DK615889A - Peptidderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat - Google Patents

Peptidderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat Download PDF

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Publication number
DK615889A
DK615889A DK615889A DK615889A DK615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A
Authority
DK
Denmark
Prior art keywords
derivative
pct
preparing
procedure
pharmaceutical preparation
Prior art date
Application number
DK615889A
Other languages
English (en)
Other versions
DK615889D0 (da
DK167813B1 (da
Inventor
Fred Widmer
Kailash Kumar Gauri
Stig Aasmul-Olsen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Publication of DK615889D0 publication Critical patent/DK615889D0/da
Priority to DK615889A priority Critical patent/DK167813B1/da
Priority to CA002069449A priority patent/CA2069449A1/en
Priority to EP91900187A priority patent/EP0504207B1/en
Priority to JP3500941A priority patent/JPH05504336A/ja
Priority to DE69030100T priority patent/DE69030100D1/de
Priority to FI922620A priority patent/FI922620A7/fi
Priority to AT91900187T priority patent/ATE149517T1/de
Priority to US07/859,714 priority patent/US5411942A/en
Priority to PCT/DK1990/000322 priority patent/WO1991009053A1/en
Priority to AU68989/91A priority patent/AU636427C/en
Priority to HU921883A priority patent/HUT61322A/hu
Priority to KR1019920701341A priority patent/KR927003631A/ko
Publication of DK615889A publication Critical patent/DK615889A/da
Priority to NO92922229A priority patent/NO922229L/no
Priority to LVP-92-320A priority patent/LV10107B/en
Application granted granted Critical
Publication of DK167813B1 publication Critical patent/DK167813B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK615889A 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat DK167813B1 (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
AT91900187T ATE149517T1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
PCT/DK1990/000322 WO1991009053A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
JP3500941A JPH05504336A (ja) 1989-12-07 1990-12-07 ペプチド誘導体，その製法，これを含む医薬品及び緑内障の治療法
DE69030100T DE69030100D1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
FI922620A FI922620A7 (fi) 1989-12-07 1990-12-07 Peptidijohdannainen, menetelmä sen valmistamiseksi, sitä sisältävä far maseuttinen valmiste ja menetelmä glaukooman hoitamiseksi
CA002069449A CA2069449A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
US07/859,714 US5411942A (en) 1989-12-07 1990-12-07 Peptide derivative, pharmaceutical preparation containing it and method for treatment of glaucoma
EP91900187A EP0504207B1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it
AU68989/91A AU636427C (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
HU921883A HUT61322A (en) 1989-12-07 1990-12-07 Process for producing peptide derivatives suitable for treating glaucoma and pharmaceutical compositions comprising same as active ingredient
KR1019920701341A KR927003631A (ko) 1989-12-07 1990-12-07 펩티드 유도체, 그 제조방법, 이를 함유한 제제 및 녹내장의 치료방법
NO92922229A NO922229L (no) 1989-12-07 1992-06-05 Peptid derivativ, fremgangsmaate til fremstilling av dissefarmasoeytiske preparater som inneholder disse og fremgangsmaate for behandling av glaucoma
LVP-92-320A LV10107B (en) 1989-12-07 1992-12-17 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
DK615889 1989-12-07

Publications (3)

Publication Number Publication Date
DK615889D0 DK615889D0 (da) 1989-12-07
DK615889A true DK615889A (da) 1991-06-08
DK167813B1 DK167813B1 (da) 1993-12-20

Family

ID=8147734

Family Applications (1)

Application Number Title Priority Date Filing Date
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Country Status (12)

Country Link
US (1) US5411942A (da)
EP (1) EP0504207B1 (da)
JP (1) JPH05504336A (da)
KR (1) KR927003631A (da)
AT (1) ATE149517T1 (da)
CA (1) CA2069449A1 (da)
DE (1) DE69030100D1 (da)
DK (1) DK167813B1 (da)
FI (1) FI922620A7 (da)
HU (1) HUT61322A (da)
LV (1) LV10107B (da)
WO (1) WO1991009053A1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US6083913A (en) * 1995-06-07 2000-07-04 Glaxo Wellcome Inc. Peptides and compounds that bind to a thrombopoietin receptor
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
GB9818938D0 (en) 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US8283315B2 (en) * 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
ES2781475T3 (es) 2002-09-18 2020-09-02 Janssen Pharmaceuticals Inc Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas
US20040171554A1 (en) * 2003-02-07 2004-09-02 Genentech, Inc. Compositions and methods for enhancing apoptosis
US8076060B2 (en) * 2003-08-04 2011-12-13 Emil William Chynn Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma
SG131110A1 (en) * 2003-08-28 2007-04-26 Ortho Mcneil Pharm Inc Peptides and compounds that bind to thrombopoietin receptors
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
AU2005228950B2 (en) * 2004-03-23 2012-02-02 Genentech, Inc. Azabicyclo-octane inhibitors of IAP
DK2253614T3 (da) 2004-04-07 2013-01-07 Novartis Ag IAP-inhibitorer
KR100984459B1 (ko) * 2004-07-02 2010-09-29 제넨테크, 인크. Ｉａｐ의 억제제
US20060210542A1 (en) * 2004-08-16 2006-09-21 Yurkow Edward J Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia
DK1836201T4 (da) * 2004-12-20 2013-11-11 Genentech Inc Pyrrolidininhibitorer af IAP.
CN101374829A (zh) * 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂
PE20110220A1 (es) 2006-08-02 2011-04-11 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
NZ577150A (en) * 2006-12-19 2012-04-27 Genentech Inc Imidazopyridine inhibitors of iap
JP2010524467A (ja) * 2007-04-16 2010-07-22 モメンタ ファーマシューティカルズ インコーポレイテッド 規定の糖タンパク質産物および関連の方法
WO2008134679A1 (en) * 2007-04-30 2008-11-06 Genentech, Inc. Inhibitors of iap
AU2009203971A1 (en) * 2008-01-11 2009-07-16 Genentech, Inc. Inhibitors of IAP
JP2011529962A (ja) 2008-08-02 2011-12-15 ジェネンテック， インコーポレイテッド Ｉａｐのインヒビター
US20110218211A1 (en) * 2008-08-16 2011-09-08 Genentech, Inc. Azaindole inhibitors of iap
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
WO2011127322A1 (en) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. High mannose glycans
EP2686671A4 (en) 2011-03-12 2015-06-24 Momenta Pharmaceuticals Inc N-GLYCANES CONTAINING N-ACETYLHEXOSAMINE IN GLYCOPROTEIN PRODUCTS
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
EP2877589B1 (en) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
EP4125994A4 (en) * 2020-03-25 2024-06-12 Aufbau Medical Innovations Limited METHODS AND MEDICAL TREATMENTS FOR GLAUCOMA

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457489A (en) * 1981-07-13 1984-07-03 Gilmore Samuel E Subsea fluid conduit connections for remote controlled valves
EP0088350B1 (en) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
US4634698A (en) * 1984-09-24 1987-01-06 Schering Corporation Antiglaucoma agents
US4918008A (en) * 1985-01-18 1990-04-17 Gauri Kailash Kumar Process for the preparation of protein hydrolysate and medicaments containing these hydrolysates
IL86386A0 (en) * 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
GB8728560D0 (en) * 1987-12-07 1988-01-13 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
FI922620L (fi) 1992-06-05
FI922620A0 (fi) 1992-06-05
DE69030100D1 (de) 1997-04-10
CA2069449A1 (en) 1991-06-08
ATE149517T1 (de) 1997-03-15
LV10107B (en) 1995-02-20
WO1991009053A1 (en) 1991-06-27
DK615889D0 (da) 1989-12-07
US5411942A (en) 1995-05-02
LV10107A (lv) 1994-05-10
JPH05504336A (ja) 1993-07-08
DK167813B1 (da) 1993-12-20
EP0504207A1 (en) 1992-09-23
EP0504207B1 (en) 1997-03-05
KR927003631A (ko) 1992-12-18
HUT61322A (en) 1992-12-28
HU9201883D0 (en) 1992-09-28
AU636427B2 (en) 1993-04-29
FI922620A7 (fi) 1992-06-05
AU6898991A (en) 1991-07-18

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed