DK60586A - Inhibin isoleret fra ovariefollikelvaeske og fremgangsmaade til isolering og rensning af inhibin - Google Patents

Inhibin isoleret fra ovariefollikelvaeske og fremgangsmaade til isolering og rensning af inhibin Download PDF

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Publication number
DK60586A
DK60586A DK60586A DK60586A DK60586A DK 60586 A DK60586 A DK 60586A DK 60586 A DK60586 A DK 60586A DK 60586 A DK60586 A DK 60586A DK 60586 A DK60586 A DK 60586A
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DK
Denmark
Prior art keywords
inhibin
protein
purified
steps
subunits
Prior art date
Application number
DK60586A
Other languages
English (en)
Other versions
DK171711B1 (da
DK60586D0 (da
Inventor
David Moritz De Kretser
Milton Thomas William Hearn
Henry George Burger
John Kerr Findlay
Francis Joseph Morgan
David Mark Robertson
Robert Gregory Forage
Original Assignee
Univ Monash
Prince Henrys Hospital
St Vincents Inst Med Res
Biotech Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Monash, Prince Henrys Hospital, St Vincents Inst Med Res, Biotech Australia Pty Ltd filed Critical Univ Monash
Publication of DK60586A publication Critical patent/DK60586A/da
Publication of DK60586D0 publication Critical patent/DK60586D0/da
Application granted granted Critical
Publication of DK171711B1 publication Critical patent/DK171711B1/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Networks Using Active Elements (AREA)
  • Centrifugal Separators (AREA)
  • External Artificial Organs (AREA)
DK060586A 1984-06-08 1986-02-07 Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin DK171711B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AUPG542784 1984-06-08
AUPG542784 1984-06-08
AUPH003185 1985-04-04
AUPH003185 1985-04-04
AU8500119 1985-06-03
PCT/AU1985/000119 WO1986000078A1 (en) 1984-06-08 1985-06-03 Inhibin isolated from ovarian follicular fluid

Publications (3)

Publication Number Publication Date
DK60586A true DK60586A (da) 1986-02-07
DK60586D0 DK60586D0 (da) 1986-02-07
DK171711B1 DK171711B1 (da) 1997-04-01

Family

ID=25642809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK060586A DK171711B1 (da) 1984-06-08 1986-02-07 Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin

Country Status (10)

Country Link
US (2) US5102807A (da)
EP (1) EP0185034B1 (da)
JP (2) JP2521707B2 (da)
AT (1) ATE95194T1 (da)
CA (1) CA1341617C (da)
DE (1) DE3587603T2 (da)
DK (1) DK171711B1 (da)
NO (1) NO176570C (da)
NZ (1) NZ212248A (da)
WO (1) WO1986000078A1 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
KR940004077B1 (ko) * 1985-04-18 1994-05-11 바이오테크놀로지 오스트레일리아 프로프라이어터리 리밋티드 재조합 인히빈
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US5215893A (en) * 1985-10-03 1993-06-01 Genentech, Inc. Nucleic acid encoding the ba chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
NZ217727A (en) * 1985-10-03 1990-05-28 Genentech Inc Nucleic acid encoding alpha or b chain of inhibin, its production and compositions containing it
US5089396A (en) * 1985-10-03 1992-02-18 Genentech, Inc. Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
AU599373B2 (en) * 1986-03-13 1990-07-19 Biotechnology Australia Proprietary Limited Method of assay of inhibin
US5015729A (en) * 1986-06-24 1991-05-14 The Salk Institute For Biological Studies Ovine inhibin
US6150328A (en) * 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
DE3853383T2 (de) * 1987-01-29 1995-07-27 Biotech Australia Pty Ltd Isolierung von einkettigen proteinen mit fsh unter- drückender aktivität aus follikularflüssigkeit.
US5032507A (en) * 1987-11-13 1991-07-16 The Salk Institute For Biological Studies Potentiation of erythropoiesis
WO1989011862A1 (en) * 1988-05-31 1989-12-14 Biotechnology Australia Pty. Ltd. Actions of hormones
CA2069755A1 (en) * 1990-01-08 1991-07-09 Jennie P. Mather Method for increasing fertility in females
DE4000327A1 (de) * 1990-01-08 1991-07-11 Stefan Heiden Arzneimittel zur verbesserung der ovarreaktion und der eizell- und embryonen- produktion bei haussaeugetieren
US5942220A (en) * 1990-03-16 1999-08-24 Chiron Corporation Inhibitor of cytokine activity and applications thereof
US20080139474A1 (en) * 1991-11-04 2008-06-12 David Israel Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
WO1993009229A1 (en) 1991-11-04 1993-05-13 Genetics Institute, Inc. Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
US5428011A (en) * 1992-06-16 1995-06-27 Procyon Biopharma, Inc. Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma
WO1994026892A1 (en) * 1993-05-12 1994-11-24 Genetics Institute, Inc. Bmp-11 compositions
US6291206B1 (en) * 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
AU689184B2 (en) * 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
US20030171283A1 (en) * 1994-02-28 2003-09-11 Satterlee Daniel G. Inhibin compositions and methods of enhancing production performance
US5725858A (en) * 1994-02-28 1998-03-10 Agritech Technologies, Ltd. Methods of enhancing production performance of birds comprising administration of heterologous protein comprising avian alpha-subunit inhibin protein
US5786179A (en) * 1994-02-28 1998-07-28 Agritech Technologies Ltd. Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same
AUPO638897A0 (en) * 1997-04-23 1997-05-22 Monash University Modulation of cell growth and methods relating thereto
AU780982B2 (en) * 1997-04-23 2005-04-28 Monash University Inhibin modulation of cell growth
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DK1223990T3 (da) 1999-10-15 2004-11-29 Inst Genetics Llc Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner
CA2355334A1 (en) * 2000-10-16 2002-04-16 Procyon Biopharma Inc. Pharmaceutical preparations and methods for inhibiting tumors
US20030082233A1 (en) * 2000-12-01 2003-05-01 Lyons Karen M. Method and composition for modulating bone growth
TW200526779A (en) * 2001-02-08 2005-08-16 Wyeth Corp Modified and stabilized GDF propeptides and uses thereof
US7226587B2 (en) * 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en) * 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20050026833A1 (en) * 2001-11-08 2005-02-03 Rabbani Shafaat Ahmed PSP-94: use for treatment of hypercalcemia and bone metastasis
TWI282283B (en) * 2002-05-17 2007-06-11 Wyeth Corp Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
AU2003297254A1 (en) * 2002-11-07 2004-06-03 Agritech Technology, Ltd Novel compositions that enhance production performance in avians
JP5392981B2 (ja) * 2003-09-12 2014-01-22 ワイス・エルエルシー 骨形成蛋白の送達のための注入可能なリン酸カルシウム固体ロッドおよびペースト
US9651565B2 (en) 2010-11-29 2017-05-16 Mote Marine Laboratory, Inc. Fish sexual characteristic determination using peptide hormones
BR102014005376A2 (pt) * 2014-03-07 2016-02-10 Ouro Fino Saúde Animal Ltda antígeno de inibina alfa, gene codificante de inibina alfa, gene codificante de proteína de fusão, processo de obtenção do antígeno de inibina alfa, composição antigênica, uso do antígeno de inibina alfa e uso da composição antigênica

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
CA1007568A (en) * 1973-12-13 1977-03-29 Canada Packers Limited Bovine immunoglobulin isolation process
FR2361912A1 (fr) * 1976-08-19 1978-03-17 Merck & Co Inc Vaccin anti-fecondite a base de membrane pellucide solubilisee
US4409139A (en) * 1981-08-10 1983-10-11 The Salk Institute For Biological Studies Gonadostatin
US4423037A (en) * 1982-05-13 1983-12-27 The General Hospital Corporation Inhibitors of peptide hormone action
CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
KR940004077B1 (ko) * 1985-04-18 1994-05-11 바이오테크놀로지 오스트레일리아 프로프라이어터리 리밋티드 재조합 인히빈
US4624944A (en) * 1985-06-14 1986-11-25 The Regents Of The University Of California Human seminal alpha-inhibins
US4740587A (en) * 1985-07-18 1988-04-26 The Salk Institute For Biological Studies Inhibin and method of purifying same
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
US4737578A (en) * 1986-02-10 1988-04-12 The Salk Institute For Biological Studies Human inhibin
WO1989011862A1 (en) * 1988-05-31 1989-12-14 Biotechnology Australia Pty. Ltd. Actions of hormones

Also Published As

Publication number Publication date
NZ212248A (en) 1991-05-28
CA1341617C (en) 2011-06-28
EP0185034B1 (en) 1993-09-29
EP0185034A4 (da) 1988-01-28
DK171711B1 (da) 1997-04-01
NO860427L (no) 1986-02-06
DE3587603T2 (de) 1994-02-10
DE3587603D1 (de) 1993-11-04
JPS61502399A (ja) 1986-10-23
US5364837A (en) 1994-11-15
DK60586D0 (da) 1986-02-07
ATE95194T1 (de) 1993-10-15
EP0185034A1 (da) 1986-06-25
JP2583030B2 (ja) 1997-02-19
WO1986000078A1 (en) 1986-01-03
US5102807A (en) 1992-04-07
JP2521707B2 (ja) 1996-08-07
NO176570B (no) 1995-01-16
NO176570C (no) 1995-04-26
JPH0848636A (ja) 1996-02-20

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Legal Events

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AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PUP Patent expired