DK606088D0 - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase - Google Patents
Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetaseInfo
- Publication number
- DK606088D0 DK606088D0 DK606088A DK606088A DK606088D0 DK 606088 D0 DK606088 D0 DK 606088D0 DK 606088 A DK606088 A DK 606088A DK 606088 A DK606088 A DK 606088A DK 606088 D0 DK606088 D0 DK 606088D0
- Authority
- DK
- Denmark
- Prior art keywords
- isopenicillin
- synthetase
- coding
- expression vectors
- dna
- Prior art date
Links
- 108020004414 DNA Proteins 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000013604 expression vector Substances 0.000 title 1
- 108010012172 isopenicillin N synthetase Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/115,950 US4950603A (en) | 1987-11-02 | 1987-11-02 | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from Streptomyces lipmanii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK606088D0 true DK606088D0 (da) | 1988-10-31 |
| DK606088A DK606088A (da) | 1989-06-15 |
Family
ID=22364332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK606088A DK606088A (da) | 1987-11-02 | 1988-10-31 | Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4950603A (da) |
| EP (1) | EP0317096A3 (da) |
| AU (1) | AU611727B2 (da) |
| DK (1) | DK606088A (da) |
| HU (1) | HU204091B (da) |
| IL (1) | IL88171A0 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI104264B (fi) * | 1988-08-11 | 1999-12-15 | Dsm Ip Assets Bv | Menetelmä sekundääristen metaboliittien tuoton parantamiseksi käyttämällä rykelmöityjä biosynteettisiä geenejä |
| US5589385A (en) * | 1990-07-26 | 1996-12-31 | American Cyanamid Company | Cloning of the biosynthetic pathway for chlortetracycline and tetracycline formation and cosmids useful therein |
| GB9621486D0 (en) * | 1996-10-15 | 1996-12-04 | Isis Innovation | Oxygenase enzymes & method |
| US6284483B1 (en) * | 1999-10-06 | 2001-09-04 | Board Of Trustees Operating Michigan State University | Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate |
| WO2010077806A1 (en) | 2008-12-15 | 2010-07-08 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways |
| CN102333878B (zh) * | 2008-12-22 | 2015-08-26 | 绿光生物科学公司 | 用于制造化合物的组合物和方法 |
| KR20130071433A (ko) | 2010-05-07 | 2013-06-28 | 그린라이트 바이오사이언시스, 아이엔씨. | 효소의 재배치를 통한 대사 경로에서의 흐름의 제어 방법 |
| US8916358B2 (en) | 2010-08-31 | 2014-12-23 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
| CN104093848A (zh) | 2011-09-09 | 2014-10-08 | 绿光生物科学公司 | 碳青霉烯(carbapenem)的无细胞制备 |
| WO2015021058A2 (en) | 2013-08-05 | 2015-02-12 | Greenlight Biosciences, Inc. | Engineered proteins with a protease cleavage site |
| RU2017137788A (ru) | 2015-03-30 | 2019-04-30 | Гринлайт Байосайенсис, Инк. | Бесклеточное получение рибонуклеиновой кислоты |
| SG11201808721YA (en) | 2016-04-06 | 2018-11-29 | Greenlight Biosciences Inc | Cell-free production of ribonucleic acid |
| WO2019075167A1 (en) | 2017-10-11 | 2019-04-18 | Greenlight Biosciences, Inc. | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF NUCLEOSIDE TRIPHOSPHATE AND RIBONUCLEIC ACID |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU1780542C (ru) * | 1985-04-22 | 1992-12-07 | Эли Лилли Энд Компани | Способ конструировани рекомбинантной плазмидной ДНК pPS 20, кодирующей изопенициллин-N-синтетазу, способ получени штамма СернаLоSроRIUм асRемоNIUм, обладающего активностью изопенициллин-N-синтетазы |
| CA1309673C (en) * | 1985-04-22 | 1992-11-03 | Stephen Wyatt Queener | Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase |
| US4892819A (en) * | 1985-11-25 | 1990-01-09 | Eli Lilly And Company | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum |
| EP0233715B1 (en) * | 1986-01-31 | 1994-05-25 | BEECHAM GROUP plc | Isolation and expression of genes involved in the biosynthesis of beta-lactams |
| EP0303364A1 (en) * | 1987-08-10 | 1989-02-15 | The Governors of the University of Alberta | Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from streptomyces clavuligerus |
| US4885252A (en) * | 1987-09-08 | 1989-12-05 | Eli Lilly And Company | Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans |
-
1987
- 1987-11-02 US US07/115,950 patent/US4950603A/en not_active Expired - Fee Related
-
1988
- 1988-10-26 IL IL88171A patent/IL88171A0/xx unknown
- 1988-10-27 EP EP88310084A patent/EP0317096A3/en not_active Ceased
- 1988-10-31 DK DK606088A patent/DK606088A/da not_active Application Discontinuation
- 1988-10-31 AU AU24551/88A patent/AU611727B2/en not_active Ceased
- 1988-11-01 HU HU885665A patent/HU204091B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU204091B (en) | 1991-11-28 |
| US4950603A (en) | 1990-08-21 |
| AU611727B2 (en) | 1991-06-20 |
| EP0317096A2 (en) | 1989-05-24 |
| DK606088A (da) | 1989-06-15 |
| AU2455188A (en) | 1989-05-25 |
| HUT50508A (en) | 1990-02-28 |
| IL88171A0 (en) | 1989-06-30 |
| EP0317096A3 (en) | 1989-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |