DK617184A - Thienopyrimidinderivater - Google Patents

Thienopyrimidinderivater Download PDF

Info

Publication number: DK617184A
Authority: DK; Denmark
Prior art keywords: sup; carbon atoms; alkyl group; independently represent; group
Prior art date: 1984-01-05

Application number

DK617184A

Other languages

English (en)

Other versions

DK165744B (da

DK165744C (da

DK617184D0 (da

Inventor

Kunihiro Ninomiya

Issei Nitta

Akihiro Tobe

Mitsuo Egawa

Ryoji Kikumoto

Original Assignee

Mitsubishi Chem Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-01-05

Filing date

1984-12-20

Publication date

1985-07-06

1984-12-20 Application filed by Mitsubishi Chem Ind filed Critical Mitsubishi Chem Ind

1984-12-20 Publication of DK617184D0 publication Critical patent/DK617184D0/da

1985-07-06 Publication of DK617184A publication Critical patent/DK617184A/da

1993-01-11 Publication of DK165744B publication Critical patent/DK165744B/da

1993-06-07 Application granted granted Critical

1993-06-07 Publication of DK165744C publication Critical patent/DK165744C/da

Links

RBNBDIMXFJYDLQ-UHFFFAOYSA-N thieno[3,2-d]pyrimidine Chemical class C1=NC=C2SC=CC2=N1 RBNBDIMXFJYDLQ-UHFFFAOYSA-N 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 2
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
210000004556 brain Anatomy 0.000 abstract 1
125000002993 cycloalkylene group Chemical group 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000004064 dysfunction Effects 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
DDWBRNXDKNIQDY-UHFFFAOYSA-N thieno[2,3-d]pyrimidine Chemical class N1=CN=C2SC=CC2=C1 DDWBRNXDKNIQDY-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK617184A 1984-01-05 1984-12-20 Thienopyrimidinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater DK165744C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP47984		1984-01-05
JP59000479A JPS60146891A (ja)	1984-01-05	1984-01-05	〔２，３−ｄ〕チエノピリミジン誘導体およびその塩

Publications (4)

Publication Number	Publication Date
DK617184D0 DK617184D0 (da)	1984-12-20
DK617184A true DK617184A (da)	1985-07-06
DK165744B DK165744B (da)	1993-01-11
DK165744C DK165744C (da)	1993-06-07

Family

ID=11474905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK617184A DK165744C (da)	1984-01-05	1984-12-20	Thienopyrimidinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater

Country Status (8)

Country	Link
US (1)	US4695568A (da)
EP (1)	EP0150469B1 (da)
JP (1)	JPS60146891A (da)
AT (1)	ATE35137T1 (da)
CA (1)	CA1224782A (da)
DE (1)	DE3472106D1 (da)
DK (1)	DK165744C (da)
HU (1)	HU191161B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4734418A (en) *	1984-12-14	1988-03-29	Mitsui Petrochemical Industries, Ltd.	Quinazoline compounds and antihypertensives
US4703120A (en) *	1986-04-28	1987-10-27	Ortho Pharmaceutical Corporation	Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof
GB8912335D0 (en) *	1989-05-30	1989-07-12	Smithkline Beckman Intercredit	Compounds
DE19636769A1 (de) *	1996-09-10	1998-03-12	Basf Ag	3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
JPH10298078A (ja) *	1997-05-06	1998-11-10	Mitsubishi Chem Corp	抗不安薬
GB0112494D0 (en) *	2001-05-22	2001-07-11	Arachnova Therapeutics Ltd	New therapeutic use
GB0216027D0 (en)	2002-07-10	2002-08-21	Arachnova Therapeutics Ltd	New therapeutic use
CN1668307A (zh) *	2002-07-10	2005-09-14	阿瑞科诺沃治疗有限公司	治疗功能性肠紊乱的4－(2－氟苯基)－6－甲基－2－(1－哌嗪基)噻吩并[2,3－d]嘧啶
DE10232750A1 (de) *	2002-07-18	2004-02-05	Basf Ag	Verfahren zur Herstellung von macrocyclischen Ketonen durch Dieckmann-Kondensation in der Gasphase
AU2003259373B2 (en) *	2002-08-29	2006-03-09	Dynogen Pharmaceuticals, Inc.	New therapeutic uses of (4-(2-Fluorophenyl)-6-methyl-2-(1-piperazinyl) thieno[2,3-D]pyrimidine
KR20050111318A (ko) *	2003-01-13	2005-11-24	다이노젠 파마세우티컬스, 인코포레이티드	기능성 장 질환을 치료하는 방법
ES2285407T3 (es) *	2003-01-13	2007-11-16	Dynogen Pharmaceuticals Inc.	Metodo para el tratamiento de nauseas, vomitos, arcadas o cualquiera de sus combinaciones.
CA2519379A1 (en) *	2003-04-04	2004-10-21	Dynogen Pharmaceuticals, Inc.	Method of treating lower urinary tract disorders
WO2005002583A1 (en) *	2003-07-07	2005-01-13	Mitsubishi Pharma Corporation	Use of thieno`2,3-d ! pyrimidines for the prophylaxis or treatment of hyperactivity disorder
WO2006105117A2 (en) *	2005-03-28	2006-10-05	Dynogen Pharmaceuticals, Inc.	Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
AU2007309718A1 (en) *	2006-03-31	2008-05-02	Dynogen Pharmaceuticals, Inc.	Crystalline forms of 4-(2-fluorophenyl)-6-methyl-2-(piperazin-1-yl)thieno(2,3-d)pyrimidine
US20070254899A1 (en) *	2006-03-31	2007-11-01	Dynogen Pharmaceuticals, Inc.	Soluble salts of thieno[2,3-d]pyrimidine derivatives
ES2827233T3 (es) *	2013-01-18	2021-05-20	Guangzhou Maxinovel Pharmaceuticals Co Ltd	Compuesto heterocíclico de cinco y seis miembros, y método de preparación, composición farmacéutica y uso del mismo

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3883651A (en) *	1969-08-08	1975-05-13	Boehringer Sohn Ingelheim	Pharmaceutical compositions containing a 2-(aminoalkylamino)-4-amino-thieno{8 3,2-d{9 pyrimidine and method of use
US4054656A (en) *	1975-09-10	1977-10-18	Mead Johnson & Company	Thieno[2,3-d]pyrimidine antiallergic agents
GB1570494A (en) *	1975-11-28	1980-07-02	Ici Ltd	Thienopyrimidine derivatives and their use as pesticides
ZA782648B (en) *	1977-05-23	1979-06-27	Ici Australia Ltd	The prevention,control or eradication of infestations of ixodid ticks
US4471117A (en) *	1979-06-21	1984-09-11	Janssen Pharmaceutica N.V.	3,4-Dihydro-2H-pyrimido(2,1-b)benzothiazoles
JPS5692875A (en) *	1979-12-27	1981-07-27	Dainippon Pharmaceut Co Ltd	2-aminoquinazoline derivative
EP0082023A3 (en) *	1981-12-16	1983-07-20	Sankyo Company Limited	Thienopyrimidine derivatives, their preparation and their medical use
FR2521144A1 (fr) *	1982-02-08	1983-08-12	Sanofi Sa	Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

1984
- 1984-01-05 JP JP59000479A patent/JPS60146891A/ja active Granted
- 1984-12-20 DK DK617184A patent/DK165744C/da not_active IP Right Cessation
- 1984-12-21 AT AT84116052T patent/ATE35137T1/de not_active IP Right Cessation
- 1984-12-21 EP EP84116052A patent/EP0150469B1/en not_active Expired
- 1984-12-21 DE DE8484116052T patent/DE3472106D1/de not_active Expired
- 1984-12-24 US US06/685,768 patent/US4695568A/en not_active Expired - Lifetime
- 1984-12-28 CA CA000471183A patent/CA1224782A/en not_active Expired
1985
- 1985-01-03 HU HU8513A patent/HU191161B/hu unknown

Also Published As

Publication number	Publication date
US4695568A (en)	1987-09-22
HU191161B (en)	1987-01-28
CA1224782A (en)	1987-07-28
HUT37435A (en)	1985-12-28
DK165744B (da)	1993-01-11
JPS60146891A (ja)	1985-08-02
DK165744C (da)	1993-06-07
ATE35137T1 (de)	1988-07-15
EP0150469A1 (en)	1985-08-07
EP0150469B1 (en)	1988-06-15
JPH0367071B2 (da)	1991-10-21
DE3472106D1 (en)	1988-07-21
DK617184D0 (da)	1984-12-20

Legal Events

Date	Code	Title	Description
2001-08-06	PBP	Patent lapsed

Publication	Publication Date	Title
DK617184D0 (da)	1984-12-20	Thienopyrimidinderivater
EP0401958A3 (en)	1991-04-03	Photochromic compound, composition and use thereof
ATE37179T1 (de)	1988-09-15	Dihydropyridazinone.
SE8603099D0 (sv)	1986-07-11	Distamycin derivatives and process for their preparation
GR3004250T3 (da)	1993-03-31
ES8703870A1 (es)	1987-03-01	Procedimiento para preparar compuestos de 5-alquil-1-fenil-2-piperazinoalquilpirazolin-3-ona.
ATE50773T1 (de)	1990-03-15	Alkylresorcinolphosphite.
ES481551A1 (es)	1980-02-01	Procedimiento de preparacion de nuevos compuestos bis (ari- loxicarboxilicos).
EP0335979A4 (en)	1992-02-26	Thienopyrimidine derivatives
ES2005031A6 (es)	1989-02-16	Procedimiento para la obtencion de 1,3-dioxolanos 2,4-disustituidos.
ES2003086A6 (es)	1988-10-16	Procedimiento de obtencion de tienoquinolicinsulfonamidas
EP0347880A3 (en)	1991-05-29	Imidazo[2,1-b]benzothiazole compounds and antiulcer compositions containing the same
DE3268541D1 (en)	1986-02-27	Benzodioxane-imidazoline compounds, their preparation and use
FI861947A0 (fi)	1986-05-09	Hexensyror.
ES8802425A1 (es)	1988-06-01	Procedimiento para preparar derivados de esparteina.
HU900728D0 (en)	1990-04-28	Process for preparation of calcium antagonistics
ES8600636A1 (es)	1985-10-16	Procedimiento de preparacion de derivados de piperacina
EP0133259A3 (en)	1985-11-06	Aminoalkyl-substituted benzene derivatives, process for production thereof, and pharmaceutical composition thereof
HUT41029A (en)	1987-03-30	Process for preparing dioxolo-benzisoxazole derivatives
MY104048A (en)	1993-10-30	New allylaminoethylazoles.
ZA874970B (en)	1988-12-28	Derivatives of 2,6-piperazinedione,their preparation processes and the pharmaceutical compositions containing them
ES455436A1 (es)	1978-04-16	Procedimiento de preparacion de acidos tienotienilcarbonife-nilalcanoicos.
ES2009283A6 (es)	1989-09-16	Procedimiento para preparar nuevos aminoacilatos de glicerol-acetal.
JO1047B1 (en)	1982-07-10	Vehicles