DK595483A - Substituerede imidazopyridiner, imidazopyraziner og imidazotriaziner og fremgangsmaade til fremstilling af saadanne forbindelser - Google Patents
Substituerede imidazopyridiner, imidazopyraziner og imidazotriaziner og fremgangsmaade til fremstilling af saadanne forbindelser Download PDFInfo
- Publication number
- DK595483A DK595483A DK595483A DK595483A DK595483A DK 595483 A DK595483 A DK 595483A DK 595483 A DK595483 A DK 595483A DK 595483 A DK595483 A DK 595483A DK 595483 A DK595483 A DK 595483A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- compounds
- imidazotriazines
- imidazopyrazines
- procedures
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000005235 imidazopyrazines Chemical class 0.000 title 1
- 150000005232 imidazopyridines Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- -1 C1-C4 Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000000229 (C1-C4)alkoxy group Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
- 125000004768 (C1-C4) alkylsulfinyl group Chemical group 0.000 abstract 1
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005336 allyloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001057 ionotropic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45356582A | 1982-12-27 | 1982-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK595483D0 DK595483D0 (da) | 1983-12-23 |
| DK595483A true DK595483A (da) | 1984-06-28 |
Family
ID=23801082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK595483A DK595483A (da) | 1982-12-27 | 1983-12-23 | Substituerede imidazopyridiner, imidazopyraziner og imidazotriaziner og fremgangsmaade til fremstilling af saadanne forbindelser |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0113236B1 (da) |
| JP (1) | JPS59130886A (da) |
| KR (1) | KR840007003A (da) |
| AT (1) | ATE26719T1 (da) |
| AU (1) | AU2288383A (da) |
| CA (1) | CA1262460A (da) |
| CS (1) | CS997783A2 (da) |
| DD (1) | DD210689A5 (da) |
| DE (1) | DE3371081D1 (da) |
| DK (1) | DK595483A (da) |
| ES (1) | ES528275A0 (da) |
| FI (1) | FI834773A7 (da) |
| GB (1) | GB2132203B (da) |
| GR (1) | GR81509B (da) |
| IL (1) | IL70495A0 (da) |
| NZ (1) | NZ206622A (da) |
| PL (1) | PL245275A1 (da) |
| PT (1) | PT77844B (da) |
| RO (1) | RO87859B (da) |
| SU (1) | SU1255052A3 (da) |
| ZA (1) | ZA839398B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MC1673A1 (fr) * | 1984-06-27 | 1986-06-03 | Wellcome Found | Derives aryliques de composes imidazoliques,leur preparation et leur emploi pour la preparation des medicaments |
| DE3446812A1 (de) * | 1984-12-21 | 1986-06-26 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| DE3446778A1 (de) * | 1984-12-21 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| US20110065728A1 (en) | 2008-05-14 | 2011-03-17 | Otsuka Pharmaceutical Factory, Inc. | Lipoprotein lipase-activating compositions comprising benzene derivatives |
| IN2012DN04917A (da) * | 2009-11-05 | 2015-09-25 | Univ Notre Dame Du Lac |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1026321B (de) * | 1955-05-26 | 1958-03-20 | Ind Chimica Profarmaco S R L | Verfahren zur Herstellung von (2, 3, 2', 3')-Imidazol-1, 2, 4-triazinen |
| GB1442707A (en) * | 1973-07-07 | 1976-07-14 | Yoshitomi Pharmaceutical | Substituted phenylalkanoic acids and their derivatives and pharma ceutical compositions thereof |
| US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
| US4151210A (en) * | 1977-06-23 | 1979-04-24 | Ciba-Geigy Corporation | Process for the production of phenylalkyl sulphones |
| DE2923602A1 (de) * | 1978-06-23 | 1980-01-10 | Sandoz Ag | Verwendung von substituierten alkylarylsulfoxiden und phenylarylsulfoxiden als photoinitiatoren |
| FR2502622A1 (fr) * | 1981-03-25 | 1982-10-01 | Synthelabo | Derives d'imidazo (1,2-a) pyrimidines, leur preparation et leur application en therapeutique |
| FR2510576A1 (fr) * | 1981-07-29 | 1983-02-04 | Synthelabo | Derives de phenyl-2 imidazo (1,2-a) pyrimidine, leur preparation et leur application en therapeutique |
-
1983
- 1983-12-19 PT PT77844A patent/PT77844B/pt unknown
- 1983-12-19 NZ NZ206622A patent/NZ206622A/en unknown
- 1983-12-19 ZA ZA839398A patent/ZA839398B/xx unknown
- 1983-12-19 RO RO112929A patent/RO87859B/ro unknown
- 1983-12-20 GR GR73288A patent/GR81509B/el unknown
- 1983-12-20 CA CA000443849A patent/CA1262460A/en not_active Expired
- 1983-12-20 IL IL70495A patent/IL70495A0/xx unknown
- 1983-12-21 EP EP83307816A patent/EP0113236B1/en not_active Expired
- 1983-12-21 GB GB08334096A patent/GB2132203B/en not_active Expired
- 1983-12-21 AT AT83307816T patent/ATE26719T1/de not_active IP Right Cessation
- 1983-12-21 ES ES528275A patent/ES528275A0/es active Granted
- 1983-12-21 DE DE8383307816T patent/DE3371081D1/de not_active Expired
- 1983-12-22 DD DD83258473A patent/DD210689A5/de unknown
- 1983-12-22 PL PL24527583A patent/PL245275A1/xx unknown
- 1983-12-23 AU AU22883/83A patent/AU2288383A/en not_active Abandoned
- 1983-12-23 DK DK595483A patent/DK595483A/da not_active Application Discontinuation
- 1983-12-23 FI FI834773A patent/FI834773A7/fi not_active Application Discontinuation
- 1983-12-26 SU SU833679907A patent/SU1255052A3/ru active
- 1983-12-26 KR KR1019830006176A patent/KR840007003A/ko not_active Ceased
- 1983-12-27 CS CS839977A patent/CS997783A2/cs unknown
- 1983-12-27 JP JP58252289A patent/JPS59130886A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK595483D0 (da) | 1983-12-23 |
| ATE26719T1 (de) | 1987-05-15 |
| FI834773A7 (fi) | 1984-06-28 |
| GB8334096D0 (en) | 1984-02-01 |
| ES8506712A1 (es) | 1985-08-01 |
| GB2132203B (en) | 1986-04-09 |
| EP0113236B1 (en) | 1987-04-22 |
| DD210689A5 (de) | 1984-06-20 |
| IL70495A0 (en) | 1984-03-30 |
| AU2288383A (en) | 1984-07-05 |
| FI834773A0 (fi) | 1983-12-23 |
| ES528275A0 (es) | 1985-08-01 |
| DE3371081D1 (en) | 1987-05-27 |
| PT77844A (en) | 1984-01-01 |
| RO87859B (ro) | 1985-12-31 |
| ZA839398B (en) | 1985-08-28 |
| RO87859A (ro) | 1985-12-30 |
| NZ206622A (en) | 1986-03-14 |
| GB2132203A (en) | 1984-07-04 |
| CS997783A2 (en) | 1985-06-13 |
| SU1255052A3 (ru) | 1986-08-30 |
| PL245275A1 (en) | 1985-03-26 |
| CA1262460A (en) | 1989-10-24 |
| PT77844B (en) | 1986-05-08 |
| GR81509B (da) | 1984-12-11 |
| KR840007003A (ko) | 1984-12-04 |
| JPS59130886A (ja) | 1984-07-27 |
| EP0113236A1 (en) | 1984-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |