DK59281A - Fremgangsmaade til fremstilling af phenylpiperazinderivater af 1,3,4-oxadiazolylphenolder - Google Patents

Fremgangsmaade til fremstilling af phenylpiperazinderivater af 1,3,4-oxadiazolylphenolder

Info

Publication number: DK59281A
Authority: DK; Denmark
Prior art keywords: oxadiazolylphenolds; piperazine derivatives; phenyl piperazine; preparing phenyl; preparing
Prior art date: 1980-02-13

Application number

DK59281A

Other languages

English (en)

Other versions

DK149888B (da

DK149888C (da

Inventor

P C Thieme

A Franke

D Lenke

D D Lehmann

J Gries

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-13

Filing date

1981-02-12

Publication date

1981-08-14

1981-02-12 Application filed by Basf Ag filed Critical Basf Ag

1981-08-14 Publication of DK59281A publication Critical patent/DK59281A/da

1986-10-20 Publication of DK149888B publication Critical patent/DK149888B/da

1987-05-04 Application granted granted Critical

1987-05-04 Publication of DK149888C publication Critical patent/DK149888C/da

Links

238000000034 method Methods 0.000 title abstract 2
YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical class C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 title 1
DTUMKFRBWKKQIA-UHFFFAOYSA-N 1-phenyl-1-piperazin-1-ylpropan-1-ol Chemical class C=1C=CC=CC=1C(O)(CC)N1CCNCC1 DTUMKFRBWKKQIA-UHFFFAOYSA-N 0.000 abstract 1
206010020852 Hypertonia Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
OINXXHYENYVYPB-UHFFFAOYSA-N fenadiazole Chemical class OC1=CC=CC=C1C1=NN=CO1 OINXXHYENYVYPB-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK59281A 1980-02-13 1981-02-12 Analogifremgangsmaade til fremstilling af 1-(1,3,4-oxadiazolyl-2-phenoxy)-3-(4-phenylpiperazinyl)-propan-2-oler eller fysiologisk acceptable syreadditionssalte heraf DK149888C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3005287		1980-02-13
DE19803005287 DE3005287A1 (de)	1980-02-13	1980-02-13	Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel

Publications (3)

Publication Number	Publication Date
DK59281A true DK59281A (da)	1981-08-14
DK149888B DK149888B (da)	1986-10-20
DK149888C DK149888C (da)	1987-05-04

Family

ID=6094461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK59281A DK149888C (da)	1980-02-13	1981-02-12	Analogifremgangsmaade til fremstilling af 1-(1,3,4-oxadiazolyl-2-phenoxy)-3-(4-phenylpiperazinyl)-propan-2-oler eller fysiologisk acceptable syreadditionssalte heraf

Country Status (18)

Country	Link
US (1)	US4353904A (da)
EP (1)	EP0034276B1 (da)
JP (1)	JPS56138174A (da)
AT (1)	ATE5256T1 (da)
AU (1)	AU536582B2 (da)
CA (1)	CA1159069A (da)
CS (1)	CS219852B2 (da)
DD (1)	DD156262A5 (da)
DE (2)	DE3005287A1 (da)
DK (1)	DK149888C (da)
ES (1)	ES8201578A1 (da)
FI (1)	FI65616C (da)
HU (1)	HU182290B (da)
IE (1)	IE50864B1 (da)
IL (1)	IL61989A (da)
NO (1)	NO156900C (da)
SU (1)	SU1001856A3 (da)
ZA (1)	ZA81927B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3030530A1 (de) *	1980-08-13	1982-03-18	Beiersdorf Ag, 2000 Hamburg	Alkyl- und cycloalkylsubstituierte 2-(2-(-hydroxy-3-tert-butylamino-propoxy)-5-acylaminophenyl)-1,3,4-oxadiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen
DE3101502A1 (de) *	1981-01-19	1982-08-26	Basf Ag, 6700 Ludwigshafen	Phenylpiperazinderivate von hetarylphenolen und hetarylanilinen, ihre hersttellung und diese enthaltendetherapeutische mittel
DE3130252A1 (de) *	1981-07-31	1983-02-17	A. Nattermann & Cie GmbH, 5000 Köln	6-(5-((omega)-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydro-pyridazine und deren saeureadditionssalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4567264A (en) *	1983-05-18	1986-01-28	Syntex (U.S.A.) Inc.	Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) *	1983-05-18	1985-12-10	Syntex (U.S.A.) Inc.	Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
DE3423429A1 (de) *	1984-06-26	1986-01-02	Beiersdorf Ag, 2000 Hamburg	Substituierte phenoxyalkylaminopropanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
GB8911158D0 (en) *	1989-05-16	1989-07-05	Janssen Pharmaceutica Nv	Antiviral pyridazinamines
US5070090A (en) *	1989-05-15	1991-12-03	Janssen Pharmaceutica N.V.	Antipicorpaviral herterocyclic-substituted morpholinyl alkylphenol ethers
ES2162792T3 (es) *	1991-09-18	2002-01-16	Glaxo Group Ltd	Derivados de benzanilida como antagonistas de 5-ht1d.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MC598A1 (fr) *	1966-02-16	1967-03-21	Mauvernay Roland Yves	Nouveaux composés chimiques et procédé pour leur préparation
GB1174411A (en) *	1966-03-02	1969-12-17	Aspro Nicholas Ltd	Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
MC641A1 (fr) *	1967-03-08	1967-12-05	Mauvernay Roland Yves	Nouveaux composés chimiques et procédé pour leur préparation
BE756127A (fr) *	1969-09-12	1971-03-15	Hoechst Ag	Ethers heterocycliques et leur preparation
GB1317479A (en) *	1970-11-10	1973-05-16	Pfizer Ltd	1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives
DE2263211A1 (de) *	1972-12-23	1974-07-04	Boehringer Sohn Ingelheim	Neue arylpiperazine und verfahren zu ihrer herstellung
DE2811638A1 (de) *	1978-03-17	1979-09-20	Beiersdorf Ag	Substituierte aryloxy-aminopropanole und verfahren zu deren herstellung

1980
- 1980-02-13 DE DE19803005287 patent/DE3005287A1/de not_active Withdrawn
1981
- 1981-01-26 US US06/228,370 patent/US4353904A/en not_active Expired - Fee Related
- 1981-01-26 IL IL61989A patent/IL61989A/xx unknown
- 1981-01-28 DE DE8181100592T patent/DE3161340D1/de not_active Expired
- 1981-01-28 EP EP81100592A patent/EP0034276B1/de not_active Expired
- 1981-01-28 AT AT81100592T patent/ATE5256T1/de not_active IP Right Cessation
- 1981-01-30 CA CA000369751A patent/CA1159069A/en not_active Expired
- 1981-02-10 FI FI810380A patent/FI65616C/fi not_active IP Right Cessation
- 1981-02-10 JP JP1759181A patent/JPS56138174A/ja active Granted
- 1981-02-12 HU HU81347A patent/HU182290B/hu not_active IP Right Cessation
- 1981-02-12 DD DD81227589A patent/DD156262A5/de not_active IP Right Cessation
- 1981-02-12 NO NO810480A patent/NO156900C/no unknown
- 1981-02-12 IE IE276/81A patent/IE50864B1/en unknown
- 1981-02-12 DK DK59281A patent/DK149888C/da active
- 1981-02-12 ES ES499363A patent/ES8201578A1/es not_active Expired
- 1981-02-12 AU AU67245/81A patent/AU536582B2/en not_active Ceased
- 1981-02-12 ZA ZA00810927A patent/ZA81927B/xx unknown
- 1981-02-12 SU SU813241898A patent/SU1001856A3/ru active
- 1981-02-12 CS CS811016A patent/CS219852B2/cs unknown

Also Published As

Publication number	Publication date
IE810276L (en)	1981-08-13
CA1159069A (en)	1983-12-20
EP0034276B1 (de)	1983-11-09
NO810480L (no)	1981-08-14
DD156262A5 (de)	1982-08-11
ES499363A0 (es)	1981-12-16
AU6724581A (en)	1981-08-20
HU182290B (en)	1983-12-28
ES8201578A1 (es)	1981-12-16
NO156900C (no)	1987-12-16
DK149888B (da)	1986-10-20
AU536582B2 (en)	1984-05-10
IL61989A (en)	1983-12-30
ZA81927B (en)	1982-03-31
ATE5256T1 (de)	1983-11-15
US4353904A (en)	1982-10-12
FI65616B (fi)	1984-02-29
DE3161340D1 (en)	1983-12-15
FI810380L (fi)	1981-08-14
NO156900B (no)	1987-09-07
EP0034276A3 (en)	1981-11-25
SU1001856A3 (ru)	1983-02-28
EP0034276A2 (de)	1981-08-26
JPH0229673B2 (da)	1990-07-02
DK149888C (da)	1987-05-04
DE3005287A1 (de)	1981-08-20
FI65616C (fi)	1984-06-11
JPS56138174A (en)	1981-10-28
IE50864B1 (en)	1986-08-06
IL61989A0 (en)	1981-02-27
CS219852B2 (en)	1983-03-25

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