885344A patent/HU201769B/hu not_active IP Right Cessation
- 1988-10-19 DE DE88402634T patent/DE3883140T2/de not_active Expired - Fee Related
- 1988-10-19 ES ES88402634T patent/ES2059552T3/es not_active Expired - Lifetime
- 1988-10-19 PT PT88795A patent/PT88795B/pt not_active IP Right Cessation
- 1988-10-19 AU AU23978/88A patent/AU613413B2/en not_active Ceased
- 1988-10-19 EP EP88402634A patent/EP0313458B1/fr not_active Expired - Lifetime
- 1988-10-19 CA CA000580679A patent/CA1331991C/en not_active Expired - Fee Related
- 1988-10-19 AT AT88402634T patent/ATE92928T1/de not_active IP Right Cessation
- 1988-10-19 GB GB8824492A patent/GB2211186B/en not_active Expired - Lifetime
1992
- 1992-01-14 RU SU925010659A patent/RU2014334C1/ru active
1993
- 1993-11-11 GR GR930400671T patent/GR3009703T3/el unknown

Also Published As

Publication number	Publication date
DK170024B1 (da)	1995-05-01
AU613413B2 (en)	1991-08-01
HUT50836A (en)	1990-03-28
EP0313458A2 (fr)	1989-04-26
GB8724566D0 (en)	1987-11-25
GB2211186A (en)	1989-06-28
EP0313458B1 (fr)	1993-08-11
HU201769B (en)	1990-12-28
RU2014334C1 (ru)	1994-06-15
MX173422B (es)	1994-03-03
DK579688D0 (da)	1988-10-18
ATE92928T1 (de)	1993-08-15
ZA887433B (en)	1990-01-31
DE3883140T2 (de)	1994-01-13
US4895863A (en)	1990-01-23
GB2211186B (en)	1991-07-31
GB8824492D0 (en)	1988-11-23
MX13455A (es)	1993-10-01
EP0313458A3 (en)	1990-10-31
AU2397888A (en)	1989-04-20
PT88795B (pt)	1993-01-29
JPH01193274A (ja)	1989-08-03
ES2059552T3 (es)	1994-11-16
GR3009703T3 (da)	1994-02-28
DE3883140D1 (de)	1993-09-16
CA1331991C (en)	1994-09-13

Legal Events

Date	Code	Title	Description
1995-05-01	B1	Patent granted (law 1993)
1996-06-17	PBP	Patent lapsed

Publication	Publication Date	Title
DK579688D0 (da)	1988-10-18	Imidazo(2,1-b)benzothiazoler og syreadditionssalte deraf, deres fremstilling samt laegemidler med indhold deraf
DK0494819T3 (da)	1996-08-12	Hidtil ukendte phenylimidazolidiner, deres fremstilling, anvendelse som lægemidler samt farmaceutiske præparater med indhold heraf
PT91574A (pt)	1990-03-30	Procede de preparation de n-cycloalkyle benzyamines utiles comme medicaments
SE8802412D0 (sv)	1988-06-28	Thiourea derivatives
DK488588D0 (da)	1988-09-02	Sulfonamid-forbindelser, farmaceutiske praeparater indeholdende disse og anvendelse af forbindelserne til fremstilling af antiarytmiske laegemidler
ES2057802T3 (es)	1994-10-16	Nuevos derivados de 3-amino-cromano, procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK461687D0 (da)	1987-09-04	Benzhydryloxyethylpiperidinderivater og salte deraf samt deres fremstilling og anvendelse.
DK302886D0 (da)	1986-06-26	4-amino-2-(imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-(n-(3-trifluormethyl-phenyl)-amider) til profylakse og terapi af thromboser samt deres anvendelse til fremstilling af antithrombotisk virksomme laegemidler
DK470888D0 (da)	1988-08-23	Imidazobenzodiazepinderivater, deres fresmtilling samt laegemidler med indholdd deraf
PT84161B (pt)	1989-07-31	Processo para a preparacao de derivados de 3-acilaminometil-imidazo-{1,2-a}-piridinas e de composicoes farmaceuticas que os contem
NZ216125A (en)	1988-10-28	Isoxazoles and pharmaceutical compositions
DK351886A (da)	1987-01-26	4-oh-quinolincarboxylsyrederivater, deres fremstilling, mellemprodukter ved deres fremstilling samt laegemidler med indhold deraf
DK96086D0 (da)	1986-03-03	8-thiotetrahydroquinolinderivater, deres fremstilling og anvendelsesom laegemidler
ES8401456A1 (es)	1983-12-01	Procedimiento para la preparacion de 2-aminometilfenoles.
DK280883A (da)	1983-12-19	Organophosphat-derivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som midler til bekaempelse af skadelige organismer
DK222588D0 (da)	1988-04-22	5-quinoxalyl-imidazolidin-2,4-dioner, deres fremstilling og anvendelse som laegemidler
SE8006142L (sv)	1981-03-05	1,2,4-triazol-3-tioler
ES507269A0 (es)	1982-09-01	Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano.
ES507281A0 (es)	1982-10-01	Procedimiento para la preparacion de una nueva tiovinil-3 cefalosporina.
IL69931A (en)	1987-03-31	N-(6-chloro-pyrazin-2-yl)-4-hydroxy-2h-1,2-benzothiazine-3-carboxamide-1,1-dioxides,their preparation and pharmaceutical compositions containing them
IL82419A (en)	1991-06-10	3-amino-dihydropyridines,their preparation and medicaments containing them
SU1179926A3 (ru)	1985-09-15	"cпocoб пoлучehия пpoизboдhыx cemиkapбaзидa или иx kиcлotho-aддиtиbhыx coлeй"