DK596583D0 - 7-oxabicycloheptan-substituerede amino-prostaglandinanaloge - Google Patents

7-oxabicycloheptan-substituerede amino-prostaglandinanaloge

Info

Publication number
DK596583D0
DK596583D0 DK5965/83A DK596583A DK596583D0 DK 596583 D0 DK596583 D0 DK 596583D0 DK 5965/83 A DK5965/83 A DK 5965/83A DK 596583 A DK596583 A DK 596583A DK 596583 D0 DK596583 D0 DK 596583D0
Authority
DK
Denmark
Prior art keywords
oxabicycloheptan
substituted amino
prostaglandin analogue
prostaglandin
analogue
Prior art date
Application number
DK5965/83A
Other languages
English (en)
Other versions
DK596583A (da
Inventor
Martin Frederick Haslanger
Masami Nakane
Steven Edward Hall
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DK596583D0 publication Critical patent/DK596583D0/da
Publication of DK596583A publication Critical patent/DK596583A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK596583A 1982-12-27 1983-12-23 7-oxabicycloheptan-substituerede amino-prostaglandinanaloge DK596583A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/453,849 US4456616A (en) 1982-12-27 1982-12-27 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction

Publications (2)

Publication Number Publication Date
DK596583D0 true DK596583D0 (da) 1983-12-23
DK596583A DK596583A (da) 1984-06-28

Family

ID=23802327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK596583A DK596583A (da) 1982-12-27 1983-12-23 7-oxabicycloheptan-substituerede amino-prostaglandinanaloge

Country Status (17)

Country Link
US (1) US4456616A (da)
JP (1) JPS59122491A (da)
AU (1) AU558875B2 (da)
BE (1) BE898524A (da)
CA (1) CA1192567A (da)
CH (1) CH658659A5 (da)
DE (1) DE3346047A1 (da)
DK (1) DK596583A (da)
FR (1) FR2538390B1 (da)
GB (1) GB2132199B (da)
HU (1) HU190651B (da)
IE (1) IE56484B1 (da)
IT (1) IT1205309B (da)
LU (1) LU85149A1 (da)
NL (1) NL8304404A (da)
SE (1) SE454697B (da)
ZA (1) ZA839159B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537981A (en) * 1981-11-09 1985-08-27 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene compounds
US4533673A (en) * 1984-01-26 1985-08-06 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted enaminone prostaglandin analogs and their use in treatment of thrombolytic disease
US4526901A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxamide prostaglandin analogs and their use in treating thrombolytic disease
US4542156A (en) * 1984-04-26 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted prostaglandin alcohols and their use in the treatment of thrombolytic disease
US4550120A (en) * 1984-04-30 1985-10-29 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted ethers and their use in treating thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4639461A (en) * 1985-10-28 1987-01-27 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease
NZ218115A (en) * 1985-11-18 1990-02-26 Shionogi & Co Bicyclic sulphonamides and pharmaceutical compositions
JP2984077B2 (ja) * 1990-04-19 1999-11-29 塩野義製薬株式会社 スルホニルアミノ置換ビシクロ環系ヒドロキサム酸誘導体
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
US7915316B2 (en) * 2005-08-22 2011-03-29 Allergan, Inc Sulfonamides
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4239778A (en) * 1978-09-12 1980-12-16 The University Of Illinois Foundation Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation
EP0045118B1 (en) * 1979-01-05 1984-04-04 National Research Development Corporation Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
US4335537A (en) * 1979-11-28 1982-06-22 Plectrum Pty. Limited Toy aircraft
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
SE454697B (sv) 1988-05-24
GB2132199A (en) 1984-07-04
GB8333192D0 (en) 1984-01-18
IT1205309B (it) 1989-03-15
HU190651B (en) 1986-10-28
US4456616A (en) 1984-06-26
BE898524A (fr) 1984-06-22
LU85149A1 (fr) 1984-10-22
JPS59122491A (ja) 1984-07-14
SE8307146L (sv) 1984-06-28
AU558875B2 (en) 1987-02-12
AU2239883A (en) 1984-07-05
ZA839159B (en) 1984-07-25
GB2132199B (en) 1986-03-26
FR2538390B1 (fr) 1986-10-03
DE3346047A1 (de) 1984-06-28
CH658659A5 (fr) 1986-11-28
DK596583A (da) 1984-06-28
IT8324352A0 (it) 1983-12-23
CA1192567A (en) 1985-08-27
IE832998L (en) 1984-06-27
IE56484B1 (en) 1991-08-14
SE8307146D0 (sv) 1983-12-23
NL8304404A (nl) 1984-07-16
FR2538390A1 (fr) 1984-06-29

Similar Documents

Publication Publication Date Title
FI830924L (fi) Reaktionssystem i fluidiserad baedd
FI833088L (fi) Avslipande agglomerat foer anvaendning i skurande tvaettblandningar
FI833550A0 (fi) Luftstyrlaoda foer torkdelen i en pappersmaskin
FI821531A0 (fi) Formningssko foer formare i pappersmaskin
FI833103A7 (fi) Styranordning foer transportoer i en hanteringsanlaeggning foer glasskivor
FI821875L (fi) Matningsfoerraod foer borrstaenger i en laonghaolsborranordning
FI820776L (fi) Pressparti i pappersmaskin
DK596583A (da) 7-oxabicycloheptan-substituerede amino-prostaglandinanaloge
FI832759A0 (fi) Foerfarande foer datuminstaellning i en elektroniskt styrd frankeringsmaskin
FI821747A0 (fi) Smoerjsystem foer en borrstaongsnacke i en slagborrmaskin
FI823900A0 (fi) Regler/brandspjaell foer kanaler i ventilationsanlaeggningar
DK255083A (da) Substituerede pyridyl-phenyl-ethere
FI832790A7 (fi) Regleringsanordning foer oeppningen i en ljusbaoge foer glassmaeltningsugn
FI833654A7 (fi) Automatiskt styrsystem foer foerspaenningen i bildroer kompenserad foer olikheter i ledningsfoermaobildroerets elektronkanon
FI821737A0 (fi) Styrning foer en borrstaong i en borrmaskin
FI834128L (fi) Matningskrets ingaoende i en likstroemsmagnetiserad gaffeltransformator
FI824088A0 (fi) Nedloppskonstruktion foer kylare i roterugn
FI833290L (fi) Vattenhaltig tvaettmedelsblandning i vaetskeform
DE3374006D1 (de) Substituted 4-fluoropyridaz-6-ones
FI833653A7 (fi) Signalbehandlingskrets foer automatiskt foerspaenningsregleringssystem i bildroer
FI821902A0 (fi) Prisangivningssystem foer varor i foersaeljningsbord
FI823822A0 (fi) Bearbetningsbett foer en haolrotor i en barkningsmaskin
FI824243A0 (fi) Lastutrymme i fordon
IT8221572A1 (it) Tetratirochinoline sostituite
FI65678B (fi) Lokaliseringsanordning foer en kaelke i en faergnyanseringsmaskin