DK608089A - Antiviralt middel - Google Patents

Antiviralt middel Download PDF

Info

Publication number: DK608089A
Authority: DK; Denmark
Prior art keywords: rna; bioparyl; flavopereirine; primers; fragments
Prior art date: 1988-12-02

Application number

DK608089A

Other languages

Danish (da)

English (en)

Other versions

DK608089D0 (da

Inventor

Mirko Beljanski

Original Assignee

Fondation Encourag Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-02

Filing date

1989-12-01

Publication date

1990-06-03

1989-12-01 Application filed by Fondation Encourag Rech Med filed Critical Fondation Encourag Rech Med

1989-12-01 Publication of DK608089D0 publication Critical patent/DK608089D0/da

1990-06-03 Publication of DK608089A publication Critical patent/DK608089A/da

Links

239000003443 antiviral agent Substances 0.000 title 1
MGHKUXYLAVTETL-UHFFFAOYSA-N 3-ethyl-12h-indolo[2,3-a]quinolizin-5-ium;chloride Chemical compound [Cl-].N1C2=CC=CC=C2C2=C1C1=CC=C(CC)C=[N+]1C=C2 MGHKUXYLAVTETL-UHFFFAOYSA-N 0.000 abstract 2
BAALMEGRQMMBJQ-UHFFFAOYSA-N Flavopereirine Natural products N1=C2C=CC=CC2=C2C1=C1C=CC(CC)=CN1C=C2 BAALMEGRQMMBJQ-UHFFFAOYSA-N 0.000 abstract 2
239000012634 fragment Substances 0.000 abstract 2
FTVWIRXFELQLPI-ZDUSSCGKSA-N (S)-naringenin Chemical compound C1=CC(O)=CC=C1[C@H]1OC2=CC(O)=CC(O)=C2C(=O)C1 FTVWIRXFELQLPI-ZDUSSCGKSA-N 0.000 abstract 1
DAGPUIPHACXCSU-UHFFFAOYSA-O 3-ethyl-7,12-dihydro-6h-indolo[2,3-a]quinolizin-5-ium Chemical compound N1C2=CC=CC=C2C2=C1C1=CC=C(CC)C=[N+]1CC2 DAGPUIPHACXCSU-UHFFFAOYSA-O 0.000 abstract 1
239000001606 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one Substances 0.000 abstract 1
208000030507 AIDS Diseases 0.000 abstract 1
244000194101 Ginkgo biloba Species 0.000 abstract 1
239000013616 RNA primer Substances 0.000 abstract 1
229930013930 alkaloid Natural products 0.000 abstract 1
150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
WGEYAGZBLYNDFV-UHFFFAOYSA-N naringenin Natural products C1(=O)C2=C(O)C=C(O)C=C2OC(C1)C1=CC=C(CC1)O WGEYAGZBLYNDFV-UHFFFAOYSA-N 0.000 abstract 1
229940117954 naringenin Drugs 0.000 abstract 1
235000007625 naringenin Nutrition 0.000 abstract 1
DFPMSGMNTNDNHN-ZPHOTFPESA-N naringin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC=2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C=2C=CC(O)=CC=2)O[C@H](CO)[C@@H](O)[C@@H]1O DFPMSGMNTNDNHN-ZPHOTFPESA-N 0.000 abstract 1
229930019673 naringin Natural products 0.000 abstract 1
229940052490 naringin Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000013615 primer Substances 0.000 abstract 1
230000010076 replication Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
230000003612 virological effect Effects 0.000 abstract 1
AIFRHYZBTHREPW-UHFFFAOYSA-N β-carboline Chemical class N1=CC=C2C3=CC=CC=C3NC2=C1 AIFRHYZBTHREPW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Natural Medicines & Medicinal Plants (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Microbiology (AREA)
Immunology (AREA)
Virology (AREA)
Oncology (AREA)
Alternative & Traditional Medicine (AREA)
Biotechnology (AREA)
Botany (AREA)
Medical Informatics (AREA)
Bioinformatics & Cheminformatics (AREA)
Mycology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK608089A 1988-12-02 1989-12-01 Antiviralt middel DK608089A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8815845A FR2639830B1 (fr)	1988-12-02	1988-12-02	Composition antivirale et ses applications

Publications (2)

Publication Number	Publication Date
DK608089D0 DK608089D0 (da)	1989-12-01
DK608089A true DK608089A (da)	1990-06-03

Family

ID=9372531

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK608089A DK608089A (da)	1988-12-02	1989-12-01	Antiviralt middel

Country Status (8)

Country	Link
EP (1)	EP0373986B1 (ja)
JP (1)	JPH0737393B2 (ja)
AT (1)	ATE94072T1 (ja)
DE (1)	DE68909019T2 (ja)
DK (1)	DK608089A (ja)
ES (1)	ES2059803T3 (ja)
FR (1)	FR2639830B1 (ja)
IL (1)	IL92523A (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02270824A (ja) *	1989-04-13	1990-11-05	Snow Brand Milk Prod Co Ltd	逆転写酵素阻害剤
DE4105570A1 (de) *	1991-02-22	1992-08-27	Helmut Dr Med Scholle	Verwendung eines bakterien- und eiweissfreien filtrats
DE4208868A1 (de) *	1992-03-04	1993-09-09	Michaelis Peter Dr Med	Verwendung eines arzneimittels zur behandlung von metastatischen krebserkrankungen
FR2694693B1 (fr) *	1992-07-28	1994-10-28	Abrax Bio Labs Sa	Composition pharmaceutique à base de flavopéréirine et son utilisation dans un traitement contre le virus VIH.
DE4308443C2 (de) *	1993-03-17	1996-09-19	Laves Hans Georg	Arzneimittel zur Behandlung von Retrovirusinfektionen
JP2003504327A (ja)	1999-07-08	2003-02-04	プレンダーガスト、パトリック、ティ．	感染症の治療を目的としたフラボン類、クマリン類および関連化合物の使用
KR100417172B1 (ko) *	2000-08-04	2004-02-05	주식회사 안지오랩	은행엽 엑스를 유효성분으로 하는 혈관신생 억제제
EP1786519B1 (en) *	2004-05-19	2012-09-05	Natural Source International	Flavopereirine and alstonine combinations in the treatment and prevention of prostate cancer
CN107501224B (zh) *	2017-09-12	2021-01-19	临沂金卓生物科技有限公司	一种沸石分子筛催化水解银杏黄酮糖苷生产黄酮苷元的方法
CN112601527B (zh) *	2018-03-31	2024-12-31	分子国际研究公司	用于有效预防和治疗的选择性抗癌剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2450607A2 (fr) *	1978-03-13	1980-10-03	Beljanski Mirko	Composition pharmaceutique contenant comme principe actif la flavopereine
ATE15971T1 (de) *	1981-03-11	1985-10-15	Mirko Beljanski	Serpentin, alstonin und sempervirin, medikamente, die die tumor- und krebszellen spezifisch hemmen.

1988
- 1988-12-02 FR FR8815845A patent/FR2639830B1/fr not_active Expired - Lifetime
1989
- 1989-11-17 DE DE89403176T patent/DE68909019T2/de not_active Expired - Fee Related
- 1989-11-17 AT AT89403176T patent/ATE94072T1/de not_active IP Right Cessation
- 1989-11-17 ES ES89403176T patent/ES2059803T3/es not_active Expired - Lifetime
- 1989-11-17 EP EP89403176A patent/EP0373986B1/fr not_active Expired - Lifetime
- 1989-12-01 JP JP1310818A patent/JPH0737393B2/ja not_active Expired - Lifetime
- 1989-12-01 IL IL9252389A patent/IL92523A/en not_active IP Right Cessation
- 1989-12-01 DK DK608089A patent/DK608089A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK608089D0 (da)	1989-12-01
EP0373986B1 (fr)	1993-09-08
DE68909019T2 (de)	1994-03-17
ATE94072T1 (de)	1993-09-15
IL92523A0 (en)	1990-08-31
DE68909019D1 (de)	1993-10-14
JPH0737393B2 (ja)	1995-04-26
ES2059803T3 (es)	1994-11-16
FR2639830B1 (fr)	1991-03-22
FR2639830A1 (fr)	1990-06-08
EP0373986A1 (fr)	1990-06-20
JPH02184632A (ja)	1990-07-19
IL92523A (en)	1994-05-30

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Legal Events

Date	Code	Title	Description
2001-07-30	AHB	Application shelved due to non-payment