DK615789A - Fremgangsmaade til fotokemisk omdannelse af tachysterolforbindelser til prae-vitamin d forbindelser og af trans-vitamin d forbindelser til cis-vitamin d forbindelser - Google Patents

Fremgangsmaade til fotokemisk omdannelse af tachysterolforbindelser til prae-vitamin d forbindelser og af trans-vitamin d forbindelser til cis-vitamin d forbindelser Download PDF

Info

Publication number: DK615789A
Authority: DK; Denmark
Prior art keywords: compounds; vitamin; compound; cis; trans
Prior art date: 1988-12-12

Application number

DK615789A

Other languages

English (en)

Other versions

DK615789D0 (da

Inventor

Eric J Goethals

Sebastianus J Halkes

Robert B Koolstra

Original Assignee

Duphar Int Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-12

Filing date

1989-12-07

Publication date

1990-06-13

1989-12-07 Application filed by Duphar Int Res filed Critical Duphar Int Res

1989-12-07 Publication of DK615789D0 publication Critical patent/DK615789D0/da

1990-06-13 Publication of DK615789A publication Critical patent/DK615789A/da

Links

238000006243 chemical reaction Methods 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
XQFJZHAVTPYDIQ-LETJEVNCSA-N (1s)-3-[(e)-2-[(1r,3ar,7ar)-1-[(e,2r,5r)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-3-en-1-ol Chemical class C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)/C=C/[C@H](C)C(C)C)\C=C\C1=C(C)CC[C@H](O)C1 XQFJZHAVTPYDIQ-LETJEVNCSA-N 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 3
229940088594 vitamin Drugs 0.000 title 3
239000011782 vitamin Substances 0.000 title 3
229920000642 polymer Polymers 0.000 abstract 5
239000003504 photosensitizing agent Substances 0.000 abstract 4
239000011710 vitamin D Substances 0.000 abstract 4
229940046008 vitamin d Drugs 0.000 abstract 4
125000003277 amino group Chemical group 0.000 abstract 3
239000004721 Polyphenylene oxide Substances 0.000 abstract 2
229920000570 polyether Polymers 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
-1 tachysterol compound Chemical class 0.000 abstract 2
206010073306 Exposure to radiation Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229920001400 block copolymer Polymers 0.000 abstract 1
238000001816 cooling Methods 0.000 abstract 1
239000002244 precipitate Substances 0.000 abstract 1
YUGCAAVRZWBXEQ-WHTXLNIXSA-N previtamin D3 Chemical class C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)CCCC(C)C)\C=C/C1=C(C)CC[C@H](O)C1 YUGCAAVRZWBXEQ-WHTXLNIXSA-N 0.000 abstract 1
230000005855 radiation Effects 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
BUNBVCKYYMRTNS-UHFFFAOYSA-N tachysterol Natural products C=1CCC2(C)C(C(C)CCC(C)C(C)C)CCC2C=1C=CC1=C(C)CCC(O)C1 BUNBVCKYYMRTNS-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Polyethers (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

DK615789A 1988-12-12 1989-12-07 Fremgangsmaade til fotokemisk omdannelse af tachysterolforbindelser til prae-vitamin d forbindelser og af trans-vitamin d forbindelser til cis-vitamin d forbindelser DK615789A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8803040		1988-12-12

Publications (2)

Publication Number	Publication Date
DK615789D0 DK615789D0 (da)	1989-12-07
DK615789A true DK615789A (da)	1990-06-13

Family

ID=19853363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK615789A DK615789A (da)	1988-12-12	1989-12-07	Fremgangsmaade til fotokemisk omdannelse af tachysterolforbindelser til prae-vitamin d forbindelser og af trans-vitamin d forbindelser til cis-vitamin d forbindelser

Country Status (11)

Country	Link
US (1)	US5035783A (da)
EP (1)	EP0373687B1 (da)
JP (1)	JPH02202870A (da)
AT (1)	ATE90075T1 (da)
AU (1)	AU622958B2 (da)
CA (1)	CA2004816A1 (da)
DE (1)	DE68906866T2 (da)
DK (1)	DK615789A (da)
ES (1)	ES2055019T3 (da)
IL (1)	IL92635A0 (da)
ZA (1)	ZA899375B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE124394T1 (de) *	1990-04-27	1995-07-15	Duphar Int Res	Verfahren zur photochemischen isomerisierung von organischen verbindungen unter dem einfluss eines photosensibilisators.
US5543016A (en) *	1991-07-12	1996-08-06	Inrad	Photoconversion of steroids in microreactors
US6242434B1 (en) *	1997-08-08	2001-06-05	Bone Care International, Inc.	24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) *	1995-04-03	2002-12-05	Bone Care International, Inc.	Method for treating and preventing hyperparathyroidism
US20040043971A1 (en) *	1995-04-03	2004-03-04	Bone Care International, Inc.	Method of treating and preventing hyperparathyroidism with active vitamin D analogs
JP2002516306A (ja)	1998-05-29	2002-06-04	ボーンケアインターナショナルインコーポレイテッド	ヒドロキシ−２５−エン−ビタミンｄ化合物の製造方法
US5972917A (en) *	1998-05-29	1999-10-26	Bone Care Int Inc	1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
WO2000053578A1 (en) *	1999-03-11	2000-09-14	Kuraray Co., Ltd.	Vitamin d derivatives and process for the preparation thereof
US7351869B2 (en) *	2002-11-18	2008-04-01	Teva Pharmaceutical Industries Ltd	Crystallization method for purification of calcipotriene
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20190116791A1 (en) *	2016-03-15	2019-04-25	Fmc Corporation	Use of safeners with ppo inhibitor herbicides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4609444A (en) *	1982-11-16	1986-09-02	Solarchem Corporation	Photochemical reactions for commercial synthesis
US4517125A (en) *	1983-02-03	1985-05-14	Chugai Seiyaku Kabushiki Kaisha	Novel vitamin D3 derivatives and process for producing the same
US4551214A (en) *	1983-07-01	1985-11-05	Hoffmann-La Roche Inc.	Photochemical preparation of previtamin D
US4686023A (en) *	1985-11-26	1987-08-11	Solarchem Research, Division Of Brolor Investments, Ltd.	Sensitized photochemical preparation of vitamin D
NO872850L (no) *	1986-07-09	1988-01-11	Solarchem Res	Fotokjemisk sensitiverende materialer.
US4849076A (en) *	1987-10-13	1989-07-18	Neckers Douglas C	Continuous oxidation method

1989
- 1989-11-22 ES ES89202959T patent/ES2055019T3/es not_active Expired - Lifetime
- 1989-11-22 DE DE8989202959T patent/DE68906866T2/de not_active Expired - Fee Related
- 1989-11-22 AT AT89202959T patent/ATE90075T1/de active
- 1989-11-22 EP EP89202959A patent/EP0373687B1/en not_active Expired - Lifetime
- 1989-12-07 DK DK615789A patent/DK615789A/da not_active Application Discontinuation
- 1989-12-07 ZA ZA899375A patent/ZA899375B/xx unknown
- 1989-12-07 CA CA002004816A patent/CA2004816A1/en not_active Abandoned
- 1989-12-07 US US07/447,509 patent/US5035783A/en not_active Expired - Fee Related
- 1989-12-09 JP JP1320423A patent/JPH02202870A/ja active Pending
- 1989-12-11 IL IL92635A patent/IL92635A0/xx not_active IP Right Cessation
- 1989-12-11 AU AU46155/89A patent/AU622958B2/en not_active Ceased

Also Published As

Publication number	Publication date
DE68906866T2 (de)	1993-09-09
JPH02202870A (ja)	1990-08-10
AU622958B2 (en)	1992-04-30
ATE90075T1 (de)	1993-06-15
EP0373687A1 (en)	1990-06-20
CA2004816A1 (en)	1990-06-12
AU4615589A (en)	1990-06-14
DE68906866D1 (de)	1993-07-08
ZA899375B (en)	1990-08-29
ES2055019T3 (es)	1994-08-16
US5035783A (en)	1991-07-30
IL92635A0 (en)	1990-08-31
EP0373687B1 (en)	1993-06-02
DK615789D0 (da)	1989-12-07

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Legal Events

Date	Code	Title	Description
1994-08-22	AHB	Application shelved due to non-payment