DK606088A - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase - Google Patents
Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetaseInfo
- Publication number
- DK606088A DK606088A DK606088A DK606088A DK606088A DK 606088 A DK606088 A DK 606088A DK 606088 A DK606088 A DK 606088A DK 606088 A DK606088 A DK 606088A DK 606088 A DK606088 A DK 606088A
- Authority
- DK
- Denmark
- Prior art keywords
- isopenicillin
- synthetase
- coding
- expression vectors
- dna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/115,950 US4950603A (en) | 1987-11-02 | 1987-11-02 | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from Streptomyces lipmanii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK606088D0 DK606088D0 (da) | 1988-10-31 |
| DK606088A true DK606088A (da) | 1989-06-15 |
Family
ID=22364332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK606088A DK606088A (da) | 1987-11-02 | 1988-10-31 | Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4950603A (de) |
| EP (1) | EP0317096A3 (de) |
| AU (1) | AU611727B2 (de) |
| DK (1) | DK606088A (de) |
| HU (1) | HU204091B (de) |
| IL (1) | IL88171A0 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI104264B (fi) * | 1988-08-11 | 1999-12-15 | Dsm Ip Assets Bv | Menetelmä sekundääristen metaboliittien tuoton parantamiseksi käyttämällä rykelmöityjä biosynteettisiä geenejä |
| US5589385A (en) * | 1990-07-26 | 1996-12-31 | American Cyanamid Company | Cloning of the biosynthetic pathway for chlortetracycline and tetracycline formation and cosmids useful therein |
| GB9621486D0 (en) * | 1996-10-15 | 1996-12-04 | Isis Innovation | Oxygenase enzymes & method |
| US6284483B1 (en) * | 1999-10-06 | 2001-09-04 | Board Of Trustees Operating Michigan State University | Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate |
| US9637746B2 (en) | 2008-12-15 | 2017-05-02 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways |
| CN105132387A (zh) * | 2008-12-22 | 2015-12-09 | 绿光生物科学公司 | 用于制造化合物的组合物和方法 |
| EP2566953B1 (de) | 2010-05-07 | 2019-01-02 | Greenlight Biosciences, Inc. | Verfahren zur flusssteuerung bei stoffwechselwegen druch enzymumpositionierung |
| EP2611922A1 (de) | 2010-08-31 | 2013-07-10 | Greenlight Biosciences, Inc. | Verfahren zur flusssteuerung bei stoffwechselwegen durch proteasemanipulation |
| CN104093848A (zh) | 2011-09-09 | 2014-10-08 | 绿光生物科学公司 | 碳青霉烯(carbapenem)的无细胞制备 |
| AU2014306074B2 (en) | 2013-08-05 | 2018-08-30 | Greenlight Biosciences, Inc. | Engineered proteins with a protease cleavage site |
| BR112017020690A2 (pt) | 2015-03-30 | 2018-06-26 | Greenlight Biosciences Inc | produção livre de células de ácido ribonucleico |
| CA3020312A1 (en) | 2016-04-06 | 2017-10-12 | Greenlight Biosciences, Inc. | Cell-free production of ribonucleic acid |
| KR102894284B1 (ko) | 2017-10-11 | 2025-12-03 | 그린라이트 바이오사이언시스, 아이엔씨. | 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU1780542C (ru) * | 1985-04-22 | 1992-12-07 | Эли Лилли Энд Компани | Способ конструировани рекомбинантной плазмидной ДНК pPS 20, кодирующей изопенициллин-N-синтетазу, способ получени штамма СернаLоSроRIUм асRемоNIUм, обладающего активностью изопенициллин-N-синтетазы |
| IL78531A0 (en) * | 1985-04-22 | 1986-08-31 | Lilly Co Eli | Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase |
| US4892819A (en) * | 1985-11-25 | 1990-01-09 | Eli Lilly And Company | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum |
| DE3789880T2 (de) * | 1986-01-31 | 1994-09-08 | Beecham Group Plc | Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen. |
| EP0303364A1 (de) * | 1987-08-10 | 1989-02-15 | The Governors of the University of Alberta | Klonierung und Bestimmung der Nukleotidesequenz vom Gen isopenicillin-N-synthetase aus Streptomyces clavuligerus |
| US4885252A (en) * | 1987-09-08 | 1989-12-05 | Eli Lilly And Company | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans |
-
1987
- 1987-11-02 US US07/115,950 patent/US4950603A/en not_active Expired - Fee Related
-
1988
- 1988-10-26 IL IL88171A patent/IL88171A0/xx unknown
- 1988-10-27 EP EP88310084A patent/EP0317096A3/de not_active Ceased
- 1988-10-31 AU AU24551/88A patent/AU611727B2/en not_active Ceased
- 1988-10-31 DK DK606088A patent/DK606088A/da not_active Application Discontinuation
- 1988-11-01 HU HU885665A patent/HU204091B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4950603A (en) | 1990-08-21 |
| DK606088D0 (da) | 1988-10-31 |
| IL88171A0 (en) | 1989-06-30 |
| EP0317096A2 (de) | 1989-05-24 |
| HU204091B (en) | 1991-11-28 |
| AU2455188A (en) | 1989-05-25 |
| AU611727B2 (en) | 1991-06-20 |
| EP0317096A3 (de) | 1989-11-23 |
| HUT50508A (en) | 1990-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |