ATE149517T1 - Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung - Google Patents

Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung

Info

Publication number
ATE149517T1
ATE149517T1 AT91900187T AT91900187T ATE149517T1 AT E149517 T1 ATE149517 T1 AT E149517T1 AT 91900187 T AT91900187 T AT 91900187T AT 91900187 T AT91900187 T AT 91900187T AT E149517 T1 ATE149517 T1 AT E149517T1
Authority
AT
Austria
Prior art keywords
pct
pharmaceutical composition
composition containing
peptide derivative
production
Prior art date
Application number
AT91900187T
Other languages
English (en)
Inventor
Fred Widmer
Kailash Kumar Gauri
Stig Aasmul-Olsen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Application granted granted Critical
Publication of ATE149517T1 publication Critical patent/ATE149517T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT91900187T 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung ATE149517T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Publications (1)

Publication Number Publication Date
ATE149517T1 true ATE149517T1 (de) 1997-03-15

Family

ID=8147734

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91900187T ATE149517T1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung

Country Status (12)

Country Link
US (1) US5411942A (de)
EP (1) EP0504207B1 (de)
JP (1) JPH05504336A (de)
KR (1) KR927003631A (de)
AT (1) ATE149517T1 (de)
CA (1) CA2069449A1 (de)
DE (1) DE69030100D1 (de)
DK (1) DK167813B1 (de)
FI (1) FI922620A7 (de)
HU (1) HUT61322A (de)
LV (1) LV10107B (de)
WO (1) WO1991009053A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US6083913A (en) * 1995-06-07 2000-07-04 Glaxo Wellcome Inc. Peptides and compounds that bind to a thrombopoietin receptor
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
GB9818938D0 (en) 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US8283315B2 (en) * 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
ES2781475T3 (es) 2002-09-18 2020-09-02 Janssen Pharmaceuticals Inc Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas
US20040171554A1 (en) * 2003-02-07 2004-09-02 Genentech, Inc. Compositions and methods for enhancing apoptosis
US8076060B2 (en) * 2003-08-04 2011-12-13 Emil William Chynn Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma
SG131110A1 (en) * 2003-08-28 2007-04-26 Ortho Mcneil Pharm Inc Peptides and compounds that bind to thrombopoietin receptors
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
AU2005228950B2 (en) * 2004-03-23 2012-02-02 Genentech, Inc. Azabicyclo-octane inhibitors of IAP
DK2253614T3 (da) 2004-04-07 2013-01-07 Novartis Ag IAP-inhibitorer
KR100984459B1 (ko) * 2004-07-02 2010-09-29 제넨테크, 인크. Iap의 억제제
US20060210542A1 (en) * 2004-08-16 2006-09-21 Yurkow Edward J Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia
DK1836201T4 (da) * 2004-12-20 2013-11-11 Genentech Inc Pyrrolidininhibitorer af IAP.
CN101374829A (zh) * 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂
PE20110220A1 (es) 2006-08-02 2011-04-11 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
NZ577150A (en) * 2006-12-19 2012-04-27 Genentech Inc Imidazopyridine inhibitors of iap
JP2010524467A (ja) * 2007-04-16 2010-07-22 モメンタ ファーマシューティカルズ インコーポレイテッド 規定の糖タンパク質産物および関連の方法
WO2008134679A1 (en) * 2007-04-30 2008-11-06 Genentech, Inc. Inhibitors of iap
AU2009203971A1 (en) * 2008-01-11 2009-07-16 Genentech, Inc. Inhibitors of IAP
JP2011529962A (ja) 2008-08-02 2011-12-15 ジェネンテック, インコーポレイテッド Iapのインヒビター
US20110218211A1 (en) * 2008-08-16 2011-09-08 Genentech, Inc. Azaindole inhibitors of iap
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
WO2011127322A1 (en) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. High mannose glycans
EP2686671A4 (de) 2011-03-12 2015-06-24 Momenta Pharmaceuticals Inc N-acetylhexosamin-haltige n-glykane in glycoproteinprodukten
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
EP2877589B1 (de) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glykoproteine mit entzündungshemmenden eigenschaften
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
EP4125994A4 (de) * 2020-03-25 2024-06-12 Aufbau Medical Innovations Limited Verfahren und mittel für glaukom

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457489A (en) * 1981-07-13 1984-07-03 Gilmore Samuel E Subsea fluid conduit connections for remote controlled valves
EP0088350B1 (de) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl-Dipeptiden, Verfahren zu deren Herstellung und deren pharmazeutische Zusammensetzungen
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
US4634698A (en) * 1984-09-24 1987-01-06 Schering Corporation Antiglaucoma agents
US4918008A (en) * 1985-01-18 1990-04-17 Gauri Kailash Kumar Process for the preparation of protein hydrolysate and medicaments containing these hydrolysates
IL86386A0 (en) * 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
GB8728560D0 (en) * 1987-12-07 1988-01-13 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
FI922620L (fi) 1992-06-05
FI922620A0 (fi) 1992-06-05
DE69030100D1 (de) 1997-04-10
DK615889A (da) 1991-06-08
CA2069449A1 (en) 1991-06-08
LV10107B (en) 1995-02-20
WO1991009053A1 (en) 1991-06-27
DK615889D0 (da) 1989-12-07
US5411942A (en) 1995-05-02
LV10107A (lv) 1994-05-10
JPH05504336A (ja) 1993-07-08
DK167813B1 (da) 1993-12-20
EP0504207A1 (de) 1992-09-23
EP0504207B1 (de) 1997-03-05
KR927003631A (ko) 1992-12-18
HUT61322A (en) 1992-12-28
HU9201883D0 (en) 1992-09-28
AU636427B2 (en) 1993-04-29
FI922620A7 (fi) 1992-06-05
AU6898991A (en) 1991-07-18

Similar Documents

Publication Publication Date Title
ATE149517T1 (de) Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
MY135057A (en) Dolastatin 15 derivatives
DE4142157B4 (de) Opioid-Peptide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung
DE69429078D1 (de) Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
PT723538E (pt) Compostos triciclicos de carbamato uteis para a ainibicao da funcao da proteina g e para o tratamento de doencas proliferativas
DE69713112D1 (de) Zusammensetzungen und methoden zur behandlung von infektionen unter verwendung von indolicidin-analogen
ES2114616T5 (es) Acidos dicarboxilicos alifaticos insaturados.
DE69416676D1 (de) Verfahren zur herstellung von phenylalanin-derivaten oder homologen, die eine guanidin- oder modifizierte guanidin-gruppe enthalten, verwendbar für die herstellung von gnrh antagonistisch wirksamen peptiden
DE69104365D1 (de) Vaterit und verfahren zu dessen herstellung.
SE9101838D0 (sv) Novel peptides and their use
DE69631542D1 (de) Neue geranylgeranylderivate, verfahren zu deren herstellung und entsprechende pharmazeutische zusammensetzungen
ATE113056T1 (de) Künstliche rezeptor-analoge.
ATE246515T1 (de) Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
DE59409413D1 (de) Verwendung von n,s-diacetylcystein-ethylester (dacee) zur herstellung eines medikaments zur behandlung viraler erkrankungen
ATE25708T1 (de) Biologisch aktive konjugate, ihre herstellung und ihre anwendung.
DE3462692D1 (en) Pharmacologically active peptides
HUT61485A (en) Process for producing drug composition suitable for treating thrombocytopenia
ATE201600T1 (de) Pharmazeutische zusammensetzung in form eines kits enthaltend prostaglandin e1
BG101983A (en) Substituted phenylamidines, medicamentous forms containing them and mehtod for their preparation
ATE40698T1 (de) Peptiden, verfahren zur deren herstellung und deren pharmazeutische zusammensetzungen.
NO922229L (no) Peptid derivativ, fremgangsmaate til fremstilling av dissefarmasoeytiske preparater som inneholder disse og fremgangsmaate for behandling av glaucoma
BR9006746A (pt) Peptideo fisiologicamente ativo e agente regulador do metabolismo de calcio
DE69215085D1 (de) Aminoacylderivate von gem-diphosphonsauren,verfahren zu deren herstellung und pharmazeutische zubereitungen,die sie enthalten
JPS643161A (en) (2-cyano-2-oxyiminoacetyl)-amino acid derivative
MX9700199A (es) Composiciones de cadena invariante utiles para tratar enfermedades autoinmunes.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties