DK615889A - Peptidderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat - Google Patents

Peptidderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat Download PDF

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Publication number
DK615889A
DK615889A DK615889A DK615889A DK615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A
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DK
Denmark
Prior art keywords
derivative
pct
preparing
procedure
pharmaceutical preparation
Prior art date
Application number
DK615889A
Other languages
English (en)
Other versions
DK167813B1 (da
DK615889D0 (da
Inventor
Fred Widmer
Kailash Kumar Gauri
Stig Aasmul-Olsen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Publication of DK615889D0 publication Critical patent/DK615889D0/da
Priority to DK615889A priority Critical patent/DK167813B1/da
Priority to FI922620A priority patent/FI922620A7/fi
Priority to AT91900187T priority patent/ATE149517T1/de
Priority to CA002069449A priority patent/CA2069449A1/en
Priority to HU921883A priority patent/HUT61322A/hu
Priority to EP91900187A priority patent/EP0504207B1/en
Priority to JP3500941A priority patent/JPH05504336A/ja
Priority to PCT/DK1990/000322 priority patent/WO1991009053A1/en
Priority to KR1019920701341A priority patent/KR927003631A/ko
Priority to DE69030100T priority patent/DE69030100D1/de
Priority to US07/859,714 priority patent/US5411942A/en
Priority to AU68989/91A priority patent/AU636427C/en
Publication of DK615889A publication Critical patent/DK615889A/da
Priority to NO92922229A priority patent/NO922229L/no
Priority to LVP-92-320A priority patent/LV10107B/en
Application granted granted Critical
Publication of DK167813B1 publication Critical patent/DK167813B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK615889A 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat DK167813B1 (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
JP3500941A JPH05504336A (ja) 1989-12-07 1990-12-07 ペプチド誘導体,その製法,これを含む医薬品及び緑内障の治療法
KR1019920701341A KR927003631A (ko) 1989-12-07 1990-12-07 펩티드 유도체, 그 제조방법, 이를 함유한 제제 및 녹내장의 치료방법
CA002069449A CA2069449A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
HU921883A HUT61322A (en) 1989-12-07 1990-12-07 Process for producing peptide derivatives suitable for treating glaucoma and pharmaceutical compositions comprising same as active ingredient
EP91900187A EP0504207B1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it
FI922620A FI922620A7 (fi) 1989-12-07 1990-12-07 Peptidijohdannainen, menetelmä sen valmistamiseksi, sitä sisältävä far maseuttinen valmiste ja menetelmä glaukooman hoitamiseksi
PCT/DK1990/000322 WO1991009053A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
AT91900187T ATE149517T1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
DE69030100T DE69030100D1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
US07/859,714 US5411942A (en) 1989-12-07 1990-12-07 Peptide derivative, pharmaceutical preparation containing it and method for treatment of glaucoma
AU68989/91A AU636427C (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
NO92922229A NO922229L (no) 1989-12-07 1992-06-05 Peptid derivativ, fremgangsmaate til fremstilling av dissefarmasoeytiske preparater som inneholder disse og fremgangsmaate for behandling av glaucoma
LVP-92-320A LV10107B (en) 1989-12-07 1992-12-17 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK615889 1989-12-07
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Publications (3)

Publication Number Publication Date
DK615889D0 DK615889D0 (da) 1989-12-07
DK615889A true DK615889A (da) 1991-06-08
DK167813B1 DK167813B1 (da) 1993-12-20

Family

ID=8147734

Family Applications (1)

Application Number Title Priority Date Filing Date
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Country Status (12)

Country Link
US (1) US5411942A (da)
EP (1) EP0504207B1 (da)
JP (1) JPH05504336A (da)
KR (1) KR927003631A (da)
AT (1) ATE149517T1 (da)
CA (1) CA2069449A1 (da)
DE (1) DE69030100D1 (da)
DK (1) DK167813B1 (da)
FI (1) FI922620A7 (da)
HU (1) HUT61322A (da)
LV (1) LV10107B (da)
WO (1) WO1991009053A1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
ATE390439T1 (de) 1995-06-07 2008-04-15 Glaxo Group Ltd An einem thrombopoietin rezeptor bindende peptide und zusammensetzungen
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
GB9818938D0 (en) * 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US8283315B2 (en) * 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
MXPA05003057A (es) 2002-09-18 2006-04-18 Johnson & Johnson Metodos para aumentar la produccion de celulas madre hematopoyeticas y plaquetas.
US20040171554A1 (en) * 2003-02-07 2004-09-02 Genentech, Inc. Compositions and methods for enhancing apoptosis
US8076060B2 (en) * 2003-08-04 2011-12-13 Emil William Chynn Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma
KR20120078742A (ko) * 2003-08-28 2012-07-10 오르토-맥네일 파마슈티칼, 인코퍼레이티드 수용체에 결합하는 펩티드 및 화합물
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
EP1740173A4 (en) * 2004-03-23 2009-05-27 Genentech Inc AZABICYCLOOCTAN IAP INHIBITORS
CA2560162C (en) * 2004-04-07 2013-05-21 Novartis Ag Inhibitors of iap
ES2524449T3 (es) 2004-07-02 2014-12-09 Genentech, Inc. Inhibidores de IAP
US20060210542A1 (en) * 2004-08-16 2006-09-21 Yurkow Edward J Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia
EA019420B1 (ru) * 2004-12-20 2014-03-31 Дженентех, Инк. Пирролидиновые ингибиторы иап (ингибиторов апоптоза)
US8247557B2 (en) * 2005-12-19 2012-08-21 Genentech, Inc. IAP inhibitors
PE20110218A1 (es) * 2006-08-02 2011-04-01 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
NZ577150A (en) * 2006-12-19 2012-04-27 Genentech Inc Imidazopyridine inhibitors of iap
RU2009141965A (ru) * 2007-04-16 2011-05-27 Момента Фармасьютикалз, Инк. (Us) Определенные продукты гликопротеина и способы их производства
MX2009011783A (es) * 2007-04-30 2009-12-04 Genentech Inc Inhibidores de iap.
CA2711606A1 (en) * 2008-01-11 2009-07-16 Genentech, Inc. Inhibitors of iap
CA2730448A1 (en) 2008-08-02 2010-02-11 Genentech, Inc. Inhibitors of iap
US20110218211A1 (en) * 2008-08-16 2011-09-08 Genentech, Inc. Azaindole inhibitors of iap
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
US9921210B2 (en) 2010-04-07 2018-03-20 Momenta Pharmaceuticals, Inc. High mannose glycans
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
EP2856159A4 (en) 2012-06-01 2016-04-13 Momenta Pharmaceuticals Inc METHODS RELATING TO DENOSUMAB
EP4397768A3 (en) 2012-07-26 2024-12-18 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
WO2014149067A1 (en) 2013-03-15 2014-09-25 Momenta Pharmaceuticals, Inc. Methods related to ctla4-fc fusion proteins
EP2996772B1 (en) 2013-05-13 2018-12-19 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
EP3058084A4 (en) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
CN115996742A (zh) * 2020-03-25 2023-04-21 奥夫博医疗创新有限公司 用于青光眼的方法和药剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457489A (en) * 1981-07-13 1984-07-03 Gilmore Samuel E Subsea fluid conduit connections for remote controlled valves
EP0088350B1 (en) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
US4634698A (en) * 1984-09-24 1987-01-06 Schering Corporation Antiglaucoma agents
US4918008A (en) * 1985-01-18 1990-04-17 Gauri Kailash Kumar Process for the preparation of protein hydrolysate and medicaments containing these hydrolysates
IL86386A0 (en) * 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
GB8728560D0 (en) * 1987-12-07 1988-01-13 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
LV10107B (en) 1995-02-20
AU636427B2 (en) 1993-04-29
HU9201883D0 (en) 1992-09-28
WO1991009053A1 (en) 1991-06-27
LV10107A (lv) 1994-05-10
FI922620A0 (fi) 1992-06-05
DK167813B1 (da) 1993-12-20
HUT61322A (en) 1992-12-28
DE69030100D1 (de) 1997-04-10
FI922620L (fi) 1992-06-05
JPH05504336A (ja) 1993-07-08
AU6898991A (en) 1991-07-18
CA2069449A1 (en) 1991-06-08
US5411942A (en) 1995-05-02
KR927003631A (ko) 1992-12-18
EP0504207A1 (en) 1992-09-23
EP0504207B1 (en) 1997-03-05
FI922620A7 (fi) 1992-06-05
ATE149517T1 (de) 1997-03-15
DK615889D0 (da) 1989-12-07

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed