DK597083A - 16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling - Google Patents

16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling Download PDF

Info

Publication number: DK597083A
Authority: DK; Denmark
Prior art keywords: sub; ketoandrosten; dithioketals; procedure; preparation
Prior art date: 1982-12-27

Application number

DK597083A

Other languages

English (en)

Other versions

DK597083D0 (da

Inventor

Ravi K Varma

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-12-27

Filing date

1983-12-23

Publication date

1984-06-28

1983-12-23 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1983-12-23 Publication of DK597083D0 publication Critical patent/DK597083D0/da

1984-06-28 Publication of DK597083A publication Critical patent/DK597083A/da

Links

229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/04—Thiosulfonates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Steroid Compounds (AREA)
Dental Preparations (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK597083A 1982-12-27 1983-12-23 16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling DK597083A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/453,314 US4420428A (en)	1982-12-27	1982-12-27	16-Ketoandrostene-17-dithioketals

Publications (2)

Publication Number	Publication Date
DK597083D0 DK597083D0 (da)	1983-12-23
DK597083A true DK597083A (da)	1984-06-28

Family

ID=23800054

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK597083A DK597083A (da)	1982-12-27	1983-12-23	16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling

Country Status (10)

Country	Link
US (1)	US4420428A (da)
EP (1)	EP0112758B1 (da)
JP (1)	JPS59122500A (da)
AT (1)	ATE21518T1 (da)
CA (1)	CA1205462A (da)
DE (1)	DE3365482D1 (da)
DK (1)	DK597083A (da)
HU (1)	HU187099B (da)
IE (1)	IE56420B1 (da)
ZA (1)	ZA839077B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4427592A (en) *	1983-01-31	1984-01-24	E. R. Squibb & Sons, Inc.	Androstene-17-dithioketals
US4499021A (en) *	1984-04-12	1985-02-12	E. R. Squibb & Sons, Inc.	17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) *	1984-05-07	1985-07-16	E. R. Squibb & Sons, Inc.	17β-(substituted thio)androstenes
US4528138A (en) *	1984-06-20	1985-07-09	E. R. Squibb & Sons, Inc.	16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4891367A (en) *	1987-04-22	1990-01-02	Merrell Dow Pharmaceuticals Inc.	17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
CN1245982C (zh)	1996-05-09	2006-03-22	阿姆瑞德手术有限公司	哮喘和气道疾病的治疗
AU725048B2 (en) *	1996-05-09	2000-10-05	Amrad Operations Pty. Limited	Treatment of asthma and airway diseases
CN114790157B (zh) *	2022-02-28	2024-06-21	开封大地农化生物科技有限公司	一种高含量乙蒜素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4094840A (en) *	1977-05-12	1978-06-13	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) *	1977-05-12	1978-05-23	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) *	1978-02-17	1979-01-09	E. R. Squibb & Sons, Inc.	13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) *	1978-02-27	1979-03-27	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4252733A (en) *	1980-03-31	1981-02-24	E. R. Squibb & Sons, Inc.	17-Substituted sulfonyl-16,16-disubstituted androstenes
US4361559A (en) *	1981-08-20	1982-11-30	E. R. Squibb & Sons, Inc.	Antiinflammatory 17,17-bis (substituted thio) androstenes

1982
- 1982-12-27 US US06/453,314 patent/US4420428A/en not_active Expired - Fee Related
1983
- 1983-12-05 CA CA000442554A patent/CA1205462A/en not_active Expired
- 1983-12-06 ZA ZA839077A patent/ZA839077B/xx unknown
- 1983-12-08 AT AT83402376T patent/ATE21518T1/de not_active IP Right Cessation
- 1983-12-08 DE DE8383402376T patent/DE3365482D1/de not_active Expired
- 1983-12-08 EP EP83402376A patent/EP0112758B1/en not_active Expired
- 1983-12-20 IE IE2999/83A patent/IE56420B1/en not_active IP Right Cessation
- 1983-12-20 JP JP58241791A patent/JPS59122500A/ja active Pending
- 1983-12-23 DK DK597083A patent/DK597083A/da not_active Application Discontinuation
- 1983-12-27 HU HU834479A patent/HU187099B/hu unknown

Also Published As

Publication number	Publication date
JPS59122500A (ja)	1984-07-14
ZA839077B (en)	1984-07-25
DK597083D0 (da)	1983-12-23
HU187099B (en)	1985-11-28
CA1205462A (en)	1986-06-03
EP0112758B1 (en)	1986-08-20
US4420428A (en)	1983-12-13
ATE21518T1 (de)	1986-09-15
IE832999L (en)	1984-06-27
IE56420B1 (en)	1991-07-31
EP0112758A1 (en)	1984-07-04
DE3365482D1 (de)	1986-09-25

Similar Documents

Publication	Publication Date	Title
DK550188A (da)	1989-04-02	Antigestagen- og antioestrogenvirksomme forbindelser til behandling af hormonafhaengige tumorer
NO862753D0 (no)	1986-07-08	Fremgangsmaate for fremstilling av andosta-1,4-diene-3,17-dioner.
ES514633A0 (es)	1983-06-16	"metodo de preparar compuestos esteroidicos antiinflamatorios".
DK597083A (da)	1984-06-28	16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling
ES524796A0 (es)	1984-05-01	Procedimiento de preparacion de nuevos derivos de amino-14 esteroides
AU518080B2 (en)	1981-09-10	Primary choke system
JPS57106700A (en)	1982-07-02	Novel 17-oxazoline steroid derivatives, manufacture and use for manufacture of corticosteroid
NO901102D0 (no)	1990-03-08	Fremgangsmaate for fremstilling av nye steroidderivater.
DK595383A (da)	1984-06-28	C-3''-alkylerede oleandomycin-derivater og 10- og 4''-epi-derivater deraf samt fremgangsmaade til fremstilling deraf
AU529292B2 (en)	1983-06-02	17-substituted pregnane steroids
JPS56152499A (en)	1981-11-26	17-substituted sulfonyl-16,16-disubstituted androstene derivative
AU5713280A (en)	1980-09-18	Steroid immunogens
IE782486L (en)	1979-06-19	Manufacture of pregnane derivative.
IT7852164A0 (it)	1978-12-01	Procedimento per la preparazione di 3-osso-4,6-dieni steroidici
AU7828381A (en)	1982-06-10	Derivatives of estra 4,9-diene
AU540003B2 (en)	1984-10-25	Fixation loop for transvenous leads
FI875322A7 (fi)	1987-12-02	Menetelmä 17a -hydroksi-D-homo-1,4 -pregnadieeni-3,20-dionin valmista miseksi.
AU532331B2 (en)	1983-09-29	3-hydroxy-1,4-benzodiazepine-2-ones
AU3990178A (en)	1980-03-20	Pregnane derivatives
AU7772381A (en)	1982-05-27	3-amino substituted steroid derivatives
NO873567L (no)	1986-10-06	Fremgangsmaate for fremstilling av steroidforbindelser.
IT8454223V0 (it)	1984-12-24	Introduttore per suppositori
AU535046B2 (en)	1984-03-01	Amino-14 steroid derivatives
BA97185B1 (bs)	1999-08-02	Postupak za dobijanje supstituisanih androsta-1,4-dien-3,17-diona
AU482508B2 (en)	1976-09-02	Steroid derivatives

Legal Events

Date	Code	Title	Description
1991-03-18	AHS	Application shelved for other reasons than non-payment